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58781“…Situated 320 km to the west of Algiers, Mostaganem city encompasses a valuable cultural and architectural built heritage. The city has suffered several moderate earthquakes in recent years; this has led to extensive structural damage to old structures, especially unreinforced historical buildings. …”
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58782por Kojima, Shigehiro, Sakamoto, Tsuguo, Nagai, Yuko, Honda, Masayuki, Ogawa, Fumihiro“…The rectal and ovarian tumors were similar to transverse colon cancer in architectural and cytological atypia. Both adenocarcinomas of the transverse colon and rectum were negative for p53 in immunohistochemical staining and RAS wild type in genetic assessment. …”
Publicado 2018
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58783“…Retinal ganglion cells (RGCs) have a wide variety of dendritic architectures, which are critical for the formation of their function-specific synaptic circuitry. …”
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58784por Kelty-Stephen, Damian G.“…Tensegrity structures are prestressed architectures embodying nonlinear interactions across scales of space and time that provide context-sensitive responses faster than neural tissue can support. …”
Publicado 2018
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58785“…Future research is expected to focus on the standardization of deep learning architectures and on the optimization of the network parameters to increase performance and robustness. …”
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58786por Aper, Stijn J. A., den Hamer, Anniek, Wouters, Simone F. A., Lemmens, Lenne J. M., Ottmann, Christian, Brunsveld, Luc, Merkx, Maarten“…Using 14-3-3 proteins as a structurally well-characterized and important class of scaffold proteins, three different architectures were explored to achieve optimal protease-mediated control of scaffold activity, fusing either one or two monovalent inhibitory ExoS peptides or a single bivalent ExoS peptide to T14-3-3 using protease-cleavable linkers. …”
Publicado 2018
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58787por Adu, Kayode T., Wilson, Richard, Nichols, David S., Baker, Anthony L., Bowman, John P., Britz, Margaret L.“…We identified a novel SecB homolog as a protein export chaperone putatively involved in posttranslational translocation systems, which was down-regulated as growth temperature increased and where the modelled 3D-structure shared architectural similarities with the Escherichia coli SecB protein. …”
Publicado 2018
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58788“…However, an increase in the density of thecomplexes on the whole scaffold risks an over-eutrophic surface that harms axonal regeneration.Although theoretical predictions are yet to be validated directly by experiments, this theoretical tool can advance the treatment of SCI, and is also applicable to scaffolds with other architectures.…”
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58789“…And secondly, by deploying efficient numerical schemes to compute geodesics, our approach is not only capable of modelling macroscopic pattern formation on realistic cortical geometries, but can also be extended to include cortical architectures of more physiological relevance. Importantly, such an approach provides a means by which to investigate the influence of cortical geometry upon the nucleation and propagation of spatially localised neural activity and beyond. …”
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58790“…Furthermore, built urban environments vary in their restorative potential, but promising results have been uncovered as well. Architectural elements, cultural, and leisure areas had a restorative value, whereas the findings on streets and residential areas differ. …”
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58791por Spinelli, Giovanni, Lamberti, Patrizia, Tucci, Vincenzo, Kotsilkova, Rumiana, Tabakova, Sonia, Ivanova, Radost, Angelova, Polya, Angelov, Verislav, Ivanov, Evgeni, Di Maio, Rosa, Silvestre, Clara, Meisak, Darya, Paddubskaya, Alesia, Kuzhir, Polina“…Therefore, a careful choice of methods and materials must be made to address the final application for which these materials and further 3D printed architectures are designed.…”
Publicado 2018
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58792“…Instead, SNN models tend to be developed and simulated on computers or clusters of computers with standard von Neumann CPU architectures. Over the last decade, as well as becoming a common fixture in many workstations, NVIDIA GPU accelerators have entered the High Performance Computing field and are now used in 50 % of the Top 10 super computing sites worldwide. …”
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58793“…The surface fractal dimension may be useful in ophthalmology for quantifying human lens architectural changes associated with different disease states to further our understanding of disease evolution.…”
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58794por Patthy, Laszlo“…Second, bilaterian ancestors dramatically increased their exon skipping frequencies, likely driven by the interplay between a shift in their genome architectures towards more exon definition and recruitment of frame-preserving exon skipping events to functionally diversify their cell-specific proteomes.” …”
Publicado 2019
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58795por Tsai, Chun-Hao, Hung, Chih-Hung, Kuo, Che-Nan, Chen, Cheng-Yu, Peng, Yu-Ning, Shie, Ming-You“…In conclusion, the Mg–CS/CH coated Ti–6Al–4V scaffolds were able to exhibit and retain pore sizes and their original morphologies and architectures, which significantly affected subsequent hard tissue regeneration. …”
Publicado 2019
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58796por Yamada, Hiroyuki, Mori, Hiroshi, Nakanishi, Yasutomo, Nishikawa, Satoshi, Hashimoto, Yasuaki, Ochi, Yasuo, Tanaka, Makoto, Kawabata, Kazuhito“…Concomitant use of ONO-5334 with MTX reduced architectural joint destruction compared to MTX alone; therefore, ONO-5334 may help to prevent joint destruction in combination with MTX for the treatment of rheumatoid arthritis.…”
Publicado 2019
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58797“…The structural diversities between the two types of architectures can be attributed to the coordination geometry preference of the metal ions (octahedral for Co(2+) and square pyramidal for Cu(2+)). …”
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58798por Wang, Chih-Chieh, Ke, Szu-Yu, Cheng, Chia-Wen, Wang, Yu-Wen, Chiu, Hsiao-Shan, Ko, Yu-Chien, Sun, Ning-Kuei, Ho, Mei-Lin, Chang, Chung-Kai, Chuang, Yu-Chun, Lee, Gene-Hsiang“…These different intriguing architectures indicate that the coordination numbers and geometries of Zn(II) ions, coordination modes of bdc(2−) ligand, and guest molecules play important roles in the construction of MOFs and the formation of the structural topologies and interpenetrations. …”
Publicado 2017
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58799por Bizzego, Andrea, Bussola, Nicole, Chierici, Marco, Maggio, Valerio, Francescatto, Margherita, Cima, Luca, Cristoforetti, Marco, Jurman, Giuseppe, Furlanello, Cesare“…We test three different deep learning architectures (VGG, ResNet, Inception) as feature extractors and three classifiers (a fully connected multilayer, Support Vector Machine and Random Forests) and work with four datasets (5, 10, 20 or 30 classes), for a total of 53, 000 tiles at 512 × 512 resolution. …”
Publicado 2019
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58800por Avramov, Todor Kirilov, Vyenielo, Dan, Gomez-Blanco, Josue, Adinarayanan, Swathi, Vargas, Javier, Si, Dong“…Specifically, we build classification models based on dense artificial neural network (DNN) and 3D convolutional neural network (3D CNN) architectures. The trained models can classify a given 3D cryo-EM density map into one of three resolution levels: high, medium, low. …”
Publicado 2019
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