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  1. 31461
    por Houdebine, Louis Marie
    Publicado 2000
    “…The production of recombinant proteins is one of the major successes of biotechnology. Animal cells are required to synthesize proteins with the appropriate post-translational modifications. …”
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    Transgenic animal bioreactors
  2. 31462
    “…SIMPLE SUMMARY: The knowledge of physiological events associated with canine reproduction involving oocyte developmental potential is essential to increase the success of reproductive biotechnologies in this species. In mammals, the oocytes are closely surrounded by a group of cells known as the cumulus cells. …”
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    GDF-9 and BMP-15 mRNA Levels in Canine Cumulus Cells Related to Cumulus Expansion and the Maturation Process
  3. 31463
    “…In this study, we performed bioinformatics analysis using data from the National Center for Biotechnology Information-Gene Expression Omnibus (NCBI-GEO) databases and verified the selected core genes in a mouse model of dextran sulfate sodium (DSS)-induced colitis. …”
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    Identification of differentially expressed genes in ulcerative colitis and verification in a colitis mouse model by bioinformatics analyses
  4. 31464
    “…ABSTRACT: This review article focuses on the current state-of-the-art cellular and molecular biotechnology for the over-production of clinically relevant therapeutic and anabolic growth factors. …”
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    Over-Production of Therapeutic Growth Factors for Articular Cartilage Regeneration by Protein Production Platforms and Protein Packaging Cell Lines
  5. 31465
    por Yong, Hannah E J, Chan, Shiao-Yng
    Publicado 2020
    “…SEARCH METHODS: The PubMed database, National Center for Biotechnology Information and European Bioinformatics Institute dataset repositories were searched, to identify all relevant human studies using ‘placenta’, ‘decidua’, ‘trophoblast’, ‘transcriptome’, ‘microarray’ and ‘RNA sequencing’ as search terms until May 2019. …”
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    Current approaches and developments in transcript profiling of the human placenta
  6. 31466
    “…The top 3 systems were generated by IBM Research, the National Center for Biotechnology Information, and the University of Florida, with Pearson correlations of r=.9010, r=.8967, and r=.8864, respectively. …”
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    The 2019 n2c2/OHNLP Track on Clinical Semantic Textual Similarity: Overview
  7. 31467
    “…DESIGN, SETTING, AND PARTICIPANTS: In this prognostic study, the National Center for Biotechnology Information Gene Expression Omnibus was used to search for microarray gene expression data from kidney transplant tissues, resulting in 38 studies from January 1, 2017, to December 31, 2018. …”
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    Molecular Diversity of Clinically Stable Human Kidney Allografts
  8. 31468
    “…Bulk production of medium-chain carboxylates (MCCs) with 6–12 carbon atoms is of great interest to biotechnology. Open cultures (e.g., reactor microbiomes) have been utilized to generate MCCs in bioreactors. …”
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    The Isolate Caproiciproducens sp. 7D4C2 Produces n-Caproate at Mildly Acidic Conditions From Hexoses: Genome and rBOX Comparison With Related Strains and Chain-Elongating Bacteria
  9. 31469
    “…BACKGROUND: Microalgae can contribute to more than 40% of global primary biomass production and are suitable candidates for various biotechnology applications such as food, feed products, drugs, fuels, and wastewater treatment. …”
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    Water reuse and growth inhibition mechanisms for cultivation of microalga Euglena gracilis
  10. 31470
    “…FUNDING: Wellcome Trust–Department of Biotechnology India Alliance.…”
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    Task-sharing interventions for improving control of diabetes in low-income and middle-income countries: a systematic review and meta-analysis
  11. 31471
    “…Overall, no severe or serious adverse events or discontinuations due to adverse events were observed within the dose range evaluated for VIR-2218 in healthy volunteers (Vir Biotechnology, Inc., unpublished data). CONCLUSIONS: VIR-2218 showed favorable pharmacokinetics in healthy volunteers supportive of subcutaneous dosing and continued development in patients with chronic HBV infection. …”
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    Clinical and Preclinical Single-Dose Pharmacokinetics of VIR-2218, an RNAi Therapeutic Targeting HBV Infection
  12. 31472
    “…In addition, nuclear expression assessed by the QS system using Abcam and Santa Cruz Biotechnology seems to be the most commonly used and reproducible IHC method for assessing PARP expression. …”
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    High Poly(ADP-Ribose) Polymerase Expression Does Relate to Poor Survival in Solid Cancers: A Systematic Review and Meta-Analysis
  13. 31473
    “…DISCLOSURES: Akiko Iwasaki, PhD, 4Bio (Consultant, Advisor or Review Panel member)Adaptive Biotechnologies (Consultant, Advisor or Review Panel member)Blavatnik (Grant/Research Support)HHMI (Grant/Research Support)Mathers (Grant/Research Support)NIH (Grant/Research Support)Spring Discovery (Grant/Research Support)Spring Discovery (Consultant, Advisor or Review Panel member)Vedanta InProTher (Consultant, Advisor or Review Panel member)Yale School of Medicine (Grant/Research Support) Nathan D. …”
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    301. Detection of Pneumococcal Pneumonia During SARS-CoV-2 Infection
  14. 31474
    “…DISCLOSURES: Mary Beth Wire, Pharm#, Lysovant (Consultant) Soo youn Jun, PhD, iNtRON Biotechnology (Consultant) In-Jin Jany, PhD, iNtRON (Consultant) Jun Gi Hwang, PhD, Lysovant (Consultant) David Huang, MD, PhD, Lysovant (Consultant)…”
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    1099. Evaluation of the Safety and Pharmacokinetics (PK) following Administration of Single and Multiple Doses of Anti-Staphylococcal Lysin, LSVT-1701, in Healthy Adult Subjects
  15. 31475
    “…MATERIALS AND METHODS: The amino acid sequences of the structural proteins were retrieved from the National Center for Biotechnology Information protein database. The sequences were evaluated in CD-HIT Suite wherein resulting representative sequences were aligned in Clustal Omega. …”
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    In silico analysis of highly conserved cytotoxic T-cell epitopes in the structural proteins of African swine fever virus
  16. 31476
    “…Lignin peroxidase is a heme-containing biocatalyst, well-known for its diverse applications in the fields from environmental chemistry to biotechnology. LiP-mediated oxidative catalysis is H(2)O(2)-dependent, and can oxidize phenolic, and non-phenolic substrates by oxidative cleavage of the C–C and C–O bonds of lignin. …”
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    In silico exploration of lignin peroxidase for unraveling the degradation mechanism employing lignin model compounds
  17. 31477
    “…This study reports an artificial diet-based multi-well plate method and the first findings on the potential application of biotechnology in the control of the banana weevil using dietary RNAi, which would arguably provide the most sustainable and practical method for dsRNA delivery. …”
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    First Evidence of Feeding-Induced RNAi in Banana Weevil via Exogenous Application of dsRNA
  18. 31478
    “…Based on 16S rRNA gene sequence analysis, the strain was identified as Bacillus sp. and submitted to the NCBI database, Sector of Applied Bio-catalysis, University Institute of Biotechnology, Vilnius, Lithuania and allocated the accession number KY882273. …”
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    Phosphate Solubilizing Microorganism Bacillus sp. MVY-004 and Its Significance for Biomineral Fertilizers’ Development in Agrobiotechnology
  19. 31479
    “…Additionally, we collated 217 publicly available CG147 genomes [National Center for Biotechnology Information (NCBI), May 2019]. CG147 evolution was inferred within a temporal phylogenetic framework (beast) based on a recombination-free sequence alignment (Roary/Gubbins). …”
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    Genomic evolution of the globally disseminated multidrug-resistant Klebsiella pneumoniae clonal group 147
  20. 31480
    “…FUNDING: Department of Biotechnology, India; Bill & Melinda Gates Foundation, USA…”
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    Sub-optimal neutralisation of omicron (B.1.1.529) variant by antibodies induced by vaccine alone or SARS-CoV-2 Infection plus vaccine (hybrid immunity) post 6-months
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