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30021por Almeida, Eduardo L., Carrillo Rincón, Andrés Felipe, Jackson, Stephen A., Dobson, Alan D. W.“…In order to further investigate this class of PETase-like enzymes, we employed an in silico-based screening approach on the biotechnologically relevant genus Streptomyces, including terrestrial and marine isolates; in a search for potential PETase homologs. …”
Publicado 2019
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30022por Ye, Sunghyeok, Kwon, Woo‐Keun, Bae, Taegeun, Kim, Sunghyun, Lee, Jang‐Bo, Cho, Tai‐Hyoung, Park, Jung‐Yul, Kim, Kyoungmi, Hur, Junho K., Hur, Junseok W.“…First, we created TGF‐β receptor 1 (TGFBR1) knock out (KO) cells with CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 biotechnology and treated them with TGF‐β1 to determine the effects of blocking the TGF‐β pathway. …”
Publicado 2019
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30023“…We expect this advance to accelerate biotechnology-oriented engineering processes in fungi.…”
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30024por Cox, Deborah Elizabeth, Dyer, Steven, Weir, Ryan, Cheseto, Xavier, Sturrock, Matthew, Coyne, Danny, Torto, Baldwyn, Maule, Aaron G., Dalzell, Johnathan J.“…ABC-C6 represents a promising target for breeding or biotechnology intervention strategies as gene knockdown leads to the repulsion of economically important plant parasites and retains attraction of the beneficial rhizobacterium B. subtilis. …”
Publicado 2019
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30025por Ugur, Muhammet Rasit, Dinh, Thu, Hitit, Mustafa, Kaya, Abdullah, Topper, Einko, Didion, Bradley, Memili, Erdogan“…Although univariate analysis did not yield significant differences in amino acid concentration between the two groups, these findings are significant that they indicate the potentially important roles of amino acids in seminal plasma, thereby building a foundation for the fundamental science of cryobiology and reproductive biotechnology.…”
Publicado 2020
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30026“…Forty bacterial whole-genome sequences of STEC strains obtained from National Center for Biotechnology Information (NCBI) were used for the prophage prediction using PHASTER webserver. …”
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30027por Fejes, Balázs, Ouedraogo, Jean-Paul, Fekete, Erzsébet, Sándor, Erzsébet, Flipphi, Michel, Soós, Áron, Molnár, Ákos P., Kovács, Béla, Kubicek, Christian P., Tsang, Adrian, Karaffa, Levente“…BACKGROUND: Citric acid, a commodity product of industrial biotechnology, is produced by fermentation of the filamentous fungus Aspergillus niger. …”
Publicado 2020
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30028por Van Liedekerke, Paul, Neitsch, Johannes, Johann, Tim, Warmt, Enrico, Gonzàlez-Valverde, Ismael, Hoehme, Stefan, Grosser, Steffen, Kaes, Josef, Drasdo, Dirk“…Mathematical models are increasingly designed to guide experiments in biology, biotechnology, as well as to assist in medical decision making. …”
Publicado 2019
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30029por Li, Li, Shuai, Liang, Sun, Jian, Li, Changbao, Yi, Ping, Zhou, Zhugui, He, Xuemei, Ling, Dongning, Sheng, Jinfeng, Kong, Kin‐Weng, Zheng, Fengjin, Li, Jiemin, Liu, Guoming, Xin, Ming, Li, Zhichun, Tang, Yayuan“…The two homologous ethylene receptor genes, ETR1 and ERS1 (i.e., MiETR1 and MiERS1), were obtained and deposited in GenBank(®) (National Center for Biotechnology Information‐National Institutes of Health [NCBI‐NIH]) (KY002681 and KY002682). …”
Publicado 2020
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30030por Yang, Xulei, Wu, Yuanyuan, Zhang, Yu, Yang, En, Qu, Yuan, Xu, Huini, Chen, Yuhui, Irbis, Chagan, Yan, Jinping“…In conclusion, it is the first time to report a thermo-activation laccase from a thermophilic T. trogii strain, which has a better enzyme property and higher decolorization ability among fungal laccases, and it also has a further application prospective in the field of biotechnology.…”
Publicado 2020
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30031“…The Technology Innovation Maturation Evaluation (TIME) model was previously introduced to study the life-cycles of biotechnologies. METHODS: PubMed database was searched 1900–2015 to review relevant publications. …”
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30032por Pammolli, Fabio, Righetto, Lorenzo, Abrignani, Sergio, Pani, Luca, Pelicci, Pier Giuseppe, Rabosio, Emanuele“…Moreover, we show that biotechnology companies have reached levels of productivity in project development that are equivalent to those of large pharmaceutical companies. …”
Publicado 2020
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30033por Sanjeeva Rao, D., Neeraja, C. N., Madhu Babu, P., Nirmala, B., Suman, K., Rao, L. V. Subba, Surekha, K., Raghu, P., Longvah, T., Surendra, P., Kumar, Rajesh, Babu, V. Ravindra, Voleti, S. R.“…With the existing significant genetic variability for high zinc in polished rice, the development of biofortified rice varieties was targeted in India with support from HarvestPlus, Department of Biotechnology, and Indian Council of Agricultural Research of Government of India. …”
Publicado 2020
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30034por Medeiros de Azevedo, Wendell, Ferreira Ribeiro de Oliveira, Larissa, Alves Alcântara, Maristela, Tribuzy de Magalhães Cordeiro, Angela Maria, Florentino da Silva Chaves Damasceno, Karla Suzanne, Kelly de Araújo, Nathália, Fernandes de Assis, Cristiane, de Sousa Junior, Francisco Caninde“…Moreover, cacay oil presents as an alternative source of raw materials for cosmetic and biotechnology industries due to its high concentration of PUFA and for being a rich source of phenolic compounds.…”
Publicado 2020
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30035“…The National Center for Biotechnology Information database revealed that LRP6 was relatively highly expressed in placental tissues, but was poorly expressed in PE tissues and trophoblast cell lines. …”
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30036por Yang, Jordan, Naik, Nandita, Patel, Jagdish Suresh, Wylie, Christopher S., Gu, Wenze, Huang, Jessie, Ytreberg, F. Marty, Naik, Mandar T., Weinreich, Daniel M., Rubenstein, Brenda M.“…With such predictive abilities in hand, researchers would be able to more accurately forecast how organisms will evolve and how proteins with novel functions could be engineered, leading to revolutionary advances in medicine and biotechnology. In this work, we assemble the largest reported set of experimental TEM-1 β-lactamase folding free energies and use this data in conjunction with previously acquired fitness data and computational free energy predictions to determine how much of the fitness of β-lactamase can be directly predicted by thermodynamic folding and binding free energies. …”
Publicado 2020
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30037por Ding, Junmei, Zhou, Yang, Wang, Chaofan, Peng, Zheng, Mu, Yuelin, Tang, Xianghua, Huang, Zunxi“…Cell surface display of recombinant proteins has become a powerful tool for biotechnology applications. In this current study, a carboxylesterase was displayed on the surface of Escherichia coli cells, for use as whole-cell biocatalyst in diisobutyl phthalate biodegradation. …”
Publicado 2020
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30038por Benavides, Fernando, Sutovsky, Peter, López, Verónica, Kennedy, Chelsey, Echevarría, Luisa“…However, there are few advances in reproductive biotechnology. Thus, there is a lack of information about harmless, efficient semen collection techniques in the species. …”
Publicado 2020
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30039por Kyaw, Yi Yi, Lwin, Aye Aye, Aye, Khin Saw, Thu, Hlaing Myat, Htun, Moh Moh, Soe, Hnin Ohmar, Aye, Kay Thi, Thant, Kyaw Zin, Hwang, Hyeon Jeong, Cheong, JaeHun“…The resulting sequences were then edited, aligned, and compared with reference sequences using the National Centre for Biotechnology Information (NCBI) web-based genotyping tool. …”
Publicado 2020
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30040por Rodrigues, Grazielle Lima, Panzenhagen, Pedro, Ferrari, Rafaela Gomes, dos Santos, Anamaria, Paschoalin, Vania Margaret Flosi, Conte-Junior, Carlos Adam“…A total of 930 whole-genome sequences of Salmonella were retrieved from the public database of the National Biotechnology Information Center (NCBI). A total of 65 distinct resistance genes were detected, and the most frequent ones were tet(A), sul2, and fosA7. …”
Publicado 2020
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