The ER folding sensor UGGT1 acts on TAPBPR-chaperoned peptide-free MHC I

por Sagert, Lina, Winter, Christian, Ruppert, Ina, Zehetmaier, Maximilian, Thomas, Christoph, Tampé, Robert
Publicado 2023

A back-door insight into the modulation of Src kinase activity by the polyamine spermidine

por Rossini, Sofia, Gargaro, Marco, Scalisi, Giulia, Bianconi, Elisa, Ambrosino, Sara, Panfili, Eleonora, Volpi, Claudia, Orabona, Ciriana, Macchiarulo, Antonio, Fallarino, Francesca, Mondanelli, Giada
Publicado 2023

MYC overrides HIF-1α to regulate proliferating primary cell metabolism in hypoxia

por Copeland, Courtney A, Olenchock, Benjamin A, Ziehr, David, McGarrity, Sarah, Leahy, Kevin, Young, Jamey D, Loscalzo, Joseph, Oldham, William M
Publicado 2023

Regulation of Long Noncoding RNA NEAT1/miR-320a/HIF-1α Competitive Endogenous RNA Regulatory Network in Diabetic Retinopathy

por Zhu, Xiaodan, Wang, Yan, Cheng, Lei, Kuang, Hongyu
Publicado 2023

How nearby nutrients shape tumor growth

por Kalaany, Nada
Publicado 2023

Human Lacrimal Gland Derived Mesenchymal Stem Cells – Isolation, Propagation, and Characterization

por Jaffet, Jilu, Mohanty, Aparna, Veernala, Induvahi, Singh, Swati, Ali, Mohammad Javed, Basu, Sayan, Vemuganti, Geeta K., Singh, Vivek
Publicado 2023

A critical evaluation of protein kinase regulation by activation loop autophosphorylation

por Reinhardt, Ronja, Leonard, Thomas A
Publicado 2023

Phosphorylation of tyrosine 90 in SH3 domain is a new regulatory switch controlling Src kinase

por Koudelková, Lenka, Pelantová, Markéta, Brůhová, Zuzana, Sztacho, Martin, Pavlík, Vojtěch, Pánek, Dalibor, Gemperle, Jakub, Talacko, Pavel, Brábek, Jan, Rösel, Daniel
Publicado 2023

Conformational regulation and target-myristoyl switch of calcineurin B homologous protein 3

por Becker, Florian, Fuchs, Simon, Refisch, Lukas, Drepper, Friedel, Bildl, Wolfgang, Schulte, Uwe, Liang, Shuo, Heinicke, Jonas Immanuel, Hansen, Sierra C, Kreutz, Clemens, Warscheid, Bettina, Fakler, Bernd, Mymrikov, Evgeny V, Hunte, Carola
Publicado 2023

Allosteric activation or inhibition of PI3Kγ mediated through conformational changes in the p110γ helical domain

por Harris, Noah J, Jenkins, Meredith L, Nam, Sung-Eun, Rathinaswamy, Manoj K, Parson, Matthew AH, Ranga-Prasad, Harish, Dalwadi, Udit, Moeller, Brandon E, Sheeky, Eleanor, Hansen, Scott D, Yip, Calvin K, Burke, John E
Publicado 2023

Structural insight into guanylyl cyclase receptor hijacking of the kinase–Hsp90 regulatory mechanism

por Caveney, Nathanael A, Tsutsumi, Naotaka, Garcia, K Christopher
Publicado 2023

p38γ and p38δ modulate innate immune response by regulating MEF2D activation

por Escós, Alejandra, Diaz-Mora, Ester, Pattison, Michael, Fajardo, Pilar, González-Romero, Diego, Risco, Ana, Martín-Gómez, José, Bonneil, Éric, Sonenberg, Nahum, Jafarnejad, Seyed Mehdi, Sanz-Ezquerro, Juan José, Ley, Steven C, Cuenda, Ana
Publicado 2023

Structure of the connexin-43 gap junction channel in a putative closed state

por Qi, Chao, Acosta Gutierrez, Silvia, Lavriha, Pia, Othman, Alaa, Lopez-Pigozzi, Diego, Bayraktar, Erva, Schuster, Dina, Picotti, Paola, Zamboni, Nicola, Bortolozzi, Mario, Gervasio, Francesco Luigi, Korkhov, Volodymyr M
Publicado 2023

Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice

por Overman, Jeroen, Fontaine, Frank, Moustaqil, Mehdi, Mittal, Deepak, Sierecki, Emma, Sacilotto, Natalia, Zuegg, Johannes, Robertson, Avril AB, Holmes, Kelly, Salim, Angela A, Mamidyala, Sreeman, Butler, Mark S, Robinson, Ashley S, Lesieur, Emmanuelle, Johnston, Wayne, Alexandrov, Kirill, Black, Brian L, Hogan, Benjamin M, De Val, Sarah, Capon, Robert J, Carroll, Jason S, Bailey, Timothy L, Koopman, Peter, Jauch, Ralf, Cooper, Matthew A, Gambin, Yann, Francois, Mathias
Publicado 2023

The intrinsically disordered cytoplasmic tail of a dendrite branching receptor uses two distinct mechanisms to regulate the actin cytoskeleton

por Kramer, Daniel A, Narvaez-Ortiz, Heidy Y, Patel, Urval, Shi, Rebecca, Shen, Kang, Nolen, Brad J, Roche, Julien, Chen, Baoyu
Publicado 2023

Investigating the composition and recruitment of the mycobacterial ImuA′–ImuB–DnaE2 mutasome

por Gessner, Sophia, Martin, Zela Alexandria-Mae, Reiche, Michael A, Santos, Joana A, Dinkele, Ryan, Ramudzuli, Atondaho, Dhar, Neeraj, de Wet, Timothy J, Anoosheh, Saber, Lang, Dirk M, Aaron, Jesse, Chew, Teng-Leong, Herrmann, Jennifer, Müller, Rolf, McKinney, John D, Woodgate, Roger, Mizrahi, Valerie, Venclovas, Česlovas, Lamers, Meindert H, Warner, Digby F
Publicado 2023

Oxidoreductases and metal cofactors in the functioning of the earth

por Hay Mele, Bruno, Monticelli, Maria, Leone, Serena, Bastoni, Deborah, Barosa, Bernardo, Cascone, Martina, Migliaccio, Flavia, Montemagno, Francesco, Ricciardelli, Annarita, Tonietti, Luca, Rotundi, Alessandra, Cordone, Angelina, Giovannelli, Donato
Publicado 2023

The Role of Adipsin, Complement Factor D, in the Pathogenesis of Graves’ Orbitopathy

por Byeon, Hyeong Ju, Chae, Min Kyung, Ko, JaeSang, Lee, Eun Jig, Kikkawa, Don O., Jang, Sun Young, Yoon, Jin Sook
Publicado 2023

Intrinsic Disorder in the Human Tear Proteome

por Taylor Gonzalez, David J., Djulbegovic, Mak, Antonietti, Michael, Cordova, Matthew, Dayhoff, Guy W., Mattes, Robby, Galor, Anat, Uversky, Vladimir N., Karp, Carol L.
Publicado 2023

Saccharomyces cerevisiae DJ-1 paralogs maintain genome integrity through glycation repair of nucleic acids and proteins

por Susarla, Gautam, Kataria, Priyanka, Kundu, Amrita, D'Silva, Patrick
Publicado 2023