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119781por Wang, Yong-Hong, Tao, Ya-Chao, Wu, Dong-Bo, Wang, Meng-Lan, Tang, Hong, Chen, En-Qiang“…RESULTS: For UC-MSCs suspended in different storage solutions, the cell apoptosis rates, ultrastructure, and survival rates of mice were similar, and no differences were observed. …”
Publicado 2021
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119782por Alexander, Mariam P., Mangalaparthi, Kiran K., Madugundu, Anil K., Moyer, Ann M., Adam, Benjamin A., Mengel, Michael, Singh, Smrita, Herrmann, Sandra M., Rule, Andrew D., Cheek, E. Heidi, Herrera Hernandez, Loren P., Graham, Rondell P., Aleksandar, Denic, Aubry, Marie-Christine, Roden, Anja C., Hagen, Catherine E., Quinton, Reade A., Bois, Melanie C., Lin, Peter T., Maleszewski, Joseph J., Cornell, Lynn D., Sethi, Sanjeev, Pavelko, Kevin D., Charlesworth, Jon, Narasimhan, Ramya, Larsen, Christopher P., Rizza, Stacey A., Nasr, Samih H., Grande, Joseph P., McKee, Trevor D., Badley, Andrew D., Pandey, Akhilesh, Taner, Timucin“…Coronavirus disease 2019 AKI and S-AKI, as compared to nonseptic AKI, had an enrichment of transcriptional pathways involved in inflammation (apoptosis, autophagy, major histocompatibility complex class I and II, and type 1 T helper cell differentiation). …”
Publicado 2021
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119783por Li, Yanhong, Shi, Guiying, Han, Yunlin, Shang, Haiquan, Li, Huiwu, Liang, Wei, Zhao, Wenjie, Bai, Lin, Qin, Chuan“…We also found a significant decrease in macrophage accumulation and apoptosis, an increase in expression of scavenger receptors CD36 and SRA1, a decrease in uptake of modified low–density protein (ox-LDL), and a decrease in levels of pro-inflammatory cytokines interleukin (IL)-6 and tumor necrosis factor (TNF)-α following UCSCs treatment. …”
Publicado 2021
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119784por Yang, Bingsheng, Li, Lutao, Tong, Ge, Zeng, Zhirui, Tan, Jianye, Su, Zexin, Liu, Zhengwei, Lin, Jiezhao, Gao, Wenwen, Chen, Jianping, Zeng, Sisi, Wu, Guofeng, Li, Lin, Zhu, Shuang, Liu, Qiuzhen, Lin, Lijun“…Circ_001422 knockdown markedly repressed the proliferation and metastasis and promoted the apoptosis of OS cells in vivo and in vitro, whereas circ_001422 overexpression exerted the opposite effects. …”
Publicado 2021
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119785por He, Chuan, Lu, Shan, Wang, Xuan-zhong, Wang, Chong-cheng, Wang, Lei, Liang, Shi-peng, Luo, Tian-fei, Wang, Zhen-chuan, Piao, Mei-hua, Chi, Guang-fan, Ge, Peng-fei“…In U87 and U251 cells, TMZ (200 μM) induced DNA double strand breaks (DSBs) and nuclear translocation of apoptosis inducing factor (AIF), which was accompanied by BNIP3-mediated mitophagy and FOXO3a accumulation in nucleus. …”
Publicado 2021
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119786“…In contrast, for young HSC which were found with different cell cycle phase progression, its specific module highlighted upregulation of HIF1A hypoxic factor, PDE4B immune marker, DRAK2 (STK17B) T cell apoptosis regulator, and MYADM myeloid-associated marker. …”
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119787por Zhu, Linwen, Li, Zhe, Yu, Xiuchong, Ruan, Yao, Shen, Yijing, Shao, Yongfu, Zhang, Xinjun, Ye, Guoliang, Guo, Junming“…After transfecting cell lines with a tRF-5026a mimic or inhibitor, cell proliferation, colony formation, migration, apoptosis, and cell cycle were evaluated. The expression levels of related proteins in the PTEN/PI3K/AKT pathway were also analyzed by Western blotting. …”
Publicado 2021
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119788por Wu, Xiang, Li, Jin, Yan, Tingyuan, Ke, Xueping, Li, Xin, Zhu, Yumin, Yang, Jianrong, Li, Zhongwu“…Moreover, HOXB7 knockdown significantly inhibited cell proliferation, migration and invasion and induced cell apoptosis in HNSCC cells, and resulted in compromised tumour growth in vivo. …”
Publicado 2021
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119789por Goonetilleke, Mihiri, Kuk, Nathan, Correia, Jeanne, Hodge, Alex, Moore, Gregory, Gantier, Michael P., Yeoh, George, Sievert, William, Lim, Rebecca“…Emerging therapies in NASH target known pathological processes involved in the progression of the disease including inflammation, fibrosis, oxidative stress and hepatocyte apoptosis. Human amniotic epithelial cells (hAECs) were previously shown to be beneficial in experimental models of chronic liver injury, reducing hepatic inflammation and fibrosis. …”
Publicado 2021
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119790por Nabiyeva, Tomiris, Roufosse, Basile, Odachowski, Matylda, Baumgartner, Judith, Marschner, Christoph, Verma, Akalesh Kumar, Blom, Burgert“…Finally, complexes 3 and 7–11 were investigated for potential anticancer activities considering cell cytotoxicity and apoptosis assays against Dalton’s lymphoma (DL) and Ehrlich ascites carcinoma (EAC) malignant cancer cell lines. …”
Publicado 2021
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119791por Seeling, Carolin, Lechel, André, Svinarenko, Michael, Möller, Peter, Barth, Thomas F. E., Mellert, Kevin“…Treating chordoma cell lines with the complex formation inhibiting peptide HXR9 induced cFOS mediated apoptosis in all chordoma cell lines tested. This effect was significantly stronger in cell lines established from chordoma relapses. …”
Publicado 2021
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119792por Liang, Hui, Wu, Jian-Guo, Wang, Fei, Chen, Bo-Xuan, Zou, Shi-Tian, Wang, Cong, Luo, Shuai-Wu“…Some studies have reported that caspase-3, which is induced by various factors, is involved in the apoptosis of tumor cells. AIM: To investigate the expression of caspase-3 and HIF-1α and their relationship to the prognosis of patients with primary HCC complicated by pathological changes of hemorrhage and necrosis. …”
Publicado 2021
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119793por Moon, Seo Yun, Lee, Heejin, Kim, Seoree, Hong, Ji Hyung, Chun, Sang Hoon, Lee, Hee Yeon, Kang, Keunsoo, Kim, Ho Shik, Won, Hye Sung, Ko, Yoon Ho“…Both dasatinib (Src inhibitor) and stattic (STAT3 inhibitor) inhibited cell proliferation and induced apoptosis in TamR cells. However, stattic showed a much stronger effect than dasatinib. …”
Publicado 2021
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119794“…RESULTS: YZR-0.4 g and YZR-0.8 g treatments markedly reduced cerebral infarction, attenuated neurological deficits, and significantly downregulated the expression of phospho-apoptosis signal-regulating kinase 1 (p-ASK1)/ASK1, tumor necrosis factor receptor-associated factor 3 (TRAF3), TRAF3-interacting JNK-activating modulator (T3JAM), ionized calcium-binding adapter molecule 1 (Iba1), p-JNK/JNK, inducible nitric oxide synthase, cyclooxygenase-2, tumor necrosis factor-α, toll-like receptor 4 (TLR4), glial fibrillary acidic protein (GFAP), nuclear factor-kappa B (NF-κB), and interleukin-6 in the penumbral cortex at 1 day after reperfusion. …”
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119795“…The results showed that dietary ADP supplementation tended to increase the villus height (p = 0.077) and villus width (p = 0.062), and decrease the apoptosis rate (p = 0.081) in the duodenum of broilers under HS. …”
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119796por Xiong, Kangping, Wang, Gang, Peng, Tianchen, Zhou, Fenfang, Chen, Siming, Liu, Wei, Ju, Lingao, Xiao, Yu, Qian, Kaiyu, Wang, Xinghuan“…Cell cycle distribution and apoptosis were detected by flow cytometry. Immunofluorescence staining and western blot analysis were used to detect the expression of cell cycle-related proteins and epithelial-mesenchymal transition (EMT)-related proteins. …”
Publicado 2021
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119797por Peng, Gong, Wang, Yin, Ge, Pengfei, Bailey, Christopher, Zhang, Peng, Zhang, Di, Meng, Zhaoli, Qi, Chong, Chen, Qian, Chen, Jingtao, Niu, Junqi, Zheng, Pan, Liu, Yang, Liu, Yan“…HIF1α inhibitor Echinomycin induces GBM cell apoptosis and effectively inhibits growth of GBM in vivo by simultaneously targeting HIF1α-PDGFD/PDGFRα-AKT feedforward pathway. …”
Publicado 2021
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119798por Wong, Yuk Lung, Lautenschläger, Ingmar, Hummitzsch, Lars, Zitta, Karina, Cossais, François, Wedel, Thilo, Rusch, Rene, Berndt, Rouven, Gruenewald, Matthias, Weiler, Norbert, Steinfath, Markus, Albrecht, Martin“…RESULTS: I/R-injury decreased intestinal galactose uptake (iIPC group: p<0.001), increased vascular perfusion pressure (iIPC group: p<0.001; eIPC group: p<0.01) and attenuated venous flow (iIPC group: p<0.05) while lactate-to-pyruvate ratio (iIPC group, eIPC group: p<0.001), luminal flow (iIPC group: p<0.001; eIPC group: p<0.05), goblet cell ratio (iIPC group, eIPC group: p<0.001) and apoptosis (iIPC group, eIPC group: p<0.05) were all increased. …”
Publicado 2021
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119799por Li, Lilan, Li, Yu, He, Bingqiang, Li, Hui, Ji, Huiyuan, Wang, Yingjie, Zhu, Zhenjie, Hu, Yuming, Zhou, Yue, Yang, Ting, Sun, Chunshuai, Yuan, Ying, Wang, Yongjun“…Heat shock transcription factor 1 (HSF1) plays roles in protecting cells from stress-induced apoptosis and in controlling inflammatory activation. …”
Publicado 2021
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119800por Chang, Zhiwei, Fu, Yang, Jia, Yongxu, Gao, Ming, Song, Lijie, Zhang, Weijie, Zhao, Ruihua, Qin, Yanru“…Cell proliferation was evaluated by 3-(4, 5-dimethylthiazol-2-y1)-2, 5-diphenyl tetrazolium bromide (MTT) assay, colony formation assay and EdU assay. Cell apoptosis and invasion were detected by flow cytometry and transwell assay. …”
Publicado 2021
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