“…When tested in current immunoassays, serum free T(4) values from R222I heterozygotes were more measurably abnormal in one-step vs two-step assay architectures. Total rT(3) measurements were also abnormally elevated. …”
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“…We catalogued subtle genomic alterations at the nucleotide level in the genome core and architectural rearrangements from whole-genome map comparisons. …”
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“…Common findings also include mild bronchiolar and peribronchiolar alveolar fibrosis that expands contiguous alveolar septa and leads to architectural distortion as well as centrilobular emphysema. …”
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“…Thus, the crested ibis MHC structure is entirely different from the known avian MHC architectures but similar to that of mammalian MHCs, suggesting that the fundamental structure of ancestral avian class II MHCs should be “COL11A2-IIαβ1-IIαβ2.” …”
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“…P63 positively expressed nuclei were identified, the percentage of P63 expressed nuclei was computed, and 118 textural, morphological, shape, and architectural features were calculated from each one of the 55 laryngeal lesions. …”
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“…The Arabidopsis genome encodes four homologs of ACR4 that contain sequence similarity and analogous architectural elements to ACR4, termed Arabidopsis CRINKLY4 Related (AtCRRs) proteins. …”
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“…The porous architectural characteristics of biomaterials play an important role in scaffold revascularization. …”
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“…RESULTS: Here I present TagDust2, a generic approach utilizing a library of hidden Markov models (HMM) to accurately extract reads from a wide array of possible read architectures. TagDust2 extracts more reads of higher quality compared to other approaches. …”
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“…In order to better comprehend the functional properties and the mechanism of action in TRP channels, high-resolution three-dimensional structures are indispensable, because they will yield the necessary insights into architectural intimacies at the atomic level. However, structural studies of membrane proteins are currently hampered by difficulties in protein purification and in establishing suitable crystallization conditions. …”
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“…Herein we describe a new, advanced strategy for the diversity-oriented synthesis (DOS) of macrocyclic peptidomimetics that enables the combinatorial variation of molecular scaffolds (core macrocyclic ring architectures). The generality and robustness of this DOS strategy is demonstrated by the step-efficient synthesis of a structurally diverse library of over 200 macrocyclic peptidomimetic compounds, each based around a distinct molecular scaffold and isolated in milligram quantities, from readily available building-blocks. …”
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“…Increasingly large deep learning architectures, such as Deep Belief Networks (DBNs) are the focus of current machine learning research and achieve state-of-the-art results in different domains. …”
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“…The contrast in the FF-OCT images is generated by intrinsic tissue scattering properties, meaning that no tissue staining or preparation is required. Major architectural features and tissue structures of benign breast tissue, including adipocytes, fibrous stroma, lobules and ducts were characterized. …”
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“…Unfortunately, analysis of bulk DNA masks subclonal phylogenetic architectures created by the acquisition and distribution of somatic mutations amongst cells. …”
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“…Furthermore, our study highlights the potential of the latest breakthrough PacBio chemistry to resolve complex genome architectures.…”
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“…Understanding relationships between architectural properties of gene-regulatory networks (GRNs) has been one of the major goals in systems biology and bioinformatics, as it can provide insights into, e.g., disease dynamics and drug development. …”
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“…Our results revealed that the protein architectures, intron patterns, and sequence characteristics were remarkably conserved in each subfamily. …”
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“…It is deeply expected that this work is capable of opening up a new insights into the architectural design of 1D magnetic materials and their further utilization.…”
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“…To address many challenges in RNA structure/function prediction, the characterization of RNA's modular architectural units is required. Using the RNA-As-Graphs (RAG) database, we have previously explored the existence of secondary structure (2D) submotifs within larger RNA structures. …”
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“…Modeling human aesthetic perception of visual textures is important and valuable in numerous industrial domains, such as product design, architectural design, and decoration. Based on results from a semantic differential rating experiment, we modeled the relationship between low-level basic texture features and aesthetic properties involved in human aesthetic texture perception. …”
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“…This technical note considers a simple but important methodological issue in estimating effective connectivity; namely, how do we integrate measurements from multiple subjects to infer functional brain architectures that are conserved over subjects. We offer a solution to this problem that rests on a generalization of random effects analyses to Bayesian inference about nonlinear models of electrophysiological time-series data. …”
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