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27261por Rodríguez, Javier M., Allende-Ballestero, Carolina, Cornelissen, Jeroen J. L. M., Castón, José R.“…These characteristics render encapsulin an excellent platform for the development of biotechnological applications. Here we provide an overview of current knowledge of encapsulin systems, summarize the remarkable toolbox developed by researchers in this field, and discuss recent advances in the biomedical and bioengineering applications of encapsulins.…”
Publicado 2021
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27262por Lovell, John T., Bentley, Nolan B., Bhattarai, Gaurab, Jenkins, Jerry W., Sreedasyam, Avinash, Alarcon, Yanina, Bock, Clive, Boston, Lori Beth, Carlson, Joseph, Cervantes, Kimberly, Clermont, Kristen, Duke, Sara, Krom, Nick, Kubenka, Keith, Mamidi, Sujan, Mattison, Christopher P., Monteros, Maria J., Pisani, Cristina, Plott, Christopher, Rajasekar, Shanmugam, Rhein, Hormat Shadgou, Rohla, Charles, Song, Mingzhou, Hilaire, Rolston St., Shu, Shengqiang, Wells, Lenny, Webber, Jenell, Heerema, Richard J., Klein, Patricia E., Conner, Patrick, Wang, Xinwang, Grauke, L. J., Grimwood, Jane, Schmutz, Jeremy, Randall, Jennifer J.“…Genome-enabled biotechnologies have the potential to accelerate breeding efforts in long-lived perennial crop species. …”
Publicado 2021
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27263por Li, Qingxin“…Despite of some progress made in isolating keratinase-producing microorganisms, structural studies of keratinases, and biochemical characterization of these enzymes, effort is still required to expand the biotechnological application of keratinase in diverse fields by identifying more keratinases, understanding the mechanism of action and constructing more active enzymes through molecular biology and protein engineering. …”
Publicado 2021
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27264“…Intensive progress in the development of this group of materials offers an opportunity to create new systems useful for drinking water decontamination or other biotechnological applications. Nanohybrid structures of graphene-ceramic systems can be obtained using covalent graphene surface modification with nanoparticles (NPs) of ceramic and/or co-deposition of metals with selected morphology and chemistry. …”
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27265por Coutinho, Felipe Hernandes, Zaragoza-Solas, Asier, López-Pérez, Mario, Barylski, Jakub, Zielezinski, Andrzej, Dutilh, Bas E., Edwards, Robert, Rodriguez-Valera, Francisco“…RaFAH was applied to assembled metagenomic datasets of uncultured viruses from eight different biomes of medical, biotechnological, and environmental relevance. Our analyses led to the identification of 537 sequences of archaeal viruses representing unknown lineages, whose genomes encode novel auxiliary metabolic genes, shedding light on how these viruses interfere with the host molecular machinery. …”
Publicado 2021
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27266por Musil, Milos, Khan, Rayyan Tariq, Beier, Andy, Stourac, Jan, Konegger, Hannes, Damborsky, Jiri, Bednar, David“…There is a great interest in increasing proteins’ stability to widen their usability in numerous biomedical and biotechnological applications. However, native proteins cannot usually withstand the harsh industrial environment, since they are evolved to function under mild conditions. …”
Publicado 2020
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27267“…Debaryomyces hansenii yeast represents a promising target for basic and applied biotechnological research It is known that D. hansenii is abundant in sausages and dry-meat products, but information regarding its contribution to their characteristics is blurry and contradictory. …”
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27268“…It also aims to provide synthetic and biotechnological approaches based on combinatorial biochemical and protein engineering to synthesize phytocannabinoids with enhanced properties.…”
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27269por Bertani, Iris, Zampieri, Elisa, Bez, Cristina, Volante, Andrea, Venturi, Vittorio, Monaco, Stefano“…The development of biotechnologies based on beneficial microorganisms for improving soil fertility and crop yields could help to address many current agriculture challenges, such as food security, climate change, pest control, soil depletion while decreasing the use of chemical fertilizers and pesticides. …”
Publicado 2021
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27270por Sulej, Justyna, Jaszek, Magdalena, Osińska-Jaroszuk, Monika, Matuszewska, Anna, Bancerz, Renata, Janczarek, Monika“…In summary, natural polysaccharides seem to be an effective biotechnological tool for the modification of CDH activity to increase the possibilities of its practical applications in many fields of industry.…”
Publicado 2021
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27271“…Acoustic tweezing of bioparticles has distinct advantages over other manipulation methods such as electrophoresis or magnetophoresis in biotechnological applications. This manipulation method guarantees the viability of the bio-particles during and after the process. …”
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27272“…As one of the largest biotechnological applications, activated sludge (AS) systems in wastewater treatment plants (WWTPs) harbor enormous viruses, with 10-1,000-fold higher concentrations than in natural environments. …”
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27273por Komarevtsev, Sergei K., Evseev, Peter V., Shneider, Mikhail M., Popova, Elizaveta A., Tupikin, Alexey E., Stepanenko, Vasiliy N., Kabilov, Marsel R., Shabunin, Sergei V., Osmolovskiy, Alexander A., Miroshnikov, Konstantin A.“…Micromycetes are known to secrete numerous enzymes of biotechnological and medical potential. Fibrinolytic protease-activator of protein C (PAPC) of blood plasma from micromycete Aspergillus ochraceus VKM-F4104D was obtained in recombinant form utilising the bacterial expression system. …”
Publicado 2021
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27274por Geisler, Katrin, Scaife, Mark A., Mordaka, Paweł M., Holzer, Andre, Tomsett, Eleanor V., Mehrshahi, Payam, Mendoza Ochoa, Gonzalo I., Smith, Alison G.“…Chlamydomonas reinhardtii has many attractive features for use as a model organism for both fundamental studies and as a biotechnological platform. Nonetheless, despite the many molecular tools and resources that have been developed, there are challenges for its successful engineering, in particular to obtain reproducible and high levels of transgene expression. …”
Publicado 2021
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27275por López-Laguna, Hèctor, Sánchez, Julieta M., Carratalá, José Vicente, Rojas-Peña, Mauricio, Sánchez-García, Laura, Parladé, Eloi, Sánchez-Chardi, Alejandro, Voltà-Durán, Eric, Serna, Naroa, Cano-Garrido, Olivia, Flores, Sandra, Ferrer-Miralles, Neus, Nolan, Verónica, de Marco, Ario, Roher, Nerea, Unzueta, Ugutz, Vazquez, Esther, Villaverde, Antonio“…Since most of the recombinant proteins produced by biochemical and biotechnological industries and intended for biomedical research are His-tagged, the green biofabrication procedure proposed here can be straightforwardly applied to a huge spectrum of protein species for their conversion into their respective nanostructured formats.…”
Publicado 2021
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27276por de Camargo, Brenda R., da Silva, Leonardo A., de Oliveira, Athos S., Ribeiro, Bergmann M.“…The COVID-19 pandemic has demanded a range of biotechnological products for detection of SARS-CoV-2 variants and evaluation of human seroconversion after infection or vaccination. …”
Publicado 2022
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27277por Semenyuk, Pavel I., Kurochkina, Lidia P., Mäkinen, Lauri, Muronetz, Vladimir I., Hietala, Sami“…Complexation also partially protected lysozyme from proteolytic degradation by proteinase K, which is useful for biotechnological applications. The obtained results are relevant for important medicinal tasks associated with drug delivery such as the delivery and controlled release of enzyme-based drugs.…”
Publicado 2021
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27278por Herbrand, Cathy“…This article therefore calls for more systematic use of an integrated analytical framework of ignorance to be applied in the field of reproductive public policies, paying particular attention not only to the ways that medical risks are addressed, but also to the type of knowledge and disciplines this allows to silence or side-line in the framing and assessment of new biotechnologies.…”
Publicado 2021
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27279por Paolo, Dario, Locatelli, Franca, Cominelli, Eleonora, Pirona, Raul, Pozzo, Sara, Graziani, Giulia, Ritieni, Alberto, De Palma, Monica, Docimo, Teresa, Tucci, Marina, Sparvoli, Francesca“…As high lignin content determines lower saccharification yields for the biomass, we opted for a biotechnological approach, with the purpose of reducing lignin content; we generated transgenic lines overexpressing the Arabidopsis thaliana MYB4 transcription factor, a known repressor of lignin/flavonoid biosynthesis. …”
Publicado 2021
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27280“…The yeast Saccharomyces cerevisiae is extensively used to study iron and lipid metabolisms, as well as in multiple biotechnological applications. Despite iron being indispensable for yeast ergosterol biosynthesis and growth, little is known about their interconnections. …”
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