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30201por Fornace, Kimberly M, Brock, Paddy M, Abidin, Tommy R, Grignard, Lynn, Herman, Lou S, Chua, Tock H, Daim, Sylvia, William, Timothy, Patterson, Catriona L E B, Hall, Tom, Grigg, Matthew J, Anstey, Nicholas M, Tetteh, Kevin K A, Cox, Jonathan, Drakeley, Chris J“…FUNDING: UK Medical Research Council, Natural Environment Research Council, Economic and Social Research Council, and Biotechnology and Biosciences Research Council.…”
Publicado 2019
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30202“…To talk about the success of artificial insemination of horses in Europe, it is necessary to look thoroughly at these aspects that affect the popularity of this reproduction biotechnology, and in particular to improve the quality of insemination doses. …”
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30203por Song, Sung Kyu, Jung, Woon Yong, Park, Seung-Keun, Chung, Chul-Woon, Park, Yongkeun“…MATERIALS AND METHODS: Eligible two datasets (accession number: GSE20594 and GSE67140) were collected from the National Center for Biotechnology Information’s (NCBI) Gene Expression Omnibus (GEO) database to compare miRNAs expression between HCC with and without gross VI. …”
Publicado 2019
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30204por Li, Fei, Jin, Yonghao, Liu, Weisong, Rawat, Bhanu Pratap Singh, Cai, Pengshan, Yu, Hong“…We then further fine-tuned EhrBERT, BioBERT, and BERT on three annotated corpora for biomedical and clinical entity normalization: the Medication, Indication, and Adverse Drug Events (MADE) 1.0 corpus, the National Center for Biotechnology Information (NCBI) disease corpus, and the Chemical-Disease Relations (CDR) corpus. …”
Publicado 2019
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30205por Ongey, Elvis L., Santolin, Lara, Waldburger, Saskia, Adrian, Lorenz, Riedel, Sebastian L., Neubauer, Peter“…In the current study we developed a scale-up strategy for the biotechnologically relevant heterologous production of RumA, aimed at overproducing the peptide under conditions comparable with those in industrial production settings. …”
Publicado 2019
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30206por Liu, Rong-Fei, He, Zhen-Jian, Mei, Peng, Xi, Jia-Cheng, Cao, Xu-Dong, Yuan, Li-Hong, Lu, Jia-Hai“…METHODS: ZIKV genomic sequences were retrieved from the National Center for Biotechnology Information database through stratified sampling. …”
Publicado 2019
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30207“…METHODS: HA and NA sequences of the seasonal isolates circulating from December 1, 2017 to February 28, 2018, and in the previously other 7 winters in northern hemisphere from Global Initiative on Sharing All Influenza Data (GISAID) and the influenza database of National Center for Biotechnology Information (NCBI). Phylogenetic trees and genetic distances were constructed or calculated by using MAFFT and MEGA 6.0 software. …”
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30208por Zong, Yuan, Li, Shiming, Xi, Xinyuan, Cao, Dong, Wang, Zhong, Wang, Ran, Liu, Baolong“…This research will give more information about the function of MYB transcription factors on the anthocyanin biosynthesis and other chemical compounds and be of benefit to obtaining new plant cultivars with high anthocyanin content by biotechnology.…”
Publicado 2019
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30209por Álvarez-Escribano, Isidro, Sasse, Christoph, Bok, Jin Woo, Na, Hyunsoo, Amirebrahimi, Mojgan, Lipzen, Anna, Schackwitz, Wendy, Martin, Joel, Barry, Kerrie, Gutiérrez, Gabriel, Cea-Sánchez, Sara, Marcos, Ana T., Grigoriev, Igor V., Keller, Nancy P., Braus, Gerhard H., Cánovas, David“…Deletion of the NHEJ machinery results in a slight increase in the mutation rate, but at a rate we suggest is still safe to use for biotechnology purposes. Unexpectedly, we found GC→TA transversions predominated only in the species A. flavus, which could be generated by the hepatocarcinogen secondary metabolite aflatoxin. …”
Publicado 2019
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30210por Garbuzenko, Olga B., Kuzmov, Andriy, Taratula, Oleh, Pine, Sharon R., Minko, Tamara“…In order to minimize and even overcome these limitations, we are proposing a novel multi-tier biotechnology treatment approach that includes: (1) suppression of all four types of EGFR-TKs by a pool of small interfering RNAs (siRNAs); (2) induction of cell death by an anticancer drug, (3) enhancing the efficiency of the treatment by the local inhalation delivery of therapeutic agents directly to the lungs (passive targeting), (4) active receptor-mediated targeting of the therapy specifically to cancer cells that in turn should minimize adverse side effects of treatment and (5) increasing the stability, solubility, and cellular penetration of siRNA and drug by using tumor targeted Nanostructured Lipid Carriers (NLC). …”
Publicado 2019
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30211“…Furthermore, non-coding RNA regulatory networks were constructed using the Gene-Cloud Biotechnology information website. A total of 359 common DEGs (155 upregulated and 204 downregulated) were identified, which were predominantly enriched in ‘mitotic nuclear division’, ‘cell division’, ‘cell cycle’ and ‘p53 signaling pathway’. …”
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30212por Duracka, Michal, Lukac, Norbert, Kacaniova, Miroslava, Kantor, Attila, Hleba, Lukas, Ondruska, Lubomir, Tvrda, Eva“…As such, we decided to compare the effects of selected natural biomolecules (resveratrol-RES, quercetin-QUE and curcumin-CUR) with routinely used antibiotics in animal biotechnologies (penicillin-PEN, gentamicin-GEN and kanamycin-KAN) on the rabbit sperm vitality in the presence of Enterococcus faecalis. …”
Publicado 2019
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30213por Wang, Fangce, Li, Zheng, Wang, Guangming, Tian, Xiaoxue, Zhou, Jie, Yu, Wenlei, Fan, Zhuoyi, Dong, Lin, Lu, Jinyuan, Xu, Jun, Zhang, Wenjun, Liang, Aibin“…The transcriptomic and epigenetic datasets were downloaded from National Center of Biotechnology Information Gene Expression Omnibus (GEO) database. …”
Publicado 2020
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30214por Hamzeh, Osama, Alkhateeb, Abedalrhman, Zheng, Julia Zhuoran, Kandalam, Srinath, Leung, Crystal, Atikukke, Govindaraja, Cavallo-Medved, Dora, Palanisamy, Nallasivam, Rueda, Luis“…We obtained a publicly-available RNA-Seq dataset of a cohort of 104 prostate cancer patients from the National Center for Biotechnology Information’s (NCBI) Gene Expression Omnibus (GEO) repository, and categorised patients based on their Gleason scores to create a hierarchy of disease progression. …”
Publicado 2019
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30215“…Recent advances, especially in the last 15 years in genomics, proteomics, biotechnology, immunology, pathogenesis, and vaccine formulation and delivery have dramatically changed our approach to vaccine development. …”
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30216por Nemr, Rahma A., Khalil, Mohab, Sarhan, Mohamed S., Abbas, Mohamed, Elsawey, Hend, Youssef, Hanan H., Hamza, Mervat A., Morsi, Ahmed T., El-Tahan, Mahmoud, Fayez, Mohamed, Patz, Sascha, Witzel, Katja, Ruppel, Silke, El-Sahhar, Kassem F., Hegazi, Nabil A.“…This is an effort to access novel isolates that are more adapted and competitive in their natural environments, especially those subjected to abiotic stresses like those prevailing in arid/semi-arid zones, and, consequently, to support the application of agro-biotechnologies, among other technologies, to improving agriculture in such zones.…”
Publicado 2020
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30217por Schäffer, Alejandro A., Hatcher, Eneida L., Yankie, Linda, Shonkwiler, Lara, Brister, J. Rodney, Karsch-Mizrachi, Ilene, Nawrocki, Eric P.“…The National Center for Biotechnology Information (NCBI) previously made available a tool for validating and annotating influenza virus sequences that is used to check submissions to GenBank. …”
Publicado 2020
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30218por Gonzalez-Serrano, Rafael, Dunne, Matthew, Rosselli, Riccardo, Martin-Cuadrado, Ana-Belen, Grosboillot, Virginie, Zinsli, Léa V., Roda-Garcia, Juan J., Loessner, Martin J., Rodriguez-Valera, Francisco“…Due to their genetic plasticity, studying RBPs and their associated chaperones can shed new light onto viral evolution affecting phage-host interactions, which is essential for fields such as phage therapy or biotechnology. In addition, since marine phages constitute one of the most important reservoirs of noncharacterized genetic diversity on the planet, their genomic and functional characterization may be of paramount importance for the discovery of novel genes with potential applications.…”
Publicado 2020
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30219“…PURPOSE: Selenium nanoparticles (SeNP) have several applications in the field of biotechnology, including their use as anti-cancer drugs. …”
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30220“…BACKGROUND: Identification of molecular characterization of genes underlying livestock productive traits may allow applying advanced biotechnology techniques to improve animal productivity. …”
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