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  1. 27661
    “…Our results demonstrate that molecular mimicry of CRISPR repeats is a widespread anti-CRISPR strategy, which opens the door to potential biotechnological applications(6).…”
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    Bacteriophages suppress CRISPR–Cas immunity using RNA-based anti-CRISPRs
  2. 27662
    “…Colony formation is key to many ecological and biotechnological processes. In its early stages, colony formation involves the concourse of a number of physical and biological parameters for generation of a distinct 3D structure—the specific influence of which remains unclear. …”
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    Pressure‐dependent growth controls 3D architecture of Pseudomonas putida microcolonies
  3. 27663
    “…In addition, despite hindering insecticide management programs, they still have several biotechnological uses, including industrial, clinical, and environmental uses. …”
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    Insect Microbial Symbionts: Ecology, Interactions, and Biological Significance
  4. 27664
    “…Traditional studies have focused on the toxic cyanotoxins produced by harmful cyanobacteria, which pose a risk to both human beings and wildlife, causing acute and chronic poisoning, resulting in diarrhea, nerve paralysis, and proliferation of cancer cells. Actually, the biotechnological potential of cyanotoxins is underestimated, as increasing studies have demonstrated their roles as valuable products, including allelopathic agents, insecticides and biomedicines. …”
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    Recent Advances in Cyanotoxin Synthesis and Applications: A Comprehensive Review
  5. 27665
    por Rutherford, Nancy, Mourez, Michael
    Publicado 2006
    “…Expressing proteins of interest as fusions to proteins of the bacterial envelope is a powerful technique with many biotechnological and medical applications. Autotransporters have recently emerged as a good tool for bacterial surface display. …”
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    Surface display of proteins by Gram-negative bacterial autotransporters
  6. 27666
    “…By applying MCA it is possible to identify the steps that should be modified to achieve a successful alteration of flux or metabolite concentration in pathways of biotechnological (e.g., large scale metabolite production) or clinical relevance (e.g., drug therapy). …”
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    Metabolic Control Analysis: A Tool for Designing Strategies to Manipulate Metabolic Pathways
  7. 27667
    por Suzuki, Hiroaki, Takeuchi, Shoji
    Publicado 2008
    “…Despite the rapid and enormous progress in biotechnologies, the biochemical analysis of membrane proteins is still a difficult task. …”
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    Microtechnologies for membrane protein studies
  8. 27668
    por Dayie, Kwaku T.
    Publicado 2008
    “…Therefore, various methods for introducing probes for structural, functional, and biotechnological applications are critically assessed here. …”
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    Key Labeling Technologies to Tackle Sizeable Problems in RNA Structural Biology
  9. 27669
    “…Cellular response to the Sdhp dysfunction (i.e. impaired respiration) thus has important implications not only for biotechnological applications but also for understanding cellular physiology underlying metabolic diseases such as diabetes. …”
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    Global transcriptional response of Saccharomyces cerevisiae to the deletion of SDH3
  10. 27670
    “…The use of biotechnological techniques to introduce novel proteins into food crops (transgenic or GM crops) has motivated investigation into the properties of proteins that favor their potential to elicit allergic reactions. …”
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    Value of eight-amino-acid matches in predicting the allergenicity status of proteins: an empirical bioinformatic investigation
  11. 27671
    “…CONCLUSIONS: Our study provides the first detailed insights into the complex sequence of early regulatory events during and preceding the major metabolic switch in S. coelicolor, which will form the starting point for future attempts at engineering antibiotic production in a biotechnological setting.…”
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    The dynamic architecture of the metabolic switch in Streptomyces coelicolor
  12. 27672
    “…In addition the results support the feasibility of using evolutionary information to achieve protein multi-feature optimization, an important biotechnological goal.…”
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    Role of conservative mutations in protein multi-property adaptation
  13. 27673
    por Seiboth, Bernhard, Metz, Benjamin
    Publicado 2011
    “…The genes and encoding enzymes l-arabinose reductase, l-arabinitol dehydrogenase, l-xylulose reductase, xylitol dehydrogenase, and xylulokinase of this pathway were mainly characterized in the two biotechnological important fungi Aspergillus niger and Trichoderma reesei. …”
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    Fungal arabinan and l-arabinose metabolism
  14. 27674
    “…They catalyze the oxidation of many, particularly phenolic substances, and, besides playing an important role in many cellular activities, are of interest in biotechnological applications. The Laccase Engineering Database (LccED, http://www.lcced.uni-stuttgart.de) was designed to serve as a tool for a systematic sequence-based classification and analysis of the diverse multicopper oxidase protein family. …”
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    The Laccase Engineering Database: a classification and analysis system for laccases and related multicopper oxidases
  15. 27675
    “…Here we demonstrate efficient site-specific recombination at several sequences taken from a 1.9 kilobasepair locus of biotechnological interest (in the bovine β-casein gene), mediated by zinc finger recombinases (ZFRs), chimaeric enzymes with linked zinc finger (DNA recognition) and recombinase (catalytic) domains. …”
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    Zinc Finger Recombinases with Adaptable DNA Sequence Specificity
  16. 27676
    “…This volatile profiling platform for Citrus juice by HS-SPME-GC-MS and the interrelationship detected among the volatiles can be used as a roadmap for future breeding or biotechnological applications.…”
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    Comparative Analysis of the Volatile Fraction of Fruit Juice from Different Citrus Species
  17. 27677
    “…The information regarding enzyme induction will be important to optimize the production by the bacterial isolates, which may be a great value for biotechnological applications.…”
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    Amylolytic Microorganism from São Paulo Zoo Composting: Isolation, Identification, and Amylase Production
  18. 27678
    “…New post genomic biotechnologies such as transcriptome analyses are efficient in characterising the pool of genes involved in the expression of specific biological functions. …”
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    Serial analysis of gene expression (SAGE) in bovine trypanotolerance: preliminary results
  19. 27679
    “…The ascomycete fungus Fusarium fujikuroi (Gibberella fujikuroi MP-C) produces secondary metabolites of biotechnological interest, such as gibberellins, bikaverin, and carotenoids. …”
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    Adenylyl Cyclase Plays a Regulatory Role in Development, Stress Resistance and Secondary Metabolism in Fusarium fujikuroi
  20. 27680
    por Amirkia, Vafa, Qiubao, Pan
    Publicado 2012
    “…Cultivation of primary cells is essential for biotechnological research and viral vaccine production. …”
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    Cell-culture Database: Literature-based reference tool for human and mammalian experimentallybased cell culture applications
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