Inter-membrane association of the Sec and BAM translocons for bacterial outer-membrane biogenesis

por Alvira, Sara, Watkins, Daniel W, Troman, Lucy, Allen, William J, Lorriman, James S, Degliesposti, Gianluca, Cohen, Eli J, Beeby, Morgan, Daum, Bertram, Gold, Vicki AM, Skehel, J Mark, Collinson, Ian
Publicado 2020

ClpAP proteolysis does not require rotation of the ClpA unfoldase relative to ClpP

por Kim, Sora, Zuromski, Kristin L, Bell, Tristan A, Sauer, Robert T, Baker, Tania A
Publicado 2020

Structural and functional characterization of G protein–coupled receptors with deep mutational scanning

por Jones, Eric M, Lubock, Nathan B, Venkatakrishnan, AJ, Wang, Jeffrey, Tseng, Alex M, Paggi, Joseph M, Latorraca, Naomi R, Cancilla, Daniel, Satyadi, Megan, Davis, Jessica E, Babu, M Madan, Dror, Ron O, Kosuri, Sriram
Publicado 2020

Synergy between Wsp1 and Dip1 may initiate assembly of endocytic actin networks

por Balzer, Connor J, James, Michael L, Narvaez-Ortiz, Heidy Y, Helgeson, Luke A, Sirotkin, Vladimir, Nolen, Brad J
Publicado 2020

Increasing the uptake of carbon dioxide

por Franklin, Eric, Jonikas, Martin
Publicado 2020

Functional reconstitution of a bacterial CO(2) concentrating mechanism in Escherichia coli

por Flamholz, Avi I, Dugan, Eli, Blikstad, Cecilia, Gleizer, Shmuel, Ben-Nissan, Roee, Amram, Shira, Antonovsky, Niv, Ravishankar, Sumedha, Noor, Elad, Bar-Even, Arren, Milo, Ron, Savage, David F
Publicado 2020

Rationally derived inhibitors of hepatitis C virus (HCV) p7 channel activity reveal prospect for bimodal antiviral therapy

por Shaw, Joseph, Gosain, Rajendra, Kalita, Monoj Mon, Foster, Toshana L, Kankanala, Jayakanth, Mahato, D Ram, Abas, Sonia, King, Barnabas J, Scott, Claire, Brown, Emma, Bentham, Matthew J, Wetherill, Laura, Bloy, Abigail, Samson, Adel, Harris, Mark, Mankouri, Jamel, Rowlands, David J, Macdonald, Andrew, Tarr, Alexander W, Fischer, Wolfgang B, Foster, Richard, Griffin, Stephen
Publicado 2020

Altered Protein Function Caused by AMD-associated Variant rs704 Links Vitronectin to Disease Pathology

por Biasella, Fabiola, Plössl, Karolina, Karl, Claudia, Weber, Bernhard H. F., Friedrich, Ulrike
Publicado 2020

FLEXIQuant-LF to quantify protein modification extent in label-free proteomics data

por Schlaffner, Christoph N, Kahnert, Konstantin, Muntel, Jan, Chauhan, Ruchi, Renard, Bernhard Y, Steen, Judith A, Steen, Hanno
Publicado 2020

Cryo-EM structure of the calcium release-activated calcium channel Orai in an open conformation

por Hou, Xiaowei, Outhwaite, Ian R, Pedi, Leanne, Long, Stephen Barstow
Publicado 2020

Cross-talk between individual phenol-soluble modulins in Staphylococcus aureus biofilm enables rapid and efficient amyloid formation

por Zaman, Masihuz, Andreasen, Maria
Publicado 2020

The energy savings-oxidative cost trade-off for migratory birds during endurance flight

por McWilliams, Scott, Pierce, Barbara, Wittenzellner, Andrea, Langlois, Lillie, Engel, Sophia, Speakman, John R, Fatica, Olivia, DeMoranville, Kristen, Goymann, Wolfgang, Trost, Lisa, Bryla, Amadeusz, Dzialo, Maciej, Sadowska, Edyta, Bauchinger, Ulf
Publicado 2020

Spreading of a mycobacterial cell-surface lipid into host epithelial membranes promotes infectivity

por Cambier, CJ, Banik, Steven M, Buonomo, Joseph A, Bertozzi, Carolyn R
Publicado 2020

Intracellular complexities of acquiring a new enzymatic function revealed by mass-randomisation of active-site residues

por Hall, Kelsi R, Robins, Katherine J, Williams, Elsie M, Rich, Michelle H, Calcott, Mark J, Copp, Janine N, Little, Rory F, Schwörer, Ralf, Evans, Gary B, Patrick, Wayne M, Ackerley, David F
Publicado 2020

In vitro reconstitution of dynamically interacting integral membrane subunits of energy-coupling factor transporters

por Setyawati, Inda, Stanek, Weronika K, Majsnerowska, Maria, Swier, Lotteke J Y M, Pardon, Els, Steyaert, Jan, Guskov, Albert, Slotboom, Dirk J
Publicado 2020

Biophysical characterization of antibacterial compounds derived from pathogenic fungi Ganoderma boninense

por Abdullah, Syahriel, Oh, Yoon Sin, Kwak, Min-Kyu, Chong, KhimPhin
Publicado 2020

Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes

por Preissler, Steffen, Rato, Claudia, Yan, Yahui, Perera, Luke A, Czako, Aron, Ron, David
Publicado 2020

Transport mechanism of P4 ATPase phosphatidylcholine flippases

por Bai, Lin, You, Qinglong, Jain, Bhawik K, Duan, H Diessel, Kovach, Amanda, Graham, Todd R, Li, Huilin
Publicado 2020

Mechanistic insights into volatile anesthetic modulation of K2P channels

por Wague, Aboubacar, Joseph, Thomas T, Woll, Kellie A, Bu, Weiming, Vaidya, Kiran A, Bhanu, Natarajan V, Garcia, Benjamin A, Nimigean, Crina M, Eckenhoff, Roderic G, Riegelhaupt, Paul M
Publicado 2020

A structure of substrate-bound Synaptojanin1 provides new insights in its mechanism and the effect of disease mutations

por Paesmans, Jone, Martin, Ella, Deckers, Babette, Berghmans, Marjolijn, Sethi, Ritika, Loeys, Yannick, Pardon, Els, Steyaert, Jan, Verstreken, Patrik, Galicia, Christian, Versées, Wim
Publicado 2020