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  1. 30181
    “…Six series of microarray data from a public transcriptome database, the Gene Expression Omnibus of the National Center for Biotechnology Information, are related to anther and pollen development. …”
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    Genome-wide analyses of late pollen-preferred genes conserved in various rice cultivars and functional identification of a gene involved in the key processes of late pollen development
  2. 30182
    “…CONCLUSION: By abolishing its natural catabolic network for aromatic compounds, C. glutamicum was turned into a versatile microbial platform for aromatics production, which could be exemplarily demonstrated by rapidly engineering this platform organism towards producing four biotechnologically interesting hydroxybenzoates. Production of these compounds was optimized following different metabolic engineering strategies leading to increased precursor availability. …”
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    Corynebacterium glutamicum as platform for the production of hydroxybenzoic acids
  3. 30183
    “…METHODS: The study was approved by the Ethics Committee of the National Center for Biotechnology. Venous blood samples from 369 healthy Kazakh blood donors, whose blood types had been determined by serological methods, were collected after obtaining informed consent. …”
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    ABO Blood Group Genotyping by Real-time PCR in Kazakh Population
  4. 30184
    “…This parameter has important implications in biotechnology and wastewater treatment, where low growth yields are often preferred to minimize the production of microbial biomass. …”
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    Shewanella oneidensis MR-1 Utilizes both Sodium- and Proton-Pumping NADH Dehydrogenases during Aerobic Growth
  5. 30185
    “…Cytokine expression was evaluated by immunostaining in 96 biopsies (48 paired reaction-free/reactional lesions, 24 T1R, 24 T2R) using rabbit polyclonal anti human TGF-β1, IFN-γ, IL-17 antibodies (Santa Cruz Biotechnology CA, USA). T(reg) cell counts in leprosy reactional lesions were higher compared to reaction-free (p = 0.002). …”
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    In situ T regulatory cells and Th17 cytokines in paired samples of leprosy type 1 and type 2 reactions
  6. 30186
    “…IMPORTANCE The genus Lactobacillus contains more than 200 species, many of which are exploited in the food and biotechnology industries and in medicine. Prediction of intrinsic vancomycin resistance has thus far been limited to selected Lactobacillus species. …”
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    d-Alanyl-d-Alanine Ligase as a Broad-Host-Range Counterselection Marker in Vancomycin-Resistant Lactic Acid Bacteria
  7. 30187
    “…This feature has been exploited in biotechnology to establish platform strains with high secretory capacity including Aspergillus niger. …”
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    Construction of an improved Aspergillus niger platform for enhanced glucoamylase secretion
  8. 30188
    “…BACKGROUND: Models of metabolism are often used in biotechnology and pharmaceutical research to identify drug targets or increase the direct production of valuable compounds. …”
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    DMPy: a Python package for automated mathematical model construction of large-scale metabolic systems
  9. 30189
    “…For integrated analysis, a total of 5 gene expression profiling datasets for 3 different stages of breast cancer (stages I–III) were downloaded from the Gene Expression Omnibus of the National Center for Biotechnology Information. Pre-processing of these datasets was performed using the Robust Multi-array Average algorithm and global renormalization was performed for all studies. …”
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    Comprehensive integrated analysis of gene expression datasets identifies key anti-cancer targets in different stages of breast cancer
  10. 30190
    “…The conversion of repressor proteins to potential activators in other biotechnologically used filamentous fungi can be applied to increase their enzyme production capacities. …”
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    Truncation of the transcriptional repressor protein Cre1 in Trichoderma reesei Rut-C30 turns it into an activator
  11. 30191
    “…CONCLUSIONS: As compared to traditional silicone filled full-mass implants, breast augmentations with B-Lite lightweight breast implants (G&G Biotechnology Ltd., Haifa, Israel) elicit less posttreatment pain and require less down-time, ultimately, meeting patients’ quest for desired breast shape at minimal discomfort. …”
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    Reduced Pain and Accelerated Recovery Following Primary Breast Augmentation With Lightweight Breast Implants
  12. 30192
    “…Our results show that the ANCHOR technology provides an efficient tool for the study of complex DNA viruses and a new, highly promising system for the development of innovative biotechnology applications. IMPORTANCE The ANCHOR technology is currently the most powerful tool to follow and quantify the replication of HCMV in living cells and to gain new insights into its biology. …”
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    Real-Time Visualization and Quantification of Human Cytomegalovirus Replication in Living Cells Using the ANCHOR DNA Labeling Technology
  13. 30193
    “…DATA AVAILABILITY: DNA methylation and gene expression datasets generated and analysed during the current study are available at the National Center for Biotechnology Information (NCBI) Gene Expression Omnibus (GEO) database (http://www.ncbi.nlm.nih.gov/geo) under accession numbers GSE106099 and GSE103552, respectively. …”
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    Human fetoplacental arterial and venous endothelial cells are differentially programmed by gestational diabetes mellitus, resulting in cell-specific barrier function changes
  14. 30194
    “…DATA AVAILABILITY: Gene expression data files are publicly available through the National Center for Biotechnology Information Gene Expression Omnibus (accession number GSE102234). …”
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    Innate immune activity as a predictor of persistent insulin secretion and association with responsiveness to CTLA4-Ig treatment in recent-onset type 1 diabetes
  15. 30195
    “…Differential expression between atherosclerotic group and non-atherosclerotic group samples was analyzed using the Gene-Cloud of Biotechnology Information platform. Targetscan and miRanda were then used to predict targets of DE-miRs. …”
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    MicroRNA profiling of diabetic atherosclerosis in a rat model
  16. 30196
    “…The elimination of omega-5 gliadins from wheat flour through biotechnology or breeding approaches could reduce the immunogenic potential and adverse health effects of the flour. …”
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    Towards reducing the immunogenic potential of wheat flour: omega gliadins encoded by the D genome of hexaploid wheat may also harbor epitopes for the serious food allergy WDEIA
  17. 30197
    “…Halophilic bacteria constitute an untapped natural resource for biotechnology in the Philippines. The present study demonstrated their potential use in bioremediation of recalcitrant hydrocarbons in the environment. …”
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    Degradation of Polycyclic Aromatic Hydrocarbons by Moderately Halophilic Bacteria from Luzon Salt Beds
  18. 30198
    “…Among the many virus defense mechanisms, RNA interference is shown to be the most promising transgenic disease-control strategy in plant biotechnology. The present study describes the production of transgenic PPV resistant European plum “Startovaya” (P. domestica L.) through the Agrobacterium-mediated transformation of in vitro leaf explants. …”
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    Agrobacterium-Mediated Transformation of Russian Commercial Plum cv. “Startovaya” (Prunus domestica L.) With Virus-Derived Hairpin RNA Construct Confers Durable Resistance to PPV Infection in Mature Plants
  19. 30199
    “…BACKGROUND: Biological routes for utilizing both carbohydrates and lignin are important to reach the ultimate goal of bioconversion of full carbon in biomass into biofuels and biochemicals. Recent biotechnology advances have shown promises toward facilitating biological transformation of lignin into lipids. …”
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    Discovery of potential pathways for biological conversion of poplar wood into lipids by co-fermentation of Rhodococci strains
  20. 30200
    “…DNA was extracted from blood and hair samples, quantified and prepared at 50 ng/μl concentration for sequencing at the Agricultural Research Council Biotechnology Platform using an Illumina HiSeq 2500. …”
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    Genome-Wide SNP Discovery in Indigenous Cattle Breeds of South Africa
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