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117681“…Functional assays in miR-130a-5p were adopted to test the degrees of oxidative stress, mitochondrial functions, inflammation and apoptosis. Hematoxylin and eosin (HE) staining was performed to validate the myocardial injury in mice. …”
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117682por Kang, Wei, Zhang, Jinglin, Huang, Tingting, Zhou, Yuhang, Wong, Chi Chun, Chan, Ronald C. K., Dong, Yujuan, Wu, Feng, Zhang, Bin, Wu, William K. K., Chan, Michael W. Y., Cheng, Alfred S. L., Yu, Jun, Wong, Nathalie, Lo, Kwok Wai, To, Ka Fai“…Its depletion also induced early and late apoptosis. NOTCH3 was confirmed to be a direct target of two tumor suppressor microRNAs (miRNAs), namely miR-491-5p and miR-875-5p. …”
Publicado 2021
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117683por Consales, Claudia, Butera, Alessio, Merla, Caterina, Pasquali, Emanuela, Lopresto, Vanni, Pinto, Rosanna, Pierdomenico, Maria, Mancuso, Mariateresa, Marino, Carmela, Benassi, Barbara“…In response to 72-h exposure to 50-Hz MF, we demonstrated that no proliferation change and apoptosis activation occur in both 2D and 3D cultures. …”
Publicado 2020
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117684por Wang, Rui-Tao, Miao, Run-Chen, Zhang, Xing, Yang, Gang-Hua, Mu, Yi-Ping, Zhang, Zi-Yun, Qu, Kai, Liu, Chang“…Soft agar, cell invasion, migration and apoptosis assays were used to analyze the malignant phenotype influenced by FoxM1 in GBC. …”
Publicado 2021
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117685por Post, H., Hundt, J. E., Zhang, G., Depping, R., Rose, C., Langan, E. A., Paus, R.“…Under these “pathological” conditions, dermal–epidermal split formation and dyskeratosis were prominent in organ-cultured human skin, and epidermal reepithelialisation was significantly impaired (p < 0.001), associated with reduced keratinocyte proliferation (p < 0.001), cytokeratin 6 expression (p < 0.001) and increased apoptosis (p < 0.001). Moreover, markers of intracutaneous angiogenesis (CD31 immunoreactivity and the number of of CD31 positive cells and CD31 positive vessel lumina) were significantly reduced. …”
Publicado 2020
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117686“…Finally, we analyzed ration of apoptosis, necrosis in gastric cancer cells by using flow cytometry after administration of DGAT1 inhibitor. …”
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117687por de Alwis, Natasha, Beard, Sally, Binder, Natalie K., Pritchard, Natasha, Kaitu’u-Lino, Tu’uhevaha J., Walker, Susan P., Stock, Owen, Groom, Katie, Petersen, Scott, Henry, Amanda, Said, Joanne M., Seeho, Sean, Kane, Stefan C., Hui, Lisa, Tong, Stephen, Hannan, Natalie J.“…Expression of growth, apoptosis and oxidative stress genes were assessed by qPCR. …”
Publicado 2021
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117688por Jiang, Guiyang, Teramoto, Yuki, Goto, Takuro, Mizushima, Taichi, Inoue, Satoshi, Ide, Hiroki, Nagata, Yujiro, Kashiwagi, Eiji, Baras, Alexander S., Netto, George J., Yang, Zhiming, Miyamoto, Hiroshi“…Without cisplatin treatment, BXDC2-knockdown resulted in significant increases/decreases in cell proliferation/apoptosis, respectively. An ERK activator was also found to reduce BXDC2 expression. …”
Publicado 2021
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117689“…Moreover, in vitro experiments demonstrated that Huanglian decoction significantly inhibited the growth, migration, and invasiveness of HCC cells and induced cell apoptosis and G2/M phase arrest. Further analysis showed that the decoction may inhibit the growth of HCC cells by downregulating the CCNB1 expression level. …”
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117690por Punt, Simone, Malu, Shruti, McKenzie, Jodi A., Manrique, Soraya Zorro, Doorduijn, Elien M., Mbofung, Rina M., Williams, Leila, Silverman, Deborah A., Ashkin, Emily L., Dominguez, Ana Lucía, Wang, Zhe, Chen, Jie Qing, Maiti, Sourindra N., Tieu, Trang N., Liu, Chengwen, Xu, Chunyu, Forget, Marie-Andrée, Haymaker, Cara, Khalili, Jahan S., Satani, Nikunj, Muller, Florian, Cooper, Laurence J. N., Overwijk, Willem W., Amaria, Rodabe N., Bernatchez, Chantale, Heffernan, Timothy P., Peng, Weiyi, Roszik, Jason, Hwu, Patrick“…The synergy between the targets and TILs to induce apoptosis, and the mechanisms of inhibiting resistance to TILs were interrogated. …”
Publicado 2020
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117691por Zeng, Wei-Nan, Yu, Qiu-Ping, Wang, Duan, Liu, Jun-Li, Yang, Qing-Jun, Zhou, Zong-Ke, Zeng, Yi-Ping“…Induction of intrinsic apoptosis assisted in surmounting drug resistance and caused tumor cell death. …”
Publicado 2021
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117692por Ducret, Valérie, Richards, Adam J., Videlier, Mathieu, Scalvenzi, Thibault, Moore, Karen A., Paszkiewicz, Konrad, Bonneaud, Camille, Pollet, Nicolas, Herrel, Anthony“…Remarkably, we revealed transcript isoforms of key genes with functions in metabolism, apoptosis, nuclear export and as a transcriptional corepressor, expressed in either burst-performant or endurant individuals. …”
Publicado 2021
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117693por Bi, Guoshu, Zhu, Donglin, Bian, Yunyi, Huang, Yiwei, Zhan, Cheng, Yang, Yong, Wang, Qun“…Besides, we demonstrated that GTF2E2 knockdown inhibited LUAD cell proliferation, migration, invasion, and promote apoptosis in vitro, as well as attenuated tumor growth in vivo. …”
Publicado 2021
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117694por Wang, Pan, Zhao, Lu, Gong, Sheng, Xiong, Shuanglong, Wang, Junwei, Zou, Dewei, Pan, Jinyu, Deng, Yangmin, Yan, Qian, Wu, Nan, Liao, Bin“…Previous studies have suggested that hypoxic responses are regulated by hypoxia-inducible factors (HIFs), which in turn promote the malignant progression of glioblastoma (GBM) by inhibiting apoptosis and increasing proliferation; these events lead to a poor prognosis of GBM patients. …”
Publicado 2021
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117695“…Cell viability, migration, and apoptosis were evaluated using the Cell Counting Kit-8 (CCK-8), Transwell, and flow cytometry, respectively. …”
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117696por Farias, Leonardo Paiva, Vitoriano-Souza, Juliana, Cardozo, Lucas Esteves, Gama, Leonardo Dos Reis, Singh, Youvika, Miyasato, Patrícia Aoki, Almeida, Giulliana Tessarin, Rodriguez, Dunia, Barbosa, Mayra Mara Ferrari, Fernandes, Rafaela Sachetto, Barbosa, Tereza Cristina, Neto, Almiro Pires da Silva, Nakano, Eliana, Ho, Paulo Lee, Verjovski-Almeida, Sergio, Nakaya, Helder Imoto, Wilson, Robert Alan, Leite, Luciana Cezar de Cerqueira“…Notable features after three vaccinations were markers of cytotoxicity (including IL-6 and NK cells) together with growth factors and their receptors (FGFR/VEGF/EGF) and the apoptosis pathway. Indeed, there is evidence for the development of anergy after three vaccinations, borne out by the limited responses detected in samples after challenge. …”
Publicado 2021
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117697“…Human PANC-1.1B4 cells were used to establish Bmax and Kd for [(3)H]cholesterol efflux to high density lipoprotein, and minimum concentrations required to protect cell viability and reduce apoptosis to 30mM glucose and 0.25 mM palmitic acid. …”
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117698por Sui, Qiaoqi, Liu, Dingxin, Jiang, Wu, Tang, Jinghua, Kong, Lingheng, Han, Kai, Liao, Leen, Li, Yuan, Ou, Qingjian, Xiao, Binyi, Liu, Guochen, Ling, Yihong, Chen, Jiewei, Liu, Zexian, Zuo, Zhixiang, Pan, Zhizhong, Zhou, Penghui, Zheng, Jian, Ding, Pei-Rong“…T-cell cytotoxicity was assessed by apoptosis assays and flow cytometry. The pathway through which DKK1 regulates CD8+ T cells was investigated using RNA sequencing, and chromatin immunoprecipitation and luciferase reporter assays were conducted to determine the downstream transcription factors of DKK1. …”
Publicado 2021
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117699por Xue, Leixi, Zhang, Yi, Xu, Jiajun, Lu, Wentian, Wang, Qing, Fu, Jinxiang, Liu, Zhichun“…PURPOSE: Current studies on the mechanism of tumor necrosis factor-like weak inducer of apoptosis (TWEAK) in lupus nephritis (LN) mainly focus on the inflammatory pathway. …”
Publicado 2021
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117700“…Spermatogonial stem cells (SSC) were identified by flow cytometry as strong Dolichos biflorus agglutinin (sDBA) and mitochondrial activity of SSC as strongly positive for MitoSense (sMitoSense+) in intact mitochondria cells, weakly positive for MitoSense (wMitoSense+) in early apoptosis, and necrosis with 7-Aminoactinomycin-D positive (7-AAD). …”
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