The Axin scaffold protects the kinase GSK3β from cross-pathway inhibition

por Gavagan, Maire, Jameson, Noel, Zalatan, Jesse G
Publicado 2023

CaMKII autophosphorylation can occur between holoenzymes without subunit exchange

por Lučić, Iva, Héluin, Léonie, Jiang, Pin-Lian, Castro Scalise, Alejandro G, Wang, Cong, Franz, Andreas, Heyd, Florian, Wahl, Markus C, Liu, Fan, Plested, Andrew JR
Publicado 2023

DnaJC7 specifically regulates tau seeding

por Perez, Valerie Ann, Sanders, David W, Mendoza-Oliva, Ayde, Stopschinski, Barbara Elena, Mullapudi, Vishruth, White, Charles L, Joachimiak, Lukasz A, Diamond, Marc I
Publicado 2023

Structural characterization of human RPA70N association with DNA damage response proteins

por Wu, Yeyao, Fu, Wangmi, Zang, Ning, Zhou, Chun
Publicado 2023

Divergent regulation of KCNQ1/E1 by targeted recruitment of protein kinase A to distinct sites on the channel complex

por Zou, Xinle, Shanmugam, Sri Karthika, Kanner, Scott A, Sampson, Kevin J, Kass, Robert S, Colecraft, Henry M
Publicado 2023

Kallistatin Deficiency Induces the Oxidative Stress-Related Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells: A Novel Protagonist in Age-Related Macular Degene...

por Shen, Gang, Li, Yanmei, Zeng, Yongcheng, Hong, Fuyan, Zhang, Jing, Wang, Yan, Zhang, Chengwei, Xiang, Wei, Wang, Jinhong, Fang, Zhenzhen, Qi, Weiwei, Yang, Xia, Gao, Guoquan, Zhou, Ti
Publicado 2023

A generic binding pocket for small molecule I(Ks) activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes

por Chan, Magnus, Sahakyan, Harutyun, Eldstrom, Jodene, Sastre, Daniel, Wang, Yundi, Dou, Ying, Pourrier, Marc, Vardanyan, Vitya, Fedida, David
Publicado 2023

Inositol pyrophosphate dynamics reveals control of the yeast phosphate starvation program through 1,5-IP(8) and the SPX domain of Pho81

por Chabert, Valentin, Kim, Geun-Don, Qiu, Danye, Liu, Guizhen, Michaillat Mayer, Lydie, Jamsheer K, Muhammed, Jessen, Henning J, Mayer, Andreas
Publicado 2023

FOXP2 confers oncogenic effects in prostate cancer

por Zhu, Xiaoquan, Chen, Chao, Wei, Dong, Xu, Yong, Liang, Siying, Jia, Wenlong, Li, Jian, Qu, Yanchun, Zhai, Jianpo, Zhang, Yaoguang, Wu, Pengjie, Hao, Qiang, Zhang, Linlin, Zhang, Wei, Yang, Xinyu, Pan, Lin, Qi, Ruomei, Li, Yao, Wang, Feiliang, Yi, Rui, Yang, Ze, Wang, Jianye, Zhao, Yanyang
Publicado 2023

A tRNA modification in Mycobacterium tuberculosis facilitates optimal intracellular growth

por Tomasi, Francesca G, Kimura, Satoshi, Rubin, Eric J, Waldor, Matthew K
Publicado 2023

The FAM104 proteins VCF1/2 promote the nuclear localization of p97/VCP

por Körner, Maria, Meyer, Susanne R, Marincola, Gabriella, Kern, Maximilian J, Grimm, Clemens, Schuelein-Voelk, Christina, Fischer, Utz, Hofmann, Kay, Buchberger, Alexander
Publicado 2023

Genetically engineered mesenchymal stem cells as a nitric oxide reservoir for acute kidney injury therapy

por Huang, Haoyan, Qian, Meng, Liu, Yue, Chen, Shang, Li, Huifang, Han, Zhibo, Han, Zhong-Chao, Chen, Xiang-Mei, Zhao, Qiang, Li, Zongjin
Publicado 2023

Dissecting the phase separation and oligomerization activities of the carboxysome positioning protein McdB

por Basalla, Joseph L, Mak, Claudia A, Byrne, Jordan A, Ghalmi, Maria, Hoang, Y, Vecchiarelli, Anthony G
Publicado 2023

Status and physiological significance of circulating adiponectin in the very old and centenarians: an observational study

por Sasaki, Takashi, Nishimoto, Yoshinori, Hirata, Takumi, Abe, Yukiko, Hirose, Nobuyoshi, Takayama, Michiyo, Takebayashi, Toru, Okano, Hideyuki, Arai, Yasumichi
Publicado 2023

Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses

por Kahraman, Sevim, Shibue, Kimitaka, De Jesus, Dario F, Kim, Hyunki, Hu, Jiang, Manna, Debasish, Wagner, Bridget, Choudhary, Amit, Kulkarni, Rohit N
Publicado 2023

GDF15 is required for cold-induced thermogenesis and contributes to improved systemic metabolic health following loss of OPA1 in brown adipocytes

por Jena, Jayashree, García-Peña, Luis Miguel, Weatherford, Eric T, Marti, Alex, Bjorkman, Sarah H, Kato, Kevin, Koneru, Jivan, Chen, Jason H, Seeley, Randy J, Abel, E Dale, Pereira, Renata O
Publicado 2023

Structural rather than catalytic role for mitochondrial respiratory chain supercomplexes

por Brischigliaro, Michele, Cabrera-Orefice, Alfredo, Arnold, Susanne, Viscomi, Carlo, Zeviani, Massimo, Fernández-Vizarra, Erika
Publicado 2023

Investigation of Inter- and Intra-Day Variability of Tear Fluid Regarding Flow Rate, Protein Concentration as well as Protein Composition

por Guntermann, Annika, Fatoba, Oluwaseun, Kronenberg, Marc, Reinehr, Sabrina, Grotegut, Pia, Schargus, Marc, Tsai, Teresa, Ivanova, Svetlana, Serschnitzki, Bettina, Kumowski, Nina, Maier, Christoph, Marcus, Katrin, Dick, H. Burkhard, Joachim, Stephanie C., May, Caroline
Publicado 2023

An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor

por Aguirre, Tim, Dornan, Gillian L, Hostachy, Sarah, Neuenschwander, Martin, Seyffarth, Carola, Haucke, Volker, Schütz, Anja, von Kries, Jens Peter, Fiedler, Dorothea
Publicado 2023

Proteostasis is differentially modulated by inhibition of translation initiation or elongation

por Clay, Khalyd J, Yang, Yongzhi, Clark, Christina, Petrascheck, Michael
Publicado 2023