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1за авторством Maeso-Alonso, Laura, López-Ferreras, Lorena, Marques, Margarita M., Marin, Maria C.“...In this work, we will review the current understanding of p73 role as a neurogenic niche architect through the regulation of cell adhesion, cytoskeleton dynamics and Planar Cell Polarity, and give a general overview of TAp73 as a hub modulator of these functions, whose alteration could impinge in many of the Trp73(–/–) phenotypes....”
Опубліковано 2021
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2за авторством Maeso-Alonso, Laura, Alonso-Olivares, Hugo, Martínez-García, Nicole, López-Ferreras, Lorena, Villoch-Fernández, Javier, Puente-Santamaría, Laura, Colas-Algora, Natalia, Fernández-Corona, Alfonso, Lorenzo-Marcos, María Elena, Jiménez, Benilde, Holmgren, Lars, Wilhelm, Margareta, Millan, Jaime, del Peso, Luis, Claesson-Welsh, Lena, Marques, Margarita M., Marin, Maria C.“...Here, we uncover TAp73 transcription factor as a vascular architect that orchestrates transcriptional programs involved in cell junction establishment and developmental blood vessel morphogenesis and identify Angiomotin (AMOT) as a TAp73 direct transcriptional target. ...”
Опубліковано 2022
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3за авторством Marques, Margarita M., Villoch-Fernandez, Javier, Maeso-Alonso, Laura, Fuertes-Alvarez, Sandra, Marin, Maria C.“...Thus, loss of ciliary biogenesis and epithelial organization might be a common underlying cause of the diverse p73KO-phenotypes, highlighting Trp73 role as an architect of the epithelial tissue. In this review we would like to discuss the data regarding p73 role as regulator of ependymal cell ciliogenesis and PCP, supporting the view of the Trp73-mutant mice as a model that uncouples ciliogenesis from PCP and a possible model of human congenital hydrocephalus....”
Опубліковано 2019
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4за авторством Fuertes-Alvarez, Sandra, Maeso-Alonso, Laura, Villoch-Fernandez, Javier, Wildung, Merit, Martin-Lopez, Marta, Marshall, Clayton, Villena-Cortes, Alberto J., Diez-Prieto, Inmaculada, Pietenpol, Jennifer A., Tissir, Fadel, Lizé, Muriel, Marques, Margarita M., Marin, Maria C.“...These results shed light into the mechanism of ependymal cell planar polarization and reveal p73 as an epithelial architect during development regulating the cellular cytoskeleton....”
Опубліковано 2018
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