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  1. 28041
    por Rennie, Stuart, Mupenda, Bavon
    Publicado 2008
    “…Although these inequalities, as well as attempts to improve sub-standard health, raise profound issues of social justice and the right to health, those working in the field of bioethics have historically tended to devote greater attention to ethical issues raised by new, cutting-edge biotechnologies such as life-support cessation, genomics, stem cell research or face transplantation. …”
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    Living apart together: reflections on bioethics, global inequality and social justice
  2. 28042
    “…Although many secondary metabolites with diverse biological activities have been isolated from myxobacteria, most strains of these biotechnologically important gliding prokaryotes remain difficult to handle genetically. …”
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    Novel expression hosts for complex secondary metabolite megasynthetases: Production of myxochromide in the thermopilic isolate Corallococcus macrosporus GT-2
  3. 28043
    “…BACKGROUND: Cytochrome P450 monooxygenases (CYPs) form a vast and diverse enzyme class of particular interest in drug development and a high biotechnological potential. Although very diverse in sequence, they share a common structural fold. …”
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    The Cytochrome P450 Engineering Database: integration of biochemical properties
  4. 28044
    “…The efficient deglycosylation of Png1p-ΔH1 towards native and non-native glycoproteins offers a potential biotechnological application.…”
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    N-Terminal Deletion of Peptide:N-Glycanase Results in Enhanced Deglycosylation Activity
  5. 28045
    “…Attempts to exploit these catalysts in engineered systems have been hindered by the biotechnologically inconvenient properties of the natural enzymes, including their extreme oxygen sensitivity. …”
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    A Cell-Free Microtiter Plate Screen for Improved [FeFe] Hydrogenases
  6. 28046
    “…These results constitute a “proof-of-concept” for custom-designing promoters that are suitable for biotechnological and medical applications.…”
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    Exploiting Nucleotide Composition to Engineer Promoters
  7. 28047
    “…In parallel to these studies, we wish to introduce these unique biotechnologies for use in the basic biological sciences, for handling a wide range of cell types and systems, thus increasing the range and the scope of these techniques for modern research. …”
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    Online Artículo Texto
    Bio-electrospraying and aerodynamically assisted bio-jetting the model eukaryotic Dictyostelium discoideum: assessing stress and developmental competency post treatment
  8. 28048
    “…Therefore, this inexpensive lipase production for such a potent and industrially valuable lipase is promising and of considerable commercial interest for biotechnological applications.…”
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    Online Artículo Texto
    Production of a Solvent, Detergent, and Thermotolerant Lipase by a Newly Isolated Acinetobacter sp. in Submerged and Solid-State Fermentations
  9. 28049
    “…Fungi are known to be involved in many degradative processes, including the breakdown of petroleum hydrocarbons, and it has been speculated that in Polar Regions they contribute significantly to bioremediation of contaminated soils. Given the biotechnological potential of fungi there is a need to increase efforts for greater species recovery, particularly from extreme environments such as sub-Antarctic Macquarie Island. …”
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    Recovering Greater Fungal Diversity from Pristine and Diesel Fuel Contaminated Sub-Antarctic Soil Through Cultivation Using Both a High and a Low Nutrient Media Approach
  10. 28050
    por Muzaffar, Mahvish, Ahmad, Atta
    Publicado 2011
    “…The high propensity of insulin to fibrillate causes severe biomedical and biotechnological complications. Insulin fibrillation studies attain significant importance considering the prevalence of diabetes and the requirement of functional insulin in each dose. …”
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    The Mechanism of Enhanced Insulin Amyloid Fibril Formation by NaCl Is Better Explained by a Conformational Change Model
  11. 28051
    “…In order to study HIV subtype biology and to provide a tool for biotechnological applications, the first full-length replication-competent infectious molecular clone harboring CRF08_BC is reported. …”
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    Parental LTRs Are Important in a Construct of a Stable and Efficient Replication-Competent Infectious Molecular Clone of HIV-1 CRF08_BC
  12. 28052
    “…BACKGROUND: Genome-scale metabolic network models have contributed to elucidating biological phenomena, and predicting gene targets to engineer for biotechnological applications. With their increasing importance, their precise network characterization has also been crucial for better understanding of the cellular physiology. …”
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    Framework for network modularization and Bayesian network analysis to investigate the perturbed metabolic network
  13. 28053
    “…Methanogenic archaeans are organisms of considerable ecological and biotechnological interest that produce methane through a restricted metabolic pathway, which culminates in the reaction catalyzed by the Methyl-coenzyme M reductase (Mcr) enzyme, and results in the release of methane. …”
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    Diversity and three-dimensional structures of the alpha Mcr of the methanogenic Archaea from the anoxic region of Tucuruí Lake, in Eastern Brazilian Amazonia
  14. 28054
    “…In addition, this volatile network of interactions provides the ground information for future biochemical studies as well as a useful route map for breeding or biotechnological purposes.…”
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    A Non-Targeted Approach Unravels the Volatile Network in Peach Fruit
  15. 28055
    “…Our data suggest the important role of indirect readout in this substrate region, opening the possibility for a fully rational search of new target sequences, thus improving the development of redesigned enzymes for therapeutic and biotechnological applications.…”
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    Non-specific protein–DNA interactions control I-CreI target binding and cleavage
  16. 28056
    “…BACKGROUND: Yarrowia lipolytica is an oleaginous yeast which has emerged as an important microorganism for several biotechnological processes, such as the production of organic acids, lipases and proteases. …”
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    A genome-scale metabolic model of the lipid-accumulating yeast Yarrowia lipolytica
  17. 28057
    “…Because of their biotechnological potential, lectins are widely used in biomedical research. …”
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    Characterization of Isoforms of the Lectin Isolated from the Red Algae Bryothamnion seaforthii and Its Pro-Healing Effect
  18. 28058
    “…The simultaneous biomass increase with the detoxification of a toxic phenolic compound (p-cresol) could be a significant biotechnological aspect for further applications.…”
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    Bioenergetic Strategy for the Biodegradation of p-Cresol by the Unicellular Green Alga Scenedesmus obliquus
  19. 28059
    “…Fungi produce α-aminoadipate, a precursor for penicillin and lysine via the α-aminoadipate pathway. Despite the biotechnological importance of this pathway, the essential isomerization of homocitrate via homoaconitate to homoisocitrate has hardly been studied. …”
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    The fungal α-aminoadipate pathway for lysine biosynthesis requires two enzymes of the aconitase family for the isomerization of homocitrate to homoisocitrate
  20. 28060
    “…This study provides insights in the QS-regulated functions of a PGPR, which could lead to beneficial potential biotechnological applications.…”
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    Identification of quorum sensing-controlled genes in Burkholderia ambifaria
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