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  1. 57001
    “…Furthermore, we analyze the diversity and complexity of protein domain architectures of HECTs along the different extant eukaryotic lineages. …”
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    A Genomic Survey of HECT Ubiquitin Ligases in Eukaryotes Reveals Independent Expansions of the HECT System in Several Lineages
  2. 57002
    “…Confocal laser scanning microscopy revealed entirely different ECM architectures depending on the substrates used for biofilm induction. …”
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    Extrinsic extracellular DNA leads to biofilm formation and colocalizes with matrix polysaccharides in the human pathogenic fungus Aspergillus fumigatus
  3. 57003
    por Choi, C J, Berges, J A
    Publicado 2013
    “…We identified a novel group of metacaspases in sequenced phytoplanktonic protists that show domain architectures distinct from either type I or II enzymes; we designate them as type III. …”
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    New types of metacaspases in phytoplankton reveal diverse origins of cell death proteases
  4. 57004
    “…The objective of this work is the development of a low cost parallel solution based on GPU architectures for exhaustive search with a viable cost-benefit. …”
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    Gene regulatory networks inference using a multi-GPU exhaustive search algorithm
  5. 57005
    “…Renal and hepatic tissue from the treated groups demonstrated dose-dependent injuries, which showed architectural damage beginning in the nuclei and spreading outwards. …”
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    The effects of Euphorbia hirta on the ultrastructure of the murine liver, kidney and aorta
  6. 57006
    por Brouwer, Harm, Hoeks, John C. J.
    Publicado 2013
    “…Models of language processing that have been proposed thus far do not agree on these interpretations, and present a variety of complicated functional architectures. We put forward a very basic functional-anatomical mapping based on the recently developed Retrieval-Integration account of language comprehension (Brouwer et al., 2012). …”
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    A time and place for language comprehension: mapping the N400 and the P600 to a minimal cortical network
  7. 57007
    “…Quantitative trait loci (QTL) analysis of the progeny of a chloroquine sensitive (CQS; strain HB3)×chloroquine resistant (CQR; strain Dd2) genetic cross identifies distinct genetic architectures for CQR(CS) vs CQR(CC) phenotypes, including identification of novel interacting chromosomal loci that influence CQ LD(50). …”
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    A Process Similar to Autophagy Is Associated with Cytocidal Chloroquine Resistance in Plasmodium falciparum
  8. 57008
    “…Moreover, the screening assay described here should be readily adaptable to other organisms to study the biogenesis of different envelope architectures.…”
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    A Genome-Wide Screen for Bacterial Envelope Biogenesis Mutants Identifies a Novel Factor Involved in Cell Wall Precursor Metabolism
  9. 57009
    “…Ultrasound detected two bilateral nodules corresponding to oval opacities with well-defined edges and without calcifications or architectural distortion on mammography. Fine needle aspiration cytology performed on both breast nodules confirmed that the breast lesions were metastases from primary cutaneous malignant melanoma. …”
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    Metastatic breast disease from cutaneous malignant melanoma()
  10. 57010
    “…Typical ultrasound (US) features of hematogenous metastases include single or multiple, round to oval shaped, well-circumscribed hypoechoic masses without spiculations, calcifications, or architectural distortion; these masses are commonly located superficially in subcutaneous tissue or immediately adjacent to the breast parenchyma that is relatively rich in blood supply. …”
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    Breast Metastases from Extramammary Malignancies: Typical and Atypical Ultrasound Features
  11. 57011
    “…In pleomorphic adenomas of the salivary glands (PASG) recurrent chromosomal rearrangements affecting either 8q12 or 12q14∼15 lead to an overexpression of the genes of the genuine transcription factor PLAG1 or the architectural transcription factor HMGA2, respectively. …”
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    Correlated Expression of HMGA2 and PLAG1 in Thyroid Tumors, Uterine Leiomyomas and Experimental Models
  12. 57012
    “…Taken together, our data indicate that, at least in experimental models of brain malformations, severe seizure activity, i.e., SE plus recurrent seizures, may lead to a widespread, steadily progressive architectural, neuronal and synaptic reorganization in the brain. …”
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    Progressive Brain Damage, Synaptic Reorganization and NMDA Activation in a Model of Epileptogenic Cortical Dysplasia
  13. 57013
    “…After introducing the laboratory and the whole architectural concept the individual parts of the infrastructure are described. …”
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    Software and hardware infrastructure for research in electrophysiology
  14. 57014
    “…The paper introduces novel architectures for implementation of fully static master-slave flip-flops for low power, high performance, and high density. …”
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    A Modified Implementation of Tristate Inverter Based Static Master-Slave Flip-Flop with Improved Power-Delay-Area Product
  15. 57015
    “…These histological features are reflected in imaging findings and constitute the reasons for typical subtle mammographic features of ILC, as architectural distortion or focal asymmetries. Ultrasonography (US) may detect almost 75 % of the ILCs missed by mammography and represents the modality of choice for guiding biopsies. …”
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    Evolving concepts in breast lobular neoplasia and invasive lobular carcinoma, and their impact on imaging methods
  16. 57016
    por Burroughs, A Maxwell, Aravind, L
    Publicado 2014
    “…The predicted RNA-binding domain associated with this family is also observed in distinct architectural contexts in other proteins across phylogenetically diverse prokaryotes. …”
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    A highly conserved family of domains related to the DNA-glycosylase fold helps predict multiple novel pathways for RNA modifications
  17. 57017
    “…Previous studies from our laboratory identified the architectural transcription factor and oncogene, HMGA2, as a target of inhibition by RKIP. …”
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    RKIP and HMGA2 regulate breast tumor survival and metastasis through Lysyl Oxidase and Syndecan-2
  18. 57018
    “…Plants have acquired the capacity to grow continuously and adjust their morphology in response to endogenous and external signals, leading to a high architectural plasticity. The dynamic and differential distribution of phytohormones is an essential factor in these developmental changes. …”
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    Unraveling plant hormone signaling through the use of small molecules
  19. 57019
    “…While being phylogenetically and genomically very closely related to the facultative endosymbiont S. symbiotica from the aphid A. pisum, it shows a variety of metabolic, genetic, and architectural features, which point toward this endosymbiont being one step closer to an obligate intracellular one. …”
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    Settling Down: The Genome of Serratia symbiotica from the Aphid Cinara tujafilina Zooms in on the Process of Accommodation to a Cooperative Intracellular Life
  20. 57020
    por Adler, Miri, Mayo, Avi, Alon, Uri
    Publicado 2014
    “…This finding applies to major circuit architectures found in biological systems, including the incoherent feed-forward loop and nonlinear integral feedback loops. …”
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    Logarithmic and Power Law Input-Output Relations in Sensory Systems with Fold-Change Detection
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