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26161por Morel, Thomas, Arickx, Francis, Befrits, Gustaf, Siviero, Paolo, van der Meijden, Caroline, Xoxi, Entela, Simoens, Steven“…Antineoplastic agents were the primary targets of MEAs. 55% of the identified MEAs were performance-based risk-sharing arrangements; the other 45% were financial-based. Nine of these 26 OMPs were subject to MEAs in two or three different countries, resulting in 24 MEAs. 60% of identified MEAs focused on conditions whose prevalence is less than 1 per 10,000. …”
Publicado 2013
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26162por Patel, Anamika, Vought, Valarie E., Swatkoski, Stephen, Viggiano, Susan, Howard, Benny, Dharmarajan, Venkatasubramanian, Monteith, Kelsey E., Kupakuwana, Gillian, Namitz, Kevin E., Shinsky, Stephen A., Cotter, Robert J., Cosgrove, Michael S.“…We also report that MLL1 methylates Ash2L in the absence of histone H3, but only when assembled within a complex with WDR5 and RbBP5, suggesting a restraint for the architectural arrangement of subunits within the complex. Using MLL1 and Ash2L automethylation reactions as probes for histone binding, we observed that both automethylation reactions are significantly inhibited by stoichiometric amounts of unmethylated histone H3, but not by histones previously mono-, di-, or trimethylated at H3K4. …”
Publicado 2014
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26163“…P450s with the same gene structure were found tandemly arranged in the genomes of selected fungi. This clearly suggests that extensive gene duplications, particularly tandem gene duplications, led to the enrichment of selective P450 families in basidiomycetes. …”
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26164“…The origin of the tribe is firmly based in the Southern Hemisphere with the arrangement of Neotropical and Afrotropical taxa as the most basal clades suggesting a Gondwana vicariance origin. …”
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26165por Katz, David A, Paez, Monica W, Reisinger, Heather S, Gillette, Meghan T, Weg, Mark W Vander, Titler, Marita G, Nugent, Andrew S, Baker, Laurence J, Holman, John E, Ono, Sarah S“…The aim of this study was to characterize emergency physicians’ (EPs) and nurses’ (ENs) perceptions of cessation counseling and to identify barriers and facilitators to implementation of the 5 A’s framework (Ask-Advise-Assess-Assist-Arrange) in the ED. METHODS: We conducted semi-structured, face-to-face interviews of 11 EPs and 19 ENs following a pre-post implementation trial of smoking cessation guidelines in two study EDs. …”
Publicado 2014
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26166“…Increasingly, the electronic health record (EHR) has dominated the healthcare arena and the maternity general practice shared-care arrangement seems to have adopted this initiative. A systematic review was conducted to determine perspectives of the PHR and the EHR with regards to data completeness; experiences of users and integration of care between women and health care providers. …”
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26167por Park, Soo-Young, Ludwig, Michael Z., Tamarina, Natalia A., He, Bin Z., Carl, Sarah H., Dickerson, Desiree A., Barse, Levi, Arun, Bharath, Williams, Calvin L., Miles, Cecelia M., Philipson, Louis H., Steiner, Donald F., Bell, Graeme I., Kreitman, Martin“…Eye imaginal discs exhibit defects in both the structure and the arrangement of ommatidia. In the wing, expression of hINS(C96Y) leads to ectopic expression of veins and mechano-sensory organs, indicating disruption of wild-type signaling processes regulating cell fates. …”
Publicado 2014
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26168“…They may cause significant damage to the closely arranged structures in this region, and the bullet’s trajectory can be very difficult to determine. …”
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26169“…Based on the minimum inhibitory concentration and minimum bactericidal concentration values, the most effective 10 plants against uropathogens could be arranged in decreasing order as follows: C. tora > A. acuminata > Schleichera oleosa > Pterocarpus santalinus > Eugenia jambolana > Bridelia retusa > Mimusops elengi > Stereospermum kunthianum > Tectona grandis > Anthocephalus cadamba. …”
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26170“…CONCLUSION: Living arrangement, educational status of parents, family connectedness, alcohol consumption and khat-chewing were the major predictors of risky sexual behavior. …”
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26171por Chaterji, Somali, Lam, Christoffer H., Ho, Derek S., Proske, Daniel C., Baker, Aaron B.“…The spread area of the S1KO cells was found to be greater than WT cells, with a corresponding increase in focal adhesion formation, Src phosphorylation, and alterations in actin cytoskeletal arrangement. In addition, S1KO led to increased S6RP phosphorylation and decreased AKT and PKC-α phosphorylation. …”
Publicado 2014
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26172“…Randomisation will be undertaken using a computer-generated sequence in a 1:1 ratio to the two treatments arranged in permuted blocks with stratification by age, sex, and ethnicity. …”
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26173por Ince, Abdulkadir, Ozucelik, Dogac Niyazi, Avci, Akkan, Nizam, Ozgur, Dogan, Halil, Topal, Mehmet Ali“…According to the etiology of the pneumothorax, study groups were arranged like spontaneous pneumothorax and traumatic pneumothorax. …”
Publicado 2013
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26174Diagnostic and Prognostic Implications of a Serum miRNA Panel in Oesophageal Squamous Cell Carcinomapor Wu, Caiyun, Wang, Cheng, Guan, Xiaocui, Liu, Yuxiu, Li, Demin, Zhou, Xiaojun, Zhang, Yanni, Chen, Xi, Wang, Junjun, Zen, Ke, Zhang, Chen-Yu, Zhang, Chunni“…Markedly upregulated miRNAs in ESCC and some miRNAs reported to be differently expressed in ESCC tissue were then validated individually by RT-qPCR in another 83 patients and 83 controls arranged in two phases. The changes of the selected miRNAs during the esophagectomy and their prognostic value were examined. …”
Publicado 2014
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26175por Zimper, Ulrike, Aaltonen, Jaakko, Krauel-Goellner, Karen, Gordon, Keith C., Strachan, Clare J., Rades, Thomas“…Drugs with different molecular arrangements may exhibit altered properties such as solubility and dissolution rate and, therefore, process induced solid state modifications need to be monitored. …”
Publicado 2010
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26176por Rodríguez, Fabián A., Liu, Zhi, Lin, Chin H., Ding, Shuang, Cai, Yuqin, Kolbanovskiy, Alexander, Kolbanovskiy, Marina, Amin, Shantu, Broyde, Suse, Geacintov, Nicholas E.“…[Image: see text] The dimensions and arrangements of aromatic rings (topology) in adducts derived from the reactions of polycyclic aromatic hydrocarbon (PAH) diol epoxide metabolites with DNA influence the distortions and stabilities of double-stranded DNA, and hence their recognition and processing by the human nucleotide excision repair (NER) system. …”
Publicado 2014
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26177por Thomson, Jennifer S, Anderson, Katrina, Haesler, Emily, Barnard, Amanda, Glasgow, Nicholas“…A practice environment where there is a strong teaching culture, enjoyment of learning, and flexible learning methods, as well as learning spaces and organised teaching arrangements, all contribute to positive learning from a learners’ perspective. …”
Publicado 2014
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26178por Shah, N. Jon, Herzog, Hans, Weirich, Christoph, Tellmann, Lutz, Kaffanke, Joachim, Caldeira, Liliana, Kops, Elena Rota, Qaim, Syed M., Coenen, Heinz H., Iida, Hidehiro“…Previous papers have reported this either by simulation or experiment with simple sources and detector arrangements. Here, we extend those studies using a realistic brain phantom in a recently installed MR-PET system comprising a 9.4 T MRI-scanner and an APD-based BrainPET insert in the magnet bore. …”
Publicado 2014
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26179por Sonier, Marcus, Gete, Ermias, Herbert, Chris, McKenzie, Michael, Murphy, James, Moiseenko, Vitali“…METHODS: Thirty-one AVM patients previously treated with 3DCRT were replanned in a commercial treatment planning system using 3DCRT and static gantry IMRT with identical beam arrangements. The radiotherapy planning metrics analyzed included AVM volume, diameter, and volume to surface area ratio. …”
Publicado 2014
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26180por Benoit, Joshua B., Attardo, Geoffrey M., Michalkova, Veronika, Krause, Tyler B., Bohova, Jana, Zhang, Qirui, Baumann, Aaron A., Mireji, Paul O., Takáč, Peter, Denlinger, David L., Ribeiro, Jose M., Aksoy, Serap“…The genes encoding mgp2–10 are organized on a 40 kb syntenic block in the tsetse genome, have similar exon-intron arrangements, and share regions of amino acid sequence similarity. …”
Publicado 2014
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