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117801por Ye, Jun, Li, Renjie, Yang, Yanfang, Dong, Wujun, Wang, Yujie, Wang, Hongliang, Sun, Tong, Li, Lin, Shen, Qiqi, Qin, Caiyun, Xu, Xiaoyan, Liao, Hengfeng, Jin, Yiqun, Xia, Xuejun, Liu, Yuling“…PTX emulsion was superior in inducing apoptosis and had a more pronounced inhibitory effect on 4T1-tumor spheroids compared with PTX liposome and PTX nanoparticle. …”
Publicado 2021
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117802por Ullah, Aftab, Chen, Gang, Hussain, Abid, Khan, Hanif, Abbas, Azar, Zhou, Zhanwei, Shafiq, Muhammad, Ahmad, Saleem, Ali, Usman, Usman, Muhammad, Raza, Faisal, Ahmed, Abrar, Qiu, Zijie, Zheng, Maochao, Liu, Daojun“…PEI-Cyclam/siTGFβ polyplexes decreased inflammation, collagen deposition, apoptosis, and cell proliferation, thus ameliorating liver fibrosis. …”
Publicado 2021
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117803por Doria, Margherita, Zicari, Sonia, Cotugno, Nicola, Domínguez‐Rodríguez, Sara, Ruggiero, Alessandra, Pascucci, Giuseppe R, Tagarro, Alfredo, Rojo Conejo, Pablo, Nastouli, Eleni, Gärtner, Kathleen, Cameron, Mark, Richardson, Brian, Foster, Caroline, Williams, Sion L, Rinaldi, Stefano, De Rossi, Anita, Giaquinto, Carlo, Rossi, Paolo, Pahwa, Savita, Palma, Paolo“…Finally, RNA‐Seq analysis showed in LT an up‐regulation of genes related to NK‐activating pathways and susceptibility to apoptosis compared with ET. CONCLUSIONS: We show that early initiation of ART during infancy preserves the NK compartment and is associated with lower HIV‐1 reservoir. …”
Publicado 2021
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117804por Manrique, Helard Andres“…This case report describes a case in relation with nivolumab, an antibody that blocks PD1 protein activity, promoting apoptosis Clinical Case: 67 years-old woman, with history of vulvar melanoma since 2016, complicated by pulmonary metastases. …”
Publicado 2021
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117805por Shao, Ying, Saredy, Jason, Xu, Keman, Sun, Yu, Saaoud, Fatma, Drummer, Charles, Lu, Yifan, Luo, Jin J., Lopez-Pastrana, Jahaira, Choi, Eric T., Jiang, Xiaohua, Wang, Hong, Yang, Xiaofeng“…Additionally, an increase of the regulators of mitotic catastrophe cell death, apoptosis, ferroptosis, inflammasomes-driven pyroptosis in ECs infected with MERS-CoV and the upregulation of pro-thrombogenic factors increase thromboembolism potential. …”
Publicado 2021
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117806“…Some cells bypass elimination, due to either aging, apoptosis via mutations or abnormal prolongation of the mitotic cycle, and enter the telomere crisis period, where large-scale DNA reorganization occurs repeatedly, which manifests as the precancerous cell cycle. …”
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117807por Cui, Sheng, Luo, Kang, Quan, Yi, Lim, Sun Woo, Shin, Yoo Jin, Lee, Kyung Eun, Kim, Hong Lim, Ko, Eun Jeong, Kim, Ju Hwan, Chung, Sang J., Bae, Soo Kyung, Chung, Byung Ha, Yang, Chul Woo“…CoQ(10)-W administration reduced oxidative stress and apoptosis markers. Mitochondrial ultrastructure assessment revealed that the addition of CoQ(10)-L or CoQ(10)-W with Tac increased mitochondrial size and number than Tac treatment alone. …”
Publicado 2021
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117808por Shang, Wenqian, Zhang, Jing, Song, Haibo, Zhu, Shunfei, Zhang, Aimin, Hua, Yushuang, Han, Shujun, Fu, Yan“…In addition, in vitro experiments showed that tetrandrine significantly inhibited cell proliferation and induced apoptosis in Ishikawa and HEC-1-B cells in dose- and time-dependent manners. …”
Publicado 2021
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117809por Du, Yipeng, Li, Xiaoting, Yan, Wenying, Zeng, Zhaohua, Han, Dunzheng, Ouyang, Hong, Pan, Xiudi, Luo, Bihui, Zhou, Bohua, Fu, Qiang, Lu, Dongfeng, Huang, Zheng, Li, Zhiliang“…The differentially expressed proteins were more pronounced in the pathways of apoptosis and energy metabolism. CONCLUSION: In conclusion, mutant MetRS allows efficient and specific identification of dynamic cell proteomics in situ, which reflect the functions and adaptive changes of MSCs that may be leveraged to understand and improve stem cell therapy in critical limb ischemia.…”
Publicado 2021
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117810“…Cell colony formation, cell cycle distribution, and apoptosis were gauged by colony formation assay and flow cytometry, respectively. …”
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117811por Liu, Hailin, Hu, Xiangnan, Jiang, Rong, Cai, Jianghui, Lin, Qiao, Fan, Zhiguo, Zhao, Pan, Wang, Song, Zou, Chunqiao, Du, Weimin, Dong, Zhi, Liu, Yingju“…CQMUH-011 was seen to induce apoptosis in activated microglia by regulating the expression of Bax and Bcl-2. …”
Publicado 2021
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117812por Qian, Ye, Zhang, Yan, Ji, Haoming, Shen, Yucheng, Zheng, Liangfeng, Cheng, Shouliang, Lu, Xiaomin“…Functional assays were applied to measure cell proliferation, apoptosis and migration. Besides, mechanism experiments were employed for assessing the interplay among LINC01089, miR-301b-3p and StAR related lipid transfer domain containing 13 (STARD13). …”
Publicado 2021
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117813por Miao, You-Han, Mao, Li-Ping, Cai, Xiao-Juan, Mo, Xiao-Ying, Zhu, Qi-Qi, Yang, Fei-Tong, Wang, Mei-Hua“…RESULTS: Our data revealed that ZnO-NP was able to inhibit proliferation, migration, and invasion and induce apoptosis of GC cells. Meanwhile, ZnO-NP significantly reduced the half maximal inhibitory concentration (IC(50)) of DDP for the inhibition of cell proliferation of DDP-resistant SGC7901/DDP cell lines. …”
Publicado 2021
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117814“…CD44v6-O-MWNTS/drug/DOTAP/siRNA improved the effect of siRNA on the inhibition of ovarian cancer cell viability and the induction of cell apoptosis. The expression of CXCR4 was decreased by CD44v6-O-MWNTS/drug/DOTAP/siRNA in ovarian cancer cells. …”
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117815“…Further, we observed a decrease in apoptosis of neurons in mice treated with MCC950. NLRP3 inhibition also prevented middle cerebral artery vasospasm in the delayed (5 days post-SAH) phase and blunted SAH-induced sensorimotor deficits. …”
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117816por Fu, Yu, Xin, Zhili, Ling, Ziji, Xie, Hanyu, Xiao, Tao, Shen, Xin, Lin, Jialin, Xu, Ling, Jiang, Hongbing“…METHODS: MicroRNA (miRNA) sequencing analysis was used to identify the possible miRNAs implicated in FD. The proliferation, apoptosis, and osteogenic differentiation of BMSCs, as well as the osteoclast-induced phenotype, were measured and compared after exogenous miR-181a-5p transfection into FD BMSCs or miR-181a-5p inhibitor transfection into normal BMSCs. …”
Publicado 2021
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117817por Probst, Stephanie, Fels, Johannes, Scharner, Bettina, Wolff, Natascha A., Roussa, Eleni, van Swelm, Rachel P. L., Lee, Wing-Kee, Thévenod, Frank“…Hepcidin or catalase expression were evaluated by RT-PCR, qPCR, immunoblotting or immunofluorescence microscopy, and cell fate by MTT, apoptosis and necrosis assays. Reactive oxygen species (ROS) were detected using CellROX™ Green and catalase activity by fluorometry. …”
Publicado 2021
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117818por Bondarev, Dmitriy, Sipilä, Sarianna, Finni, Taija, Kujala, Urho M., Aukee, Pauliina, Kovanen, Vuokko, Laakkonen, Eija K., Kokko, Katja“…METHODS: Data were drawn from the Estrogenic Regulation of Muscle Apoptosis (ERMA) study in which women 47 to 55 years were randomly selected from the Finnish National Registry. …”
Publicado 2021
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117819“…Furthermore, the downregulation of CBX2 was found to promote CRC cell apoptosis. CONCLUSIONS: Based on these findings, CBX2 may function as an oncogene and potential prognostic biomarker. …”
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117820“…Our results showed that Cur@α-NTP-LNs were effective and superior to free Cur on NPC cell-specific targeting, suppressing cell proliferation and inducing cell apoptosis. In vivo and ex vivo optical imaging revealed that Cur@α-NTP-LNs exerted high targeting efficiency, specifically accumulating in NPC xenograft tumors and delivering Cur into the tumor center after systemic administration. …”
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