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119501por Olajide, Joshua Seun, Qu, Zigang, Yang, Shunli, Yang, Bin, Xu, Xiao, Wang, Jing, Cai, Jianping“…In both systems, ferroptosis and necroptosis were common across the parasite’s infectious cycle while apoptosis occurred at 68 hpi. CONCLUSION: The proteomic data indicate that E. falciformis infection co-opts cellular and humoral responses through EV secretions, and that, host cell death and ionic imbalance are associated with E. falciformis infection. …”
Publicado 2023
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119502por Dharmarajan, Subramanian, Carrillo, Casandra, Qi, Zhonghua, Wilson, Jonathan M., Baucum, Anthony J., Sorenson, Christine M., Sheibani, Nader, Belecky-Adams, Teri L.“…Moreover, IFNγ plays a critical role in reducing pericyte survival in the retina by reducing activation of the PDGFRβ signalling pathway and increasing PKCδ levels and pericyte apoptosis. GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains peer-reviewed but unedited supplementary material available at 10.1007/s00125-023-05995-4.…”
Publicado 2023
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119503por Zhang, Ang, Wang, Shenyu, Sun, Yao, Zhang, Yikun, Zhao, Long, Yang, Yang, Zhang, Yijian, Xu, Lei, Lei, Yangyang, Du, Jie, Chen, Hu, Duan, Lian, He, Mingyi, Shi, Lintao, Liu, Lei, Wang, Quanjun, Hu, Liangding, Zhang, Bin“…Additionally, PE CAR showed ameliorative differentiation, exhaustion, and apoptosis phenotypes as assessed by flow cytometry, RNA-sequencing, and metabolic parameter analysis, after encountering CD19 + PDL1 + tumor cells. …”
Publicado 2023
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119504por Tong, Xiao, Dang, Xuan, Liu, Dongmei, Wang, Ning, Li, Miao, Han, Jianbin, Zhao, Jinjin, Wang, Yueqing, Huang, Meijiao, Yang, Yanliang, Yang, Yuhang, Wang, Weili, Kou, Yan, Kou, Junjie“…RESULTS: The vitro co-cultured results showed that the amount of plasma-derived exosomes have an increase in patients with coronary artery disease, and the inflammation and apoptosis of endothelial cells were exacerbated. Over-expression of circ_0001785 reduced endothelial cell injury through the ceRNA network pathway of miR-513a-5p/TGFBR3. …”
Publicado 2023
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119505“…Lentiviral knockdown of DEC1 in three breast epithelial cell lines was generated and will be used in cancer hallmark assays on proliferation, apoptosis, survival, and migration to assess the functional role of DEC1 in BCa. …”
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119506“…The binding of SARS-CoV-2 toACE2 receptors resulting in beta cell apoptosis and an ensuing cascade ofvirion, redox and cytokine storms are the simplified mechanisms of type 1 and 2diabetes development respectively, in COVID patients(2). …”
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119507por Francomano, Davide, Iuliano, Stefano, Condorelli, Rosita Angela, Cannarella, Rossella, La Vignera, Sandro, Calogero, Aldo E, Greco, Emanuela A, Antonini, Gabriele, Aversa, Antonio“…PRP plays a crucial role in nerve cell regeneration, axon myelinization, progenitor cell homing and migration, and anti-fibrosis and anti-apoptosis of damaged cavernous nerve, and vascular corporal tissues (J Endocrinol 2001;170:395). …”
Publicado 2023
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119508por Zuberi, Azna, Huang, Yongchao, Dotts, Ariel J, Wei, Helen, Coon V, John S, Lizuka, Takashi, Wu, Olivia, Sotos, Olivia, Chakravarti, Debabrata, Dai, Yang, Bulun, Serdar Ekrem, Yin, Ping“…Incubation of primary mut-MED12 LM cells with tryptophan or kynurenine stimulated AHR nuclear translocation, increased proliferation, inhibited apoptosis and induced AHR-target gene expression, whereas blocking the TDO2-kynurenine-AHR pathway by siRNA or pharmacologically abolished these effects. …”
Publicado 2023
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119509“…Mechanistically, RO induced apoptosis in EOC, and suppressed ALDH activity, indicating that the inhibitor suppresses stem cell-like activity of EOC. …”
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119510“…Notch signaling is known for its roles in development, cell fate, cell differentiation, apoptosis and proliferation. Notch is a family of intermembrane receptors. …”
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119511“…SRM had similar ENSC mitosis-driving capacity to NSM, but was superior in driving ENSC differentiation in company with heightened ENSC apoptosis. Enteric neurospheres were motile, capable of merging together. …”
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119512por Liao, Chaoliang, Li, Min, Chen, Xue, Tang, Chenpeng, Quan, Jing, Bode, Ann M., Cao, Ya, Luo, Xiangjian“…METHODS: Trypan blue staining, colony formation assay, flow cytometry, and TUNEL staining, as well as the detection of apoptosis and anoikis resistance‐related markers was applied to evaluate the anoikis-resistant capability of NPC cells cultured in ultra-low adhesion condition. …”
Publicado 2023
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119513por Sabbah, Rawan, Saadi, Sahar, Shahar-Gabay, Tal, Gerassy, Shiran, Yehudai-Resheff, Shlomit, Zuckerman, Tsila“…CONCLUSIONS: This study has disclosed direct contribution of impaired functional, genetic and molecular properties of AML patient-derived adipocytes to effective protection of AML blasts from apoptosis and to stimulation of their growth in vitro and in vivo, which overall leads to disease propagation and relapse. …”
Publicado 2023
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119514por Reis-Mendes, Ana, Ferreira, Mariana, Duarte, José Alberto, Duarte-Araújo, Margarida, Remião, Fernando, Carvalho, Félix, Sousa, Emília, Bastos, Maria Lourdes, Costa, Vera Marisa“…In conclusion, our study demonstrated that in an elderly mouse population, DOX induces cardiac inflammation, autophagy, and apoptosis in the heart in the short term. When kept for a longer period, oxidative-stress-linked pathways remained altered, as well as autophagy markers and tissue damage after DOX treatment, emphasizing the need for continuous post-treatment cardiac monitoring. …”
Publicado 2023
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119515por Lin, Yuanbang, Sheng, Mingwei, Qin, Hua, Zhang, Peng, Wang, Chunli, Fu, Wei, Meng, Xiangjun, Wang, Duowei, Hou, Yachao“…The disruption of RIPK1-IκBα interaction preserved RIPK1 degradation, triggering downstream apoptosis signal-regulating kinase 1 (ASK1) phosphorylation and inciting NIMA-related kinase 7/NOD-like receptor family pyrin domain containing 3 (NEK7/NLRP3) activation in macrophages. …”
Publicado 2023
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119516por Sundel, Margaret H., Sampaio Moura, Natalia, Cheng, Kunrong, Chatain, Oscar, Hu, Shien, Drachenberg, Cinthia B., Xie, Guofeng, Raufman, Jean-Pierre“…We did not detect a role for drug toxicity, cellular senescence, or apoptosis in mediating M(1)R agonist-induced attenuated cell proliferation. …”
Publicado 2023
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119517por Liu, Dan, Guan, Xiaohong, Liu, Wenqiang, Jia, Yanping, Zhou, Hong, Xi, Chenxiang, Zhao, Mei, Fang, Yuan, Wu, Li, Li, Kunming“…Subsequently, UBE2C was chosen as a possible biomarker of POI because knockdown of UBE2C could inhibit the proliferation and promote the apoptosis of GCs. Immune infiltration analysis indicated that monocytes and M1 macrophages may be associated with the pathogenesis of POI. …”
Publicado 2023
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119518“…A bioinformatic analysis of existing databases revealed that various cell proliferation and apoptosis pathways, including the mammalian target of rapamycin (mTOR)–phosphoinositide 3-kinase (PI3K)–AKT signaling pathways, might participate in the underlying regulatory mechanism. …”
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119519por Schielke, Jan, Ittermann, Till, Groß, Stefan, Moritz, Eileen, Nauck, Matthias, Friedrich, Nele, Schwedhelm, Edzard, Rauch, Bernhard H., Völzke, Henry, Bülow, Robin, Chamling, Bishwas, Felix, Stephan Burkhard, Bahls, Martin, Dörr, Marcus, Markus, Marcello Ricardo Paulista“…AIMS: Sphingosine-1-phosphate (S1P) is a signaling lipid, which is involved in several cellular processes including cell growth, proliferation, migration and apoptosis. The associations of serum S1P levels with cardiac geometry and function are still not clear. …”
Publicado 2023
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119520Insulin-induced gene 2 protects against hepatic ischemia–reperfusion injury via metabolic remodelingpor Wu, Yichao, Li, Changbiao, Khan, Abid Ali, Chen, Kangchen, Su, Renyi, Xu, Shengjun, Sun, Yiyang, Gao, Fengqiang, Wang, Kai, Wang, Xiaodong, Lian, Zhengxing, Wang, Shuo, Yu, Mengyuan, Hu, Xin, Yang, Fan, Zheng, Shusen, Qiu, Nasha, Liu, Zhikun, Xu, Xiao“…Liver injury was assessed by monitoring hepatic histology, inflammatory responses, and apoptosis. Hypoxia/reoxygenation stimulation (H/R) of primary hepatocytes and hypoxia model induced by cobalt chloride (CoCl(2)) were used for in vitro experiments. …”
Publicado 2023
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