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  1. 3881
    “…In the past decade, tremendous advances have taken place in which scientists and physicians have begun to harness the power of the immune system to create immunotherapies to fight cancer, inflammatory syndromes and autoimmune diseases. Thus, the argument can be made that training individuals in the field of immunology is becoming increasingly important. …”
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    Out of the Curricular Shadows: Revolutionizing Undergraduate Immunology Education
  2. 3882
    “…We also address the argument that the limited amount of variance explained by the duration of practice necessarily implies an important role of genetic factors, and we report that genetic effects have so far accounted for remarkably small amounts of variance – with exception of genetic influences of height and body size. …”
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    Deliberate Practice and Proposed Limits on the Effects of Practice on the Acquisition of Expert Performance: Why the Original Definition Matters and Recommendations for Future Research
  3. 3883
    “…MAIN BODY: The main argument for including conference abstracts in systematic reviews is that abstracts with positive results are preferentially published, and published sooner, as full-length articles compared with other abstracts. …”
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    How should systematic reviewers handle conference abstracts? A view from the trenches
  4. 3884
    “…These moments feature different degrees of “crystallization” of the idea; from gestures, a sketch, a short written note, oral explanations to a final spelled-out written argument. For this contribution, we re-analyze the material, asking how the idea gets formed during the thinking process and how it reaches a tangible form, which is understandable both for the thinker and for other persons. …”
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    How Ideas Come Into Being: Tracing Intertextual Moments in Grades of Objectification and Publicness
  5. 3885
    por Huan, Lu, Qin, Fei, Wu, Yin
    Publicado 2019
    “…Concerns about the effect of epinephrine for out-of-hospital cardiac arrest were controversial and called for a higher argument to determine whether the effects of epinephrine is safe and effective for shor and long terms outcomes. …”
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    Effects of epinephrine for out-of-hospital cardiac arrest: A systematic review and meta-analysis of randomized controlled trials
  6. 3886
    “…The up-regulation of TSP1, inhibition of cell proliferation, migration and tubulogenesis provides support to the argument that the combination of metformin and 2DG may prove to be an appropriate anti-proliferative and anti-angiogenic therapeutic strategy for the treatment of some cancers.…”
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    Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy
  7. 3887
    “…Many Tdp1 substrates are generated by chemotherapeutics linking Tdp1 to cancer drug resistance, making a compelling argument to develop small molecules that target Tdp1 as potential novel therapeutic agents. …”
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    Targeting Tyrosyl-DNA phosphodiesterase I to enhance toxicity of phosphodiester linked DNA-adducts
  8. 3888
    por Aaltola, Elisa
    Publicado 2019
    “…After discussing “nudging” as an implication of the descriptive approach, the paper supports the prescriptive perspective and “the cultivation argument”. The claim is that contemporary research on the contradictions concerning attitudes toward other animals would greatly benefit from paying more attention to the value-laden mental factors underlying moral agency.…”
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    The Meat Paradox, Omnivore’s Akrasia, and Animal Ethics
  9. 3889
    “…Our findings represent an additional argument to promote physical activity to patients over 60 years old. …”
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    Association between physical activity and Nocturnal Leg Cramps in patients over 60 years old: a case-control study
  10. 3890
    por Gutfreund, Yoram
    Publicado 2020
    “…I therefore call on policy-makers to reconsider the placement of HBA jargon in the guidelines and support an alternative guideline that is both practical and ethical. I based this argument on theoretical considerations but also on my years of experience as head of an Institutional Animal Care and Use Committee (IACUC) and as a representative in the Israeli Council of Animal Experimentation. …”
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    Harm-Benefit Analysis May Not Be the Best Approach to Ensure Minimal Harms and Maximal Benefits of Animal Research—Alternatives Should Be Explored
  11. 3891
    “…DISCUSSION: This study presents a compelling argument for further research regarding the use of IV iron in elderly patients undergoing surgery for a hip fracture. …”
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    Intravenous Iron May Improve Outcomes in Elderly Patients With Operative Hip Fractures
  12. 3892
    “…It may also contribute to the concept of the human body as a superorganism where the microbiome is part of the whole organism, as can be seen with mitochondria which existed as microbes prior to becoming organelles in eukaryotic cells of multicellular organisms over time. A similar argument can now be made in regard to normal intestinal flora, living in symbiosis within the host. …”
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    Infectome: A platform to trace infectious triggers of autoimmunity
  13. 3893
    por Parris, George E.
    Publicado 2007
    “…Both major camps in the argument presume that humans are normally free of such viruses and assume that once the simian virus was transmitted, it immediately infected some T-cells and caused the release of toxic agents that killed off bystander (uninfected) T-cells resulting in AIDS. …”
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    AIDS: Caused by development of resistance to drugs in a non-target intracellular parasite
  14. 3894
    “…Evidence of a robust inverse relationship between the frequency and magnitude of repeated head impacts and disturbed brain network function is needed to strengthen an argument for causality. In pursuing such a relationship, we used cap-worn inertial sensors to measure the frequency and magnitude of head impacts sustained by eighteen intercollegiate water polo athletes monitored over a single season of play. …”
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    A Dose Relationship Between Brain Functional Connectivity and Cumulative Head Impact Exposure in Collegiate Water Polo Players
  15. 3895
    “…The accumulation ratios based on AUC(0‐24h) range from 0.90 to 1.03, supporting this argument. All subjects receiving ≥60 mg dutogliptin yielded a maximum DPP‐IV inhibition >90%. …”
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    Safety, tolerability, pharmacokinetics and pharmacodynamics of parenterally administered dutogliptin: A prospective dose‐escalating trial
  16. 3896
    “…This review also carefully explores the argument that ruminant trans fatty acids have differential effects from industrial trans fatty acids. …”
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    Mechanisms of Action of trans Fatty Acids
  17. 3897
    “…There is, however, a compelling argument for the development of compartmentalised systems whereby the release, stability and incorporation environment of the different drugs may be tailored. …”
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    A Portable Device for the Generation of Drug-Loaded Three-Compartmental Fibers Containing Metronidazole and Iodine for Topical Application
  18. 3898
    por Bunni, J., Coffey, J. C., Kalady, M. F.
    Publicado 2020
    “…Whilst this remains a suggestion only, it would explain the histological independence of tumour deposits and why a greater mesenterectomy could be associated with benefits in survival. If this argument holds, it follows that resectional surgery for digestive organ malignancy is not surgery of the organ itself (or lymphatics only), but also that of the contiguous mesentery.…”
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    Resectional surgery for malignant disease of abdominal digestive organs is not surgery of the organ itself, but also that of the mesenteric organ
  19. 3899
    “…While filters for washing-machines are sold to consumers with the argument they will reduce the emissions of fibres from clothes to the environment, there is insufficient scientific peer-reviewed evidence assessing their ability to retain fibres from washed clothes and reduce environmental contamination. …”
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    Pore-size and polymer affect the ability of filters for washing-machines to reduce domestic emissions of fibres to sewage
  20. 3900
    “…The COVID-19 pandemic has highlighted the falsity of any assumption that the global North has all the expertise and solutions to tackle global challenges, and has further highlighted the need for multi-directional learning and transformation in all countries towards a more sustainable and equitable world. We illustrate our argument for a global development paradigm by examining the implications of the COVID-19 pandemic across four themes or 'vignettes': global value chains, digitalisation, debt, and climate change. …”
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    COVID-19 and the case for global development
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