A reverse transcriptase ribozyme

por Samanta, Biswajit, Joyce, Gerald F
Publicado 2017

AMPylation targets the rate-limiting step of BiP’s ATPase cycle for its functional inactivation

por Preissler, Steffen, Rohland, Lukas, Yan, Yahui, Chen, Ruming, Read, Randy J, Ron, David
Publicado 2017

Structural insight into TPX2-stimulated microtubule assembly

por Zhang, Rui, Roostalu, Johanna, Surrey, Thomas, Nogales, Eva
Publicado 2017

Structure of PINK1 and mechanisms of Parkinson's disease-associated mutations

por Kumar, Atul, Tamjar, Jevgenia, Waddell, Andrew D, Woodroof, Helen I, Raimi, Olawale G, Shaw, Andrew M, Peggie, Mark, Muqit, Miratul MK, van Aalten, Daan MF
Publicado 2017

Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID

por Gupta, Kapil, Watson, Aleksandra A, Baptista, Tiago, Scheer, Elisabeth, Chambers, Anna L, Koehler, Christine, Zou, Juan, Obong-Ebong, Ima, Kandiah, Eaazhisai, Temblador, Arturo, Round, Adam, Forest, Eric, Man, Petr, Bieniossek, Christoph, Laue, Ernest D, Lemke, Edward A, Rappsilber, Juri, Robinson, Carol V, Devys, Didier, Tora, Làszlò, Berger, Imre
Publicado 2017

Cryo-EM structure of a late pre-40S ribosomal subunit from Saccharomyces cerevisiae

por Heuer, André, Thomson, Emma, Schmidt, Christian, Berninghausen, Otto, Becker, Thomas, Hurt, Ed, Beckmann, Roland
Publicado 2017

Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis

por Steger, Martin, Diez, Federico, Dhekne, Herschel S, Lis, Pawel, Nirujogi, Raja S, Karayel, Ozge, Tonelli, Francesca, Martinez, Terina N, Lorentzen, Esben, Pfeffer, Suzanne R, Alessi, Dario R, Mann, Matthias
Publicado 2017

An unfolded protein-induced conformational switch activates mammalian IRE1

por Karagöz, G Elif, Acosta-Alvear, Diego, Nguyen, Hieu T, Lee, Crystal P, Chu, Feixia, Walter, Peter
Publicado 2017

Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control

por Carroni, Marta, Franke, Kamila B, Maurer, Michael, Jäger, Jasmin, Hantke, Ingo, Gloge, Felix, Linder, Daniela, Gremer, Sebastian, Turgay, Kürşad, Bukau, Bernd, Mogk, Axel
Publicado 2017

A recombinant BBSome core complex and how it interacts with ciliary cargo

por Klink, Björn Udo, Zent, Eldar, Juneja, Puneet, Kuhlee, Anne, Raunser, Stefan, Wittinghofer, Alfred
Publicado 2017

Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals

por Kühl, Inge, Miranda, Maria, Atanassov, Ilian, Kuznetsova, Irina, Hinze, Yvonne, Mourier, Arnaud, Filipovska, Aleksandra, Larsson, Nils-Göran
Publicado 2017

Deep transcriptome annotation enables the discovery and functional characterization of cryptic small proteins

por Samandi, Sondos, Roy, Annie V, Delcourt, Vivian, Lucier, Jean-François, Gagnon, Jules, Beaudoin, Maxime C, Vanderperre, Benoît, Breton, Marc-André, Motard, Julie, Jacques, Jean-François, Brunelle, Mylène, Gagnon-Arsenault, Isabelle, Fournier, Isabelle, Ouangraoua, Aida, Hunting, Darel J, Cohen, Alan A, Landry, Christian R, Scott, Michelle S, Roucou, Xavier
Publicado 2017

Immunoproteasome functions explained by divergence in cleavage specificity and regulation

por Winter, Michael B, La Greca, Florencia, Arastu-Kapur, Shirin, Caiazza, Francesco, Cimermancic, Peter, Buchholz, Tonia J, Anderl, Janet L, Ravalin, Matthew, Bohn, Markus F, Sali, Andrej, O'Donoghue, Anthony J, Craik, Charles S
Publicado 2017

Stabilization and structural analysis of a membrane-associated hIAPP aggregation intermediate

por Rodriguez Camargo, Diana C, Korshavn, Kyle J, Jussupow, Alexander, Raltchev, Kolio, Goricanec, David, Fleisch, Markus, Sarkar, Riddhiman, Xue, Kai, Aichler, Michaela, Mettenleiter, Gabriele, Walch, Axel Karl, Camilloni, Carlo, Hagn, Franz, Reif, Bernd, Ramamoorthy, Ayyalusamy
Publicado 2017

Conserved RNA-binding specificity of polycomb repressive complex 2 is achieved by dispersed amino acid patches in EZH2

por Long, Yicheng, Bolanos, Ben, Gong, Lihu, Liu, Wei, Goodrich, Karen J, Yang, Xin, Chen, Siming, Gooding, Anne R, Maegley, Karen A, Gajiwala, Ketan S, Brooun, Alexei, Cech, Thomas R, Liu, Xin
Publicado 2017

The gating cycle of a K(+) channel at atomic resolution

por Cuello, Luis G, Cortes, D Marien, Perozo, Eduardo
Publicado 2017

AAV-CRISPR/Cas9–Mediated Depletion of VEGFR2 Blocks Angiogenesis In Vitro

por Wu, Wenyi, Duan, Yajian, Ma, Gaoen, Zhou, Guohong, Park-Windhol, Cindy, D'Amore, Patricia A., Lei, Hetian
Publicado 2017

The AAA ATPase Vps4 binds ESCRT-III substrates through a repeating array of dipeptide-binding pockets

por Han, Han, Monroe, Nicole, Sundquist, Wesley I, Shen, Peter S, Hill, Christopher P
Publicado 2017

Yeast eIF4A enhances recruitment of mRNAs regardless of their structural complexity

por Yourik, Paul, Aitken, Colin Echeverría, Zhou, Fujun, Gupta, Neha, Hinnebusch, Alan G, Lorsch, Jon R
Publicado 2017

Ribosome surface properties may impose limits on the nature of the cytoplasmic proteome

por Schavemaker, Paul E, Śmigiel, Wojciech M, Poolman, Bert
Publicado 2017