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  1. 3801
    “…EZH2(high) cases displayed high H3K27me3 levels and increased viability suggesting that EZH2 is functional and likely confers a survival advantage to CLL cells. This argument was further supported by siRNA-mediated downmodulation of EZH2 which resulted in increased apoptosis. …”
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    The histone methyltransferase EZH2 as a novel prosurvival factor in clinically aggressive chronic lymphocytic leukemia
  2. 3802
    “…These data strengthen the argument for routine use of age-specific thyroid function reference ranges.…”
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    Serum Thyroid Function, Mortality and Disability in Advanced Old Age: The Newcastle 85+ Study
  3. 3803
    “…The results demonstrate how patients and health care providers used these arguments to negotiate their respective roles in decision-making. …”
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    Patient participation in palliative care decisions: An ethnographic discourse analysis
  4. 3804
    por Magiorkinis, Gkikas, Angelis, Konstantinos, Mamais, Ioannis, Katzourakis, Aris, Hatzakis, Angelos, Albert, Jan, Lawyer, Glenn, Hamouda, Osamah, Struck, Daniel, Vercauteren, Jurgen, Wensing, Annemarie, Alexiev, Ivailo, Åsjö, Birgitta, Balotta, Claudia, Gomes, Perpétua, Camacho, Ricardo J., Coughlan, Suzie, Griskevicius, Algirdas, Grossman, Zehava, Horban, Anders, Kostrikis, Leondios G., Lepej, Snjezana J., Liitsola, Kirsi, Linka, Marek, Nielsen, Claus, Otelea, Dan, Paredes, Roger, Poljak, Mario, Puchhammer-Stöckl, Elizabeth, Schmit, Jean Claude, Sönnerborg, Anders, Staneková, Danica, Stanojevic, Maja, Stylianou, Dora C., Boucher, Charles A.B., Nikolopoulos, Georgios, Vasylyeva, Tetyana, Friedman, Samuel R., van de Vijver, David, Angarano, Gioacchino, Chaix, Marie-Laure, de Luca, Andrea, Korn, Klaus, Loveday, Clive, Soriano, Vincent, Yerly, Sabine, Zazzi, Mauricio, Vandamme, Anne-Mieke, Paraskevis, Dimitrios
    Publicado 2016
    “…Our findings support the argument that epidemic control policies should be global and incorporate political and socioeconomic factors.…”
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    The global spread of HIV-1 subtype B epidemic
  5. 3805
    por Watson, Helen L., Downe, Soo
    Publicado 2017
    “…DATA EXTRACTION AND SYNTHESIS: Standardised data extraction tables were utilised, quality was formally assessed and a line of argument synthesis was developed and tested against the data from the grey literature. …”
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    Discrimination against childbearing Romani women in maternity care in Europe: a mixed-methods systematic review
  6. 3806
    por Aoki, Takuya, Inoue, Machiko
    Publicado 2017
    “…The results of our study might support the argument that patient experience of primary care and the clinical process of preventive care, such as breast cancer screening, are linked. …”
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    Primary care patient experience and cancer screening uptake among women: an exploratory cross-sectional study in a Japanese population
  7. 3807
    “…The findings of this review present a strong argument in favour of prioritizing BPD treatments in reimbursement decisions, both for the affected individual and the family. …”
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    The value of psychological treatment for borderline personality disorder: Systematic review and cost offset analysis of economic evaluations
  8. 3808
    “…The Bethe-Slater (BS) curve describes the relation between the exchange coupling and interatomic distance. Based on a simple argument of orbital overlaps, it successfully predicts the transition from antiferromagnetism to ferromagnetism, when traversing the 3d series. …”
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    The Bethe-Slater curve revisited; new insights from electronic structure theory
  9. 3809
    “…We found that it decreases consistency in the decision patterns, thus providing an argument for algorithmic decision-making in road traffic. …”
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    Using Virtual Reality to Assess Ethical Decisions in Road Traffic Scenarios: Applicability of Value-of-Life-Based Models and Influences of Time Pressure
  10. 3810
    “…Abdul-Ghani and DeFronzo provide their argument that a treatment approach for type 2 diabetes based upon correcting the underlying pathophysiological abnormalities responsible for the development of hyperglycemia provides the best therapeutic strategy. …”
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    Is It Time to Change the Type 2 Diabetes Treatment Paradigm? Yes! GLP-1 RAs Should Replace Metformin in the Type 2 Diabetes Algorithm
  11. 3811
    “…Our analysis indicates that the arguments for mandatory review substantially outweigh the arguments to the contrary. …”
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    Ethics review in compassionate use
  12. 3812
    “…CONCLUSIONS: This study documents that a decline in FS precedes incidence of CVD‐related hospitalization by at least 2 years, providing a strong argument for routine preventative assessment of FS among older adults.…”
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    Cardiovascular Disease and Patterns of Change in Functional Status Over 15 Years: Findings From the Atherosclerosis Risk in Communities (ARIC) Study
  13. 3813
    “…Simulation results demonstrate proof of concept for how the narrative construction model supports multiple successive levels of meaning creation which allows the system to learn about the intentionality of mental states, and argument substitution which allows extensions to metaphorical language and analogical problem solving. …”
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    Narrative Constructions for the Organization of Self Experience: Proof of Concept via Embodied Robotics
  14. 3814
    “…CONCLUSIONS: The quality of palliative care as experienced from the relatives’ perspective is highest when the patient dies at home or in a hospice. This is an argument for letting people die at home, if they so wish, as far as possible and feasible.…”
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    Relatives’ perceived quality of palliative care: comparisons between care settings in which patients die
  15. 3815
    “…This re-analysis provides additional support for the argument that experimental standardization and validation of pharmacogenomic response will be necessary to advance the broad use of large pharmacogenomic screens.…”
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    Revisiting inconsistency in large pharmacogenomic studies
  16. 3816
    “…In this review, we put forward the argument that the likelihood of artificial agents being perceived as social companions can be increased by designing them in a way that they are perceived as intentional agents that activate areas in the human brain involved in social-cognitive processing. …”
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    Robots As Intentional Agents: Using Neuroscientific Methods to Make Robots Appear More Social
  17. 3817
    “…These data support the argument that during the evolutionary process, mammals incorporated not only similar ERV sequences, but also ERVs unique to individual species. …”
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    Novel endogenous retrovirus-derived transcript expressed in the bovine placenta is regulated by WNT signaling
  18. 3818
    “…These data contradict the argument that patients in managed care plans have limited healthcare access, but underline the central role of PCPs as coordinator of care.…”
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    Referral determinants in Swiss primary care with a special focus on managed care
  19. 3819
    “…CONCLUSIONS: Synthesised, although there was no level 1 evidence, our review found a consistently positive association held between culture and outcomes across multiple studies, settings and countries. This supports the argument in favour of activities that promote positive cultures in order to enhance outcomes in healthcare organisations.…”
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    Association between organisational and workplace cultures, and patient outcomes: systematic review
  20. 3820
    por Skinner, Rasjid, Kaplick, Paul M
    Publicado 2017
    “…We add new evidence to the argument that post-traumatic stress disorder in its current conceptualisation does not adequately account, not only for ethnocultural variation but also for historical variation in stress responses within the same culture.…”
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    Cultural shift in mental illness: a comparison of stress responses in World War I and the Vietnam War
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