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  1. 29421
    “…This study is a step forward in the biotechnological development and implementation of storable mediatorless electrochemical biosensors for herbicide detection.…”
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    A Storable Mediatorless Electrochemical Biosensor for Herbicide Detection
  2. 29422
    “…In this review, various aspects of the CRISPR/Cas9 system are explored, including a general presentation of the function of the CRISPR/Cas9 system in bacteria and its practical application as a biotechnological tool for editing plant genomes, particularly in horticultural crops.…”
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    Development of Improved Fruit, Vegetable, and Ornamental Crops Using the CRISPR/Cas9 Genome Editing Technique
  3. 29423
    “…Lipases comprise a large class of hydrolytic enzymes which catalyze the cleavage of the ester bonds in triacylglycerols and find numerous biotechnological applications. Previously, we have cloned the gene coding for a novel esterase PMGL2 from a Siberian permafrost metagenomic DNA library. …”
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    Crystal structure of PMGL2 esterase from the hormone-sensitive lipase family with GCSAG motif around the catalytic serine
  4. 29424
    “…CONCLUSION: Our study elucidates the early steps of celastrol biosynthesis and paves the way for future biotechnological production of this pharmacologically promising compound in engineered yeast strains.…”
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    Integrating pathway elucidation with yeast engineering to produce polpunonic acid the precursor of the anti-obesity agent celastrol
  5. 29425
    “…They also have significant potential as organismal platforms for exploitation to address biotechnological and industrial goals. In order to address both modes of research, sophisticated molecular and genetic tools are required. …”
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    Multiplexed Knockouts in the Model Diatom Phaeodactylum by Episomal Delivery of a Selectable Cas9
  6. 29426
    “…Some gibberellin-dependent genes encode enzymes coordinating the biosynthesis of tanshinones: diterpene derivatives with broad medical applications. New biotechnological approaches, such as metabolic engineering using naturally occurring or mutated enzymes, have been proposed to meet the growing demand for tanshinones which is currently met by the Chinese medicinal plant Salvia miltiorrhiza Bunge. …”
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    Computer-Aided Saturation Mutagenesis of Arabidopsis thaliana Ent-Copalyl Diphosphate Synthase
  7. 29427
    “…Cutaneous secretions of amphibians have bioactive compounds, such as peptides, with potential for biotechnological applications. Therefore, this study aimed to determine the primary structure and investigate peptides obtained from the cutaneous secretions of the amphibian, Leptodactylus vastus, as a source of bioactive molecules. …”
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    Novel Ocellatin Peptides Mitigate LPS-induced ROS Formation and NF-kB Activation in Microglia and Hippocampal Neurons
  8. 29428
    “…Fusarium oxisporum (Fox) is a fungus of biotechnological importance due to its pathogenicity in different organisms, that is why the relevance of also biochemically analyzing its TPI, being the first report of its kind in a Fusarium. …”
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    Gene Cloning, Recombinant Expression, Characterization, and Molecular Modeling of the Glycolytic Enzyme Triosephosphate Isomerase from Fusarium oxysporum
  9. 29429
    “…Overall, our results imply that plant cell wall decomposition ability of taxonomically and ecologically divergent fungi is in line with their enzymatic decay strategy, which is fundamental in understanding their physiology and potential for biotechnological applications.…”
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    Enzyme Activity Profiles Produced on Wood and Straw by Four Fungi of Different Decay Strategies
  10. 29430
    “…Methanogenesis, a biological process mediated by complex microbial communities, has attracted great attention due to its contribution to global warming and potential in biotechnological applications. The current study unveiled the core microbial methanogenic metabolisms in anaerobic vessel ecosystems by applying combined genome-centric metagenomics and metatranscriptomics. …”
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    Metabolic dependencies govern microbial syntrophies during methanogenesis in an anaerobic digestion ecosystem
  11. 29431
    “…In most yeast-driven biotechnological applications, biomass is separated from the aqueous phase after fermentation or production has finished. …”
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    Identification of flocculant wine yeast strains with improved filtration-related phenotypes through application of high-throughput sedimentation rate assays
  12. 29432
    “…Sponge-associated bacteria possess biotechnologically interesting properties but as yet have largely evaded cultivation. …”
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    Cultivation of Bacteria From Aplysina aerophoba: Effects of Oxygen and Nutrient Gradients
  13. 29433
    “…Nanochannels are used in the biotechnological and environmental fields, being employed for DNA analysis and water purification, due to their unique features of capillary-induced negative pressure and an electrical double-layer overlap. …”
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    Fabrication of a Novel Nanofluidic Device Featuring ZnO Nanochannels
  14. 29434
    “…BV410 collected from the chamomile rhizosphere. The biotechnological production of staurosporine by strain BV410 was optimized to yield 56 mg/L after 14 days of incubation in soy flour–glucose–starch–mannitol‐based fermentation medium (JS). …”
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    Streptomyces sp. BV410 isolate from chamomile rhizosphere soil efficiently produces staurosporine with antifungal and antiangiogenic properties
  15. 29435
    “…Marine cyanobacteria are considered a prolific source of bioactive natural products with a range of biotechnological and pharmacological applications. However, data on the production of natural compounds from sponge-associated cyanobacteria are scarce. …”
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    Bioprospecting Sponge-Associated Marine Cyanobacteria to Produce Bioactive Compounds
  16. 29436
    “…Unfortunately, their biotechnological applications cannot be exploited to the level they deserve due to their axenically unculturable nature.…”
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    Interactions of Piriformospora indica with Medicinal Plants
  17. 29437
    “…Overall, the present work provides a feasible approach for the enhanced production of biologically active flavonoids in I. tinctoria hairy root cultures via the simple supplementation of ultraviolet-B radiation, which is useful for the biotechnological production of these high-added value compounds to fulfil the ever-increasing demand in pharmaceutical fields.…”
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    Ultraviolet radiation for flavonoid augmentation in Isatis tinctoria L. hairy root cultures mediated by oxidative stress and biosynthetic gene expression
  18. 29438
    “…The Ochrobactrum genus consists of an extensive repertoire of biotechnologically valuable bacterial strains but also opportunistic pathogens. …”
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    Identification and Characterization of the First Virulent Phages, Including a Novel Jumbo Virus, Infecting Ochrobactrum spp.
  19. 29439
    “…Furthermore, the biotransformation of various organic compounds has been investigated as a target in the biotechnological application of plant cell culture systems. …”
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    Glycosylation of Stilbene Compounds by Cultured Plant Cells
  20. 29440
    “…S-2 will elucidate its full biotechnological potential.…”
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    Genome Mining Revealed a High Biosynthetic Potential for Antifungal Streptomyces sp. S-2 Isolated from Black Soot
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