“…In addition, thousands of eQTLs are associated with alternatively spliced isoforms with complex additive and dominant architectures in heterogeneous stock rats, suggesting a possible mechanism for dominance. …”
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“…However, in disease states, normal architectural patterning can be disrupted by aberrant differentiation. …”
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“…In the context of synthetic bone substitutes, the application of a Triply Periodic Minimum Surface (TPMS) algorithm can yield stable lightweight microarchitectures that, despite their demanding architectural complexity, can be produced by additive manufacturing. …”
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“…Here, we focus on possible structural roles of lncRNAs in the execution of cytokinesis: in particular, we suggest that specific classes of lncRNAs relocate to the midbody to form an architectural scaffold ensuring its proper assembly and function during abscission. …”
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“…Four different deep-learning architectures were evaluated for their performance in classifying bladder cancer, EfficientNetB2, InceptionResNetV2, InceptionV3, and ResNet50V2. …”
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“…ABSTRACT: Stem growth habit is a key architectural trait in many plants that contributes to plant productivity and environmental adaptation. …”
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“…It is important to note that many of the problems we have encountered during sequence finishing reflect unique architectural features of a particular vertebrate's genome, which in some cases may have important functional and/or evolutionary implications. …”
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“…The triple doping of Ce, Tb, and Eu into the LiYF(4) host more effectively enhances the Eu(3+) emission than the core/shell strategies of LiYF(4):Eu(35%)/LiYF(4):Ce(15%), Tb(15%) and LiYF(4):Ce(15%), Tb(15%)/LiYF(4):Eu(35%) architectures. Efficient energy transfer from Ce(3+) to Eu(3+) through Tb(3+) results in three times higher Eu(3+) emission intensity from LiYF(4):Ce(15%), Tb(15%), Eu(1%) nanophosphors compared with LiYF(4):Eu(35%), which contains the optimized Eu(3+) concentration. …”
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“…In summary, our report reaffirms that transcription factors are challenging molecular architectures and that future polyoxometalate chemistry must consider further modification strategies, to address the substantial challenges involved in achieving target selectivity.…”
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“…Also, existing studies of inter-tissue interactions are based on direct gene expression correlations, which can’t distinguish correlations due to common genetic architectures versus biochemical or molecular signal exchange between tissues. …”
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“…RESULTS: We found substantial heritabilities for all three traits and identified candidate genes associated with variation in susceptibility to lead exposure for each phenotype. The genetic architectures that determine variation in sensitivity to lead exposure are highly polygenic. …”
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“…In this study, we aim to investigate network architectural characteristics of a structural covariance network (SCN) in AD, and further to show that the structural covariance connectivity becomes disorganized across the brain regions in AD, while the normal control (NC) subjects maintain more clustered and consistent coordination in cortical atrophy variations. …”
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“…Furthermore, NucTools facilitates the annotation of nucleosome occupancy with other chromatin features like binding of transcription factors or architectural proteins, and epigenetic marks like histone modifications or DNA methylation. …”
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“…Four recurrent neural network (RNN) architectures–as well as a deep neural network and a simple regression model–were proposed to investigate the performance on predicting the activeness of the user under various length-related hyper-parameter settings. …”
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“…BACKGROUND: Transmembrane helices (TMHs) frequently occur amongst protein architectures as means for proteins to attach to or embed into biological membranes. …”
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“…CONCLUSION: The three-dimensional environment of implant surfaces with highly porous and fully interconnected channel and pore architectures can improve cell spreading and accelerate the progress of osseointegration in diabetic mini-pigs.…”
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“…This can result in difficulty in defining the primary site of origin in all but the smallest tumors due to anatomical proximity and architectural distortion. This has led to variation in the reported proportions of resected periampullary cancers. …”
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“…BACKGROUND: Osteoporosis, a common disease worldwide, is characterized by low bone mass and architectural deterioration of bone tissue, leading to enhanced bone fragility and increase in fracture risks. …”
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“…Estimated probabilities for the parental haplotypes were used for multi-allelic QTL analyses on four traits with different underlying genetic architectures. This resulted in the identification of major QTL that were affected by multiple alleles having a differential effect on the phenotype. …”
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“…The degree of intratumoural and peritumoural immune infiltrate was associated with architectural changes in both uninvolved and involved LNs. …”
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