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2401
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2402“…We further show how the evolution of novel hierarchies is constrained by the architecture of central metabolism, which determines both the propensity to change ranks between pairs of substrates and the effect of specific reactions on hierarchy evolution. …”
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2403
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2404“…In this paper, we propose efficient hardware architectures for CKKS-based ENC-DEC accelerators to facilitate computations on the client side. …”
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2405por Jiang, Zhiwen, Sullivan, Patrick F., Li, Tengfei, Zhao, Bingxin, Wang, Xifeng, Luo, Tianyou, Huang, Shuai, Guan, Peter Y., Chen, Jie, Yang, Yue, Stein, Jason L., Li, Yun, Liu, Dajiang, Sun, Lei, Zhu, Hongtu“…The volume of the right ventral diencephalon shared genetic architecture with schizophrenia and educational attainment in a locus indexed by rs2361468 (located ~3kb upstream of PJA1, a conserved and ubiquitously expressed gene implicated in multiple psychiatric disorders). …”
Publicado 2023
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2406por Sudan, Jebi, Urwat, Uneeb, Farooq, Asmat, Pakhtoon, Mohammad Maqbool, Zaffar, Aaqif, Naik, Zafir Ahmad, Batool, Aneesa, Bashir, Saika, Mansoor, Madeeha, Sofi, Parvaze A., Sofi, Najeebul Ul Rehman, Shikari, Asif B., Khan, Mohd. Kamran, Hossain, Mohammad Anwar, Henry, Robert J., Zargar, Sajad Majeed“…With the advances in genome sequencing, molecular breeding, gene expression analysis and multi-omics approaches, various attempts have been made to explore the genetic architecture of rice grain pigmentation. In this review, we have compiled the current state of knowledge of the genetic architecture and nutritional value of pigmentation in rice based upon the available experimental evidence. …”
Publicado 2023
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2407“…This review discusses the structural features and regulatory roles of satellite RNAs in intracellular architecture and gene regulation.…”
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2408“…Biomolecular condensates are implicated in core cellular processes such as gene regulation and ribosome biogenesis. Although the architecture of biomolecular condensates is thought to rely on collective interactions between many components, it is unclear how the collective interactions required for their formation emerge during evolution. …”
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2409
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2410por Rasheed, Assad, Shirazi, Syed Hamad, Umar, Arif Iqbal, Shahzad, Muhammad, Yousaf, Waqas, Khan, Zakir“…Cross-scale features integration based on a bi-directional feature pyramid network (BiFPN) and wide context unit are used in the encoder of classic UNet architecture to learn spatial and local features. The decoder of the improved network has two inter-connected decoders that mutually optimize and integrate these features to produce segmentation masks. …”
Publicado 2023
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2411por Lee, Kristen, Kuang, Alan, Bain, James, Hayes, M Geoffrey, Muehlbauer, Michael, Ilkayeva, Olga, Newgard, Christopher B, Powe, Camille E, Hivert, Marie-France, Scholtens, Denise, Latimer Lowe, William“…The present findings demonstrated differences in the maternal metabolome and underlying genetic architecture of GDM with an insulin secretion defect compared to GDM with an insulin sensitivity defect. …”
Publicado 2023
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2412por Liu, Yawen, Li, Yushu, Wang, Qiyue, Ren, Jing, Ye, Chao, Li, Fangyuan, Ling, Shengjie, Liu, Yilun, Ling, DaishunEnlace del recurso
Publicado 2023
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2413por Post, Andrew R, Ho, Nancy, Rasmussen, Erik, Post, Ivan, Cho, Aika, Hofer, John, Maness, Arthur T, Parnell, Timothy, Nix, David A“…OBJECTIVES: Using agile software development practices, develop and evaluate an architecture and implementation for reliable and user-friendly self-service management of bioinformatic data stored in the cloud. …”
Publicado 2023
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2414por Sha, Zhiqiang, Warrier, Varun, Bethlehem, Richard A.I., Schultz, Laura M., Merikangas, Alison, Sun, Kevin Y., Gur, Ruben C., Gur, Raquel E., Shinohara, Russell T., Seidlitz, Jakob, Almasy, Laura, Andreassen, Ole A., Alexander-Bloch, Aaron F.“…Cumulatively, these findings provide a significant advance in our understanding of the overlapping polygenic architecture between psychopathology and cortical brain structure.…”
Publicado 2023
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2416por Turetski, Daniella, Rondina, Renante, Hutchings, Jordan, Feng, Bing, Soman, Dilip“…ABSTRACT: Despite their increasing use, choice architecture interventions have faced criticism for being possibly manipulative and unethical. …”
Publicado 2023
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2417por Stevenson, Tyler J.Enlace del recurso
Publicado 2023
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2418“…Furthermore, we identified non-coding RNAs (ncRNAs) known to regulate chromatin structures, such as MALAT1 and NEAT1, as well as several novel RNAs, RNY5, RPPH1, POLG-DT and THBS1-IT, that might modulate chromatin architecture through trans-interactions in HFFc6. Our modeling also suggests that transcripts from Alus and other repetitive elements may facilitate chromatin interactions through trans R-loop formation. …”
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2419por Alagöz, Gökberk, Eising, Else, Mekki, Yasmina, Bignardi, Giacomo, Fontanillas, Pierre, Nivard, Michel G., Luciano, Michelle, Cox, Nancy J., Fisher, Simon E., Gordon, Reyna L.“…Our results reveal an intricate shared genetic and neurobiological architecture, and lay groundwork for resolving longstanding debates about the potential co-evolution of human language and musical traits.…”
Publicado 2023
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2420“…The key to success does not rely simply on the individual components' performance, but on their optimized integration in terms of type, number, geometry, spacing, and linkers dictating the photosynthetic architecture. Natural photosynthesis has evolved along this concept, by integrating each functional component in one specialized “body” (from the Greek word “soma”) to enable the conversion of light quanta with high efficiency. …”
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