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  1. 26581
    “…This line of research may serve as a fundament for future studies linking these two revolutionary biotechnologies.…”
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    Application possibilities of artificial intelligence in facial vascularized composite allotransplantation—a narrative review
  2. 26582
    “…These studies explored different aspects of molecular mechanisms involved in plant stress tolerance, establishing comparative analyses among genotypes/cultivars to identify potential molecular markers of stresses that are now available for future application in biotechnological studies. This SI presents a collection of advanced concepts and emerging strategies for readers and researchers aiming to accelerate plant breeding.…”
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    Molecular Basis of Crops and Fruit Plants in Response to Stress
  3. 26583
    “…This is the reason why hybrid proteins containing ubiquitin at their N-end cannot be used in large scale biotechnological processes. RESULTS AND CONCLUSION: We have described the synthesis of the yeast deubiquination enzyme UBP1 muteins in E. coli. …”
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    Expression of yeast deubiquitination enzyme UBP1 analogues in E. coli
  4. 26584
    “…The newly discovered NHase might open biotechnological routes due to its unconventional structure, its new type of host and its apparent integration into eukaryotic protein networks.…”
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    A Nitrile Hydratase in the Eukaryote Monosiga brevicollis
  5. 26585
    “…H. orenii can serve as a model organism for the study of the evolution of the Gram negative phenotype as well as the adaptation under thermohalophilic conditions and the development of biotechnological applications under conditions that require high temperatures and high salt concentrations.…”
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    Genome Analysis of the Anaerobic Thermohalophilic Bacterium Halothermothrix orenii
  6. 26586
    “…The results of this study suggest that the two biotechnologically valuable products, lipase and CA, could be produced simultaneously by this strain using renewable low-cost substrates such as plant oils in one procedure.…”
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    Effect of Plant Oils upon Lipase and Citric Acid Production in Yarrowia lipolytica Yeast
  7. 26587
    “…The method of Ig elimination by extracorporeal immunoadsorption (IA) is a clinical application of the recent biotechnological advances. It offers an effective and safe therapy for severe MG even when the disease is resistant to standard therapy.…”
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    Extracorporeal Immunoglobulin Elimination for the Treatment of Severe Myasthenia Gravis
  8. 26588
    por Da Sacco, Letizia, Masotti, Andrea
    Publicado 2010
    “…Moreover, chitin and chitosan have been also used in biomedical and biotechnological applications as drug delivery systems or in pharmaceutical formulations. …”
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    Chitin and Chitosan as Multipurpose Natural Polymers for Groundwater Arsenic Removal and As(2)O(3) Delivery in Tumor Therapy
  9. 26589
    “…As water buffalo and domestic cattle, both members of the Bovidae family, are closely related, the vast amount of cattle genetic/genomic resources might serve as shortcuts for the buffalo community to further advance genome science and biotechnologies in the species.…”
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    Water Buffalo Genome Science Comes of Age
  10. 26590
    “…Fungi are of primary ecological, biotechnological and economic importance. Many fundamental biological processes that are shared by animals and fungi are studied in fungi due to their experimental tractability. …”
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    Effector diversification within compartments of the Leptosphaeria maculans genome affected by Repeat-Induced Point mutations
  11. 26591
    “…Production of keratinases by A. niger is a less-exploited field that might represent a novel and promising biotechnological application for this microorganism.…”
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    Production of Proteolytic Enzymes by a Keratin-Degrading Aspergillus niger
  12. 26592
    por Kell, Douglas B
    Publicado 2012
    “…A considerable number of areas of bioscience, including gene and drug discovery, metabolic engineering for the biotechnological improvement of organisms, and the processes of natural and directed evolution, are best viewed in terms of a ‘landscape’ representing a large search space of possible solutions or experiments populated by a considerably smaller number of actual solutions that then emerge. …”
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    Scientific discovery as a combinatorial optimisation problem: How best to navigate the landscape of possible experiments?
  13. 26593
    “…Inspired in a synthetic biology approach, the model was used for exploring the landscape of all possible local transcriptional changes with the aim of engineering tomato fruits with fine-tuned biotechnological properties. The method was validated by the ability of the proposed genomes, engineered for modified desired agronomic traits, to recapitulate experimental correlations between associated metabolites.…”
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    Fine-Tuning Tomato Agronomic Properties by Computational Genome Redesign
  14. 26594
    “…In particular, the kinetics of annealing between two imperfectly matched strands is not well characterized despite its potential importance in nucleic acids-based biotechnologies and gene silencing. Here we use single molecule fluorescence to visualize the multiple annealing and melting reactions of two untethered strands inside a porous vesicle, allowing us to quantify precisely the annealing and melting rates. …”
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    A rule of seven in Watson-Crick base pairing of mismatched sequences
  15. 26595
    “…ABA is also the central regulator to protect plants against abiotic stresses, such as drought, high salinity, and adverse temperatures, and ABA signaling is therefore a promising biotechnological target for the generation of crops with increased stress resistance. …”
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    Abscisic Acid Signaling: Thermal Stability Shift Assays as Tool to Analyze Hormone Perception and Signal Transduction
  16. 26596
    “…As Escherichia coli currently remains the predominant host organism used for recombinant prokaryotic protein expression, the generation of a strain that exhibits inducible flagellar secretion would be highly desirable for biotechnological applications. Here, we report the first engineered Escherichia coli mutant strain featuring flagellar morphogenesis upon addition of an external inducer. …”
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    FlgM as a Secretion Moiety for the Development of an Inducible Type III Secretion System
  17. 26597
    “…Enzyme application in biotechnological and environmental processes has had increasing interest due to its efficiency, selectivity and mainly for being environmentally healthful, but these applications require a great volume of enzymes. …”
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    Production of laccase by Pynoporus sanguineus using 2,5 - Xylidine and ethanol
  18. 26598
    “…After a brief description of the applications of vanillin in different industrial sectors and of its physicochemical properties, we described the traditional ways of providing vanillin, specifically extraction and chemical synthesis (mainly oxidation) and compared them with the new biotechnological options, i.e., biotransformations of caffeic acid, veratraldehyde and mainly ferulic acid. …”
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    Microbial Production of Biovanillin
  19. 26599
    “…Among metabolites produced by sponge-associated microbial communities, halogenated compounds are of special interest because of their biotechnological potential. In this study, we have examined the diversity of the cultivable fraction of the marine demosponge Crambe crambe microbiota. …”
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    Culture-dependent and independent approaches for identifying novel halogenases encoded by Crambe crambe (marine sponge) microbiota
  20. 26600
    “…Downstream processing is an important aspect of all biotechnological processes and has significant implications on quality and yield of the final product. …”
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    Development of Suitable Solvent System for Downstream Processing of Biopolymer Pullulan Using Response Surface Methodology
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