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  1. 28661
    “…Major metabolic perturbations were caused by the TF AtMYB12, affecting both primary and secondary metabolism, which confirms the complexity of biotechnological systems based on seed plant in vitro cultures for the heterologous production of high-value molecules.…”
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    Tailoring tobacco hairy root metabolism for the production of stilbenes
  2. 28662
    “…Strain E4A9(T) encodes 10 genes related to esterase, and three of the esterases (E3, E6 and E10) was successfully cloned and expressed in Escherichia coli Rosetta in a soluble form, revealing its potential application in biotechnological industry. Moreover, the genome provides clues of metabolic pathways of strain E4A9(T), reflecting its adaptations to the ambient environment. …”
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    Complete genome sequence of esterase-producing bacterium Croceicoccus marinus E4A9(T)
  3. 28663
    “…Recombinant therapeutic proteins that are manufactured using biotechnological processes are prone to LPS contaminations due to their ubiquitous occurrence. …”
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    Biophysical Analysis of Lipopolysaccharide Formulations for an Understanding of the Low Endotoxin Recovery (LER) Phenomenon
  4. 28664
    “…However, drug safety research has been progressing slowly in recent years, compared to other fields such as biotechnologies and precision medicine, due to the mechanistic complexity of adverse drug reactions (ADRs). …”
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    ADReCS-Target: target profiles for aiding drug safety research and application
  5. 28665
    “…BACKGROUND: Yarrowia lipolytica is a common biotechnological chassis for the production of lipids, which are the preferred feedstock for the production of fuels and chemicals. …”
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    Engineering Yarrowia lipolytica to enhance lipid production from lignocellulosic materials
  6. 28666
    “…RESULTS: There may be barriers to effective communication between healthcare personnel and patients, depending on the characteristics of the persons involved, the organisation of healthcare, biotechnological progress and cultural factors. CONCLUSIONS: The human quality of healthcare has deteriorated due to excessive workloads and to the growing role played by technology. …”
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    Breaking bad news to antenatal patients with strategies to lessen the pain: a qualitative study
  7. 28667
    “…This novel deacetylation pattern expands our toolbox of specific CDAs for biotechnological applications, and will provide further insights into the determinants of substrate specificity in this family of enzymes.…”
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    Expression and specificity of a chitin deacetylase from the nematophagous fungus Pochonia chlamydosporia potentially involved in pathogenicity
  8. 28668
    “…This has enabled us to study its specificity and test its suitability for biotechnological applications. The ability of soluble NisP to cleave leaders from various substrates was tested with two sets of nisin variants. …”
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    Specificity and Application of the Lantibiotic Protease NisP
  9. 28669
    “…CONCLUSIONS: The identification of this subclass of plant immune receptors that is naturally adapted to new domain integration will inform biotechnological approaches for generating synthetic receptors with novel pathogen “baits.” …”
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    Dominant integration locus drives continuous diversification of plant immune receptors with exogenous domain fusions
  10. 28670
    “…Using combinatorial approaches, these molecular recognition elements can be converted into smart hybrid biomaterials and harnessed for biotechnological applications. Herein, we used a commercially available phage-display library to identify peptides with specific binding affinity to molybdenite (MoS(2)) and used them to decorate magnetic NPs. …”
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    Biomining of MoS(2) with Peptide-based Smart Biomaterials
  11. 28671
    “…These extremophiles are commonly isolated from the same habitats in Earth’s cryosphere and have great ecological and biotechnological relevance. Thus, through comparative genomic analyses, it was possible to understand the functional diversity of these psychrotrophic and psychrophilic species and present new insights into the microbial adaptation to cold. …”
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    Genomic Architecture of the Two Cold-Adapted Genera Exiguobacterium and Psychrobacter: Evidence of Functional Reduction in the Exiguobacterium antarcticum B7 Genome
  12. 28672
    “…We expect that the continuous and careful annotation of L. fortunei’s genome will contribute to the investigation of bivalve genetics, evolution, and invasiveness, as well as to the development of biotechnological tools for aquatic pest control.…”
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    A hybrid-hierarchical genome assembly strategy to sequence the invasive golden mussel, Limnoperna fortunei
  13. 28673
    por Liu, Deng, Pakrasi, Himadri B.
    Publicado 2018
    “…However, as a green chassis to capture CO(2) for biotechnological applications, the genetic toolbox for Synechocystis 6803 is still a limited factor. …”
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    Exploring native genetic elements as plug-in tools for synthetic biology in the cyanobacterium Synechocystis sp. PCC 6803
  14. 28674
    “…The scientific community is using CRISPR/Cas9 for various biotechnological and medical purposes. One of its most important uses is developing potential therapeutic strategies against diseases. …”
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    CRISPR/Cas9: the Jedi against the dark empire of diseases
  15. 28675
    por Freudl, Roland
    Publicado 2018
    “…The secretion of biotechnologically or pharmaceutically relevant recombinant proteins into the culture supernatant of a bacterial expression host greatly facilitates their downstream processing and significantly reduces the production costs. …”
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    Signal peptides for recombinant protein secretion in bacterial expression systems
  16. 28676
    “…Meristem plant cell cultures elicited by solar simulating UV could be the most environmentally sustainable biotechnological source of polyphenols with combined photoprotective and antiaging properties.…”
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    Natural Substances for Prevention of Skin Photoaging: Screening Systems in the Development of Sunscreen and Rejuvenation Cosmetics
  17. 28677
    “…These results demonstrate the significance of Streptomyces inhabiting the arid region of Thar Desert, suggesting that similar arid environments can be considered as the reservoirs of novel Streptomyces strains that could have biotechnological significance.…”
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    Biosynthetic Potential of Bioactive Streptomycetes Isolated From Arid Region of the Thar Desert, Rajasthan (India)
  18. 28678
    “…Our results indicate that these six strawberry NAC proteins could play different important regulatory roles in the process of development and ripening of the fruit, providing the basis for further functional studies and the selection for NAC candidates suitable for biotechnological applications.…”
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    Genome-wide analysis of the NAC transcription factor family and their expression during the development and ripening of the Fragaria × ananassa fruits
  19. 28679
    “…CONCLUSIONS: The results shown here indicate that VOCs released by bacteria isolated from human facial skin have a potential for biotechnological uses as a strategy to prevent the vectorial transmission of Chagas disease mediated by Rhodnius prolixus.…”
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    Behavioral responses of Rhodnius prolixus to volatile organic compounds released in vitro by bacteria isolated from human facial skin
  20. 28680
    “…Notably, recent biotechnological breakthroughs in the understanding of gene functions and access to whole genome sequences have opened new avenues for crop improvement. …”
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    Abiotic Stress Signaling in Wheat – An Inclusive Overview of Hormonal Interactions During Abiotic Stress Responses in Wheat
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