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  1. 118681
    “…Whole cell antigen for O. tsutsugamushi (OT-WCA) was prepared by heat inactivation of Karp-strain bacteria. Rhesus macaques were infected intradermally with O. tsutsugamushi. …”
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    Strong interferon-gamma mediated cellular immunity to scrub typhus demonstrated using a novel whole cell antigen ELISpot assay in rhesus macaques and humans
  2. 118682
    “…METHODS: To assess the impact of PCV13 introduction, identify emerging serotypes, and assess risk factors for carriage, nasopharyngeal swabs and information on demographic characteristics, health, medication and living conditions from Aboriginal children and adults across WA from August 2008 to November 2014 were collected. Bacteria were cultured using selective media and pneumococcal isolates were serotyped by Quellung reaction. …”
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    Predictors of pneumococcal carriage and the effect of the 13-valent pneumococcal conjugate vaccination in the Western Australian Aboriginal population
  3. 118683
    “…Prevalence and resistance profiles of bacteria will be assessed using throat and sputum samples collected at baseline and 4-week follow-up. …”
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    General practitioner use of a C-reactive protein point-of-care test to help target antibiotic prescribing in patients with acute exacerbations of chronic obstructive pulmonary disease (the PACE study): study protocol for a randomised controlled trial
  4. 118684
    “…METHODS: A total of 744 organisms collected from 55 hospitals in 2011–2016 were evaluated, including 463 S. aureus, 88 coagulase-negative staphylococci (CoNS), 104 β-haemolytic streptococci (BHS), 60 E. faecalis, and 29 viridans group streptococci (VGS). Bacteria were identified by standard algorithms and MALDI-TOF-MS. …”
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    Antimicrobial Activity of Dalbavancin and Comparator Agents Tested against Gram-Positive Clinical Isolates Causing Bone and Joint Infections in United States (US) Medical Centers (2011–2016)
  5. 118685
    “…Antimicrobial activity (3 bacteria, 6 yeasts, and 2 fungi) was evaluated by the dilution method with resazurin (2048, 512, 128, 32, and 8 μg/mL). …”
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    Bioassay-guided In vitro Study of the Antimicrobial and Cytotoxic Properties of the Leaves from Excoecaria Lucida Sw
  6. 118686
    “…ESBL-screen positive Escherichia coli isolates (ESBL+) showed a decreasing trend from 67.5% in 2012 to 58.9% in 2014 of all Escherichia coli isolates and the percentage of ESBL+ Klebsiella pneumoniae isolates also decreased from 2012 through 2014 (40.4% to 26.6%), which was due to reduced percentages of ESBL+ isolates in HA IAIs for both bacteria. The overall susceptibilities of all 5160 IAI isolates were 87.53% to amikacin (AMK), 78.12% to piperacillin-tazobactam (TZP) 81.41% to imipenem (IMP) and 73.12% to ertapenem (ETP). …”
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    Update of incidence and antimicrobial susceptibility trends of Escherichia coli and Klebsiella pneumoniae isolates from Chinese intra-abdominal infection patients
  7. 118687
    “…We recruited adults with a positive blood culture yielding pathogenic bacteria identified while in ICU. We excluded patients with severe immunosuppression, foci of infection with an established requirement for prolonged treatment, single cultures with potential contaminants, or cultures yielding Staphylococcus aureus or fungi. …”
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    7 versus 14 days of antibiotic treatment for critically ill patients with bloodstream infection: a pilot randomized clinical trial
  8. 118688
    “…BACKGROUND: Enhancing caspase-1 activation in macrophages is helpful for the clearance of intracellular bacteria in mice. Our previous studies have shown that EscI, an inner rod protein of type III system in E. coli can enhance caspase-1 activation. …”
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    Immunization with recombinant Salmonella expressing SspH2-EscI protects mice against wild type Salmonella infection
  9. 118689
    “…In addition, comparison of the effects of the IM across studies was difficult due to lack of specific analysis/description of the bacteria involved. Considerable animal-derived data exist, but experience suggests that care must be taken when extrapolating these results to humans. …”
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    Systematic review of the effects of the intestinal microbiota on selected nutrients and non-nutrients
  10. 118690
    “…Ascending infections caused by sexually transmitted bacteria or urinary tract pathogens represent the most frequent aetiology of epididymo-orchitis, but viral, haematogenous dissemination is also a contributory factor. …”
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    Infectious, inflammatory and ‘autoimmune’ male factor infertility: how do rodent models inform clinical practice?
  11. 118691
    “…The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1–31·8; I(2) =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8–10·7; I(2) =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6–36·8; I(2) =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3–47·6; I(2) =98%) than in other migrant groups (6·6%, 1·8–11·3; I(2) =92%). …”
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    Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis
  12. 118692
    por Saha, Samir K, Schrag, Stephanie J, El Arifeen, Shams, Mullany, Luke C, Shahidul Islam, Mohammad, Shang, Nong, Qazi, Shamim A, Zaidi, Anita K M, Bhutta, Zulfiqar A, Bose, Anuradha, Panigrahi, Pinaki, Soofi, Sajid B, Connor, Nicholas E, Mitra, Dipak K, Isaac, Rita, Winchell, Jonas M, Arvay, Melissa L, Islam, Maksuda, Shafiq, Yasir, Nisar, Imran, Baloch, Benazir, Kabir, Furqan, Ali, Murtaza, Diaz, Maureen H, Satpathy, Radhanath, Nanda, Pritish, Padhi, Bijaya K, Parida, Sailajanandan, Hotwani, Aneeta, Hasanuzzaman, M, Ahmed, Sheraz, Belal Hossain, Mohammad, Ariff, Shabina, Ahmed, Imran, Ibne Moin, Syed Mamun, Mahmud, Arif, Waller, Jessica L, Rafiqullah, Iftekhar, Quaiyum, Mohammad A, Begum, Nazma, Balaji, Veeraraghavan, Halen, Jasmin, Nawshad Uddin Ahmed, A S M, Weber, Martin W, Hamer, Davidson H, Hibberd, Patricia L, Sadeq-ur Rahman, Qazi, Mogan, Venkat Raghava, Hossain, Tanvir, McGee, Lesley, Anandan, Shalini, Liu, Anran, Panigrahi, Kalpana, Abraham, Asha Mary, Baqui, Abdullah H
    Publicado 2018
    “…Furthermore, the predominance of atypical bacteria we found and high incidence of respiratory syncytial virus indicated that changes in management strategies for treatment and prevention are needed. …”
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    Causes and incidence of community-acquired serious infections among young children in south Asia (ANISA): an observational cohort study
  13. 118693
    “…There were no significant changes in the relative abundance of bacteria in the genera Bifidobacterium (SMD 1.29% [95% CI −4.45, 7.03], I(2) = 33%, p > 0.05), Roseburia (SMD −0.85% [95% CI −2.91, 1.21], I(2) = 79%, p > 0.05) or Lactobacillus (SMD 0.04% [95% CI −0.01, 0.09], I(2) = 0%, p > 0.05) when comparing dietary interventions with comparator groups. …”
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    Systematic review assessing the effectiveness of dietary intervention on gut microbiota in adults with type 2 diabetes
  14. 118694
    por Rogawski, Elizabeth T, Liu, Jie, Platts-Mills, James A, Kabir, Furqan, Lertsethtakarn, Paphavee, Siguas, Mery, Khan, Shaila S, Praharaj, Ira, Murei, Arinao, Nshama, Rosemary, Mujaga, Buliga, Havt, Alexandre, Maciel, Irene A, Operario, Darwin J, Taniuchi, Mami, Gratz, Jean, Stroup, Suzanne E, Roberts, James H, Kalam, Adil, Aziz, Fatima, Qureshi, Shahida, Islam, M Ohedul, Sakpaisal, Pimmada, Silapong, Sasikorn, Yori, Pablo P, Rajendiran, Revathi, Benny, Blossom, McGrath, Monica, Seidman, Jessica C, Lang, Dennis, Gottlieb, Michael, Guerrant, Richard L, Lima, Aldo A M, Leite, Jose Paulo, Samie, Amidou, Bessong, Pascal O, Page, Nicola, Bodhidatta, Ladaporn, Mason, Carl, Shrestha, Sanjaya, Kiwelu, Ireen, Mduma, Estomih R, Iqbal, Najeeha T, Bhutta, Zulfiqar A, Ahmed, Tahmeed, Haque, Rashidul, Kang, Gagandeep, Kosek, Margaret N, Houpt, Eric R
    Publicado 2018
    “…Diarrhoeal episodes attributed to bacteria and parasites, but not viruses, were associated with small decreases in length after 3 months and at age 2 years. …”
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    Use of quantitative molecular diagnostic methods to investigate the effect of enteropathogen infections on linear growth in children in low-resource settings: longitudinal analysis of results from the MAL-ED cohort study
  15. 118695
    “…Virus–virus and virus–bacteria co-infections are rare. Further studies are needed to establish causality between FWS and viremia. …”
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    2569. High Incidence of Enterovirus, HHV6, Parechovirus and Adenovirus Blood Viremia in Children 0 to 3 Years Old Presenting With Fever Without Source
  16. 118696
    “…BACKGROUND: Ceftriaxone–sulbactam–EDTA (CSE) is a novel combination being developed to treat serious infections caused by Gram-negative bacteria. In vitro molecular biology studies have shown that the addition of EDTA in the combination helps to prevent horizontal gene transfer during conjugation by chelating the divalent magnesium ions (Mg(2+)) required for the activity of DNA relaxases enzyme. …”
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    1984. Ceftriaxone-Sulbactam-EDTA vs. Meropenem: Analysis of Failed Patients With Assessment of MIC Increases and Changes in Genotypic Profile in PLEA (a Phase 3, Randomized, Double-Blind Clinical Trial in Adults With Complicated Urinary Tract Infections or Acute Pyelonephritis)
  17. 118697
    “…Cell-free plasma DNA was prepared and sequenced in a CLIA/CAP laboratory, human reads excluded, and remaining sequences aligned to a curated pathogen database that includes bacteria, viruses, fungi and parasites. Positive agreement (PA) was defined as KT identification of ≥1 isolate also seen by blood culture (BC). …”
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    2294. Evaluation of the Karius Plasma Next-Generation Sequencing Cell-free Pathogen DNA Test to Determine the Etiology of Infection and Impact on Anti-Microbial Management in Patients with Severe Neutropenia and Fever
  18. 118698
    “…BACKGROUND: Cefiderocol (S-649266, CFDC) is a novel siderophore cephalosporin with activity against a wide variety of Gram-negative bacteria including carbapenem-resistant strains. We previously reported that CFDC is efficiently transported into Pseudomonas aeruginosa via iron transporter PiuA. …”
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    696. Mechanism of Cefiderocol high MIC mutants obtained in non-clinical FoR studies
  19. 118699
    “…Tests that detect E histolytica more accurately are needed, particularly in countries where concomitant infection with other bacteria and parasites is common. 11 April 2019 Up to date All studies incorporated from most recent search All eligible published studies found in the last search (22 Mar, 2018) were included and two ongoing studies have been identified (see 'Characteristics of ongoing studies' section)…”
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    Antiamoebic drugs for treating amoebic colitis
  20. 118700
    “…We knocked down AgdsxF expression in larvae through oral delivery of double stranded RNA (dsRNA) produced by bacteria and observed its effects in adults. RESULTS: Our results show that feeding of AgdsxF dsRNA can effectively reduce (> 66%) the mRNA of female dsx transcript and that there is a concomitant reduction in the number of female larvae that achieve adulthood. …”
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    Downregulation of female doublesex expression by oral-mediated RNA interference reduces number and fitness of Anopheles gambiae adult females
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