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29941por Nevermann, Jan, Silva, Andrés, Otero, Carolina, Oyarzún, Diego P., Barrera, Boris, Gil, Fernando, Calderón, Iván L., Fuentes, Juan A.“…Furthermore, OMVs can be used in biotechnological applications that require delivery of biomolecules, such as vaccines, remarking the importance of their study. …”
Publicado 2019
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29942por Moore, Bethany M., Wang, Peipei, Fan, Pengxiang, Leong, Bryan, Schenck, Craig A., Lloyd, John P., Lehti-Shiu, Melissa D., Last, Robert L., Pichersky, Eran, Shiu, Shin-Han“…Plant specialized metabolism (SM) enzymes produce lineage-specific metabolites with important ecological, evolutionary, and biotechnological implications. Using Arabidopsis thaliana as a model, we identified distinguishing characteristics of SM and GM (general metabolism, traditionally referred to as primary metabolism) genes through a detailed study of features including duplication pattern, sequence conservation, transcription, protein domain content, and gene network properties. …”
Publicado 2019
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29943por Canto-Pastor, Alex, Santos, Bruno A. M. C., Valli, Adrian A., Summers, William, Schornack, Sebastian, Baulcombe, David C.“…We also illustrate the use of STTM RNA in a biotechnological approach for enhancing quantitative disease resistance in highly bred cultivars.…”
Publicado 2019
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29944por Sodré, Victoria, Araujo, Juscemácia Nascimento, Gonçalves, Thiago Augusto, Vilela, Nathália, Braz, Antonio Sergio Kimus, Franco, Telma Teixeira, de Oliveira Neto, Mário, Damasio, André Ricardo de Lima, Garcia, Wanius, Squina, Fabio Marcio“…In this context, these enzymes are of biotechnological interest for conversion of lignin-derived FA into high value chemicals. …”
Publicado 2019
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29945por Choque, Elodie, Klopp, Christophe, Valiere, Sophie, Raynal, José, Mathieu, Florence“…BACKGROUND: Black Aspergilli represent one of the most important fungal resources of primary and secondary metabolites for biotechnological industry. Having several black Aspergilli sequenced genomes should allow targeting the production of certain metabolites with bioactive properties. …”
Publicado 2018
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29946“…INTRODUCTION: Stem cell research (SCR) and the biomedical potential of developing therapies are crucial topics in biomedicine. Like other biotechnologies, stem cells are context specific entities understood through local conceptualisations of culture, politics, nationhood, as well as their perceived therapeutic efficacy. …”
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29947por Berni, Roberto, Piasecki, Emilie, Legay, Sylvain, Hausman, Jean-Francois, Siddiqui, Khawar Sohail, Cai, Giampiero, Guerriero, Gea“…They have attracted a lot of interest for biotechnological applications in light of their eco-friendliness: they indeed oxidize the substrate(s) by coupling the four electron reduction of the final acceptor, molecular oxygen (O(2)), to water. …”
Publicado 2019
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29948“…The aim of this study is to understand the molecular basis behind these phenotypic differences of biotechnological interest by using a species-based comparative genomics approach. …”
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29949por Guzmán-Zapata, Daniel, Sandoval-Vargas, José M., Macedo-Osorio, Karla S., Salgado-Manjarrez, Edgar, Castrejón-Flores, José L., Oliver-Salvador, María del Carmen, Durán-Figueroa, Noé V., Nogué, Fabien, Badillo-Corona, Jesús A.“…This requires a constant source of RNPs and limits the application of the technology to strains that are not necessarily the most relevant from a biotechnological point of view. Here, we show that transient expression of the Streptococcus pyogenes Cas9 gene and sgRNAs, targeted to the single-copy nuclear apt9 gene, encoding an adenine phosphoribosyl transferase (APT), results in efficient disruption at the expected locus. …”
Publicado 2019
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29950“…Development in targeted imaging and therapeutic agents calls for close cooperation among academic environment and industries such as biotechnological, IT and pharmaceutical industries.…”
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29951“…BACKGROUND: In the last years, different biotechnologically relevant microorganisms have been engineered for the synthesis of plant polyphenols such as flavonoids and stilbenes. …”
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29952“…In order to elucidate the structure – function relationship of this enzyme and to apply biotechnological tools for enhancing the production of sesamin in the crop, it was intended to clone and express the enzyme in a heterologous system. …”
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29953por de Souza, Wagner Rodrigo, Pacheco, Thályta Fraga, Duarte, Karoline Estefani, Sampaio, Bruno Leite, de Oliveira Molinari, Patrícia Abrão, Martins, Polyana Kelly, Santiago, Thaís Ribeiro, Formighieri, Eduardo Fernandes, Vinecky, Felipe, Ribeiro, Ana Paula, da Cunha, Bárbara Andrade Dias Brito, Kobayashi, Adilson Kenji, Mitchell, Rowan Andrew Craig, de Sousa Rodrigues Gambetta, Dasciana, Molinari, Hugo Bruno Correa“…CONCLUSIONS: The silencing of SacBAHD01 gene and subsequent decrease of cell-wall ferulate contents indicate a promising novel biotechnological approach for improving the suitability of sugarcane residues for cellulosic ethanol production. …”
Publicado 2019
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29954“…Hence, there is great biotechnological interest in replacing the Rubisco in C(3) crops with a more efficient enzyme. …”
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29955por Yan, Qi, Liu, Nianjun, Forno, Erick, Canino, Glorisa, Celedón, Juan C., Chen, Wei“…The development of high-throughput biotechnologies allows the collection of omics data to study the biological mechanisms underlying complex diseases at different levels, such as genomics, epigenomics, and transcriptomics. …”
Publicado 2019
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29956por de Rink, Rieks, Klok, Johannes B.M., van Heeringen, Gijs J., Sorokin, Dimitry Y., ter Heijne, Annemiek, Zeijlmaker, Remco, Mos, Yvonne M., de Wilde, Vinnie, Keesman, Karel J., Buisman, Cees J.N.“…[Image: see text] In the biotechnological desulfurization process under haloalkaline conditions, dihydrogen sulfide (H(2)S) is removed from sour gas and oxidized to elemental sulfur (S(8)) by sulfide-oxidizing bacteria. …”
Publicado 2019
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29957por Ragupathy, Subramanyam, Faller, Adam C., Shanmughanandhan, Dhivya, Kesanakurti, Prasad, Shaanker, R. Uma, Ravikanth, Gudasalamani, Sathishkumar, Ramalingam, Mathivanan, Narayanasamy, Song, Jingyuan, Han, Jianping, Newmaster, Steven“…The success of attaining a positive DNA test result along a gradient of industrial processing was compared among four biotechnologies: DNA barcoding, NGS, Sanger sequencing and qPCR. …”
Publicado 2019
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29958por Petrella, Valeria, Aceto, Serena, Colonna, Vincenza, Saccone, Giuseppe, Sanges, Remo, Polanska, Nikola, Volf, Petr, Gradoni, Luigi, Bongiorno, Gioia, Salvemini, Marco“…Furthermore, the sex determination genes identified in our work also provide the opportunity of future biotechnological applications to control natural population of sand flies, reducing their impact on public health. …”
Publicado 2019
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29959por Chiabai, Maria José, Almeida, Juliana Franco, de Azevedo, Mariana Gabriela Dantas, Fernandes, Suelen Soares, Pereira, Vanessa Bastos, de Castro, Raffael Júnio Araújo, Jerônimo, Márcio Sousa, Sousa, Isabel Garcia, de Souza Vianna, Leonora Maciel, Miyoshi, Anderson, Bocca, Anamelia Lorenzetti, Maranhão, Andrea Queiroz, Brigido, Marcelo Macedo“…CONCLUSION: These results provide evidence for the use of this alternative system for delivering therapeutic biopharmaceuticals in loco for treating inflammatory bowel disease, paving the way for a novel low-cost and site-specific biotechnological route for the treatment of inflammatory disorders. …”
Publicado 2019
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29960por de Souza Vandenberghe, Luciana Porto, Garcia, Lina Marcela Blandon, Rodrigues, Cristine, Camara, Marcela Cândido, de Melo Pereira, Gilberto Vinícius, de Oliveira, Juliana, Soccol, Carlos Ricardo“…As an important way to understand not only the ecological role of PPM and their interaction with plants but also the biotechnological application of these cultures to crop management, two main approaches are elucidated: the culture-dependent approach where the microorganisms contained in the plant material are isolated by culturing and are identified by a combination of phenotypic and molecular methods; and the culture-independent approach where microorganisms are detected without cultivating them, based on extraction and analyses of DNA. …”
Publicado 2017
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