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30881“…Pharmaceutical and biotechnological medicines are designed to cure, prevent or treat diseases; however, there are also risks particularly adverse drug reactions (ADRs) can cause serious harm to patients. …”
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30882por Dupuis, Maria L., Fiori, Valentina, Soriani, Alessandra, Ricci, Biancamaria, Dominici, Sabrina, Moricoli, Diego, Ascione, Alessandro, Santoni, Angela, Magnani, Mauro, Cianfriglia, Maurizio“…Taken together, our results suggest that the fully human antibody fragment DIATHIS1 originated by biopanning approach from a phage antibody library may represent a relevant biotechnological platform to design and develop completely human antimelanoma therapeutics of biological origin.…”
Publicado 2015
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30883por Kuuskeri, Jaana, Mäkelä, Miia R., Isotalo, Jarkko, Oksanen, Ilona, Lundell, Taina“…BACKGROUND: The fungal genus Phlebia consists of a number of species that are significant in wood decay. Biotechnological potential of a few species for enzyme production and degradation of lignin and pollutants has been previously studied, when most of the species of this genus are unknown. …”
Publicado 2015
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30884por Sáez-Jiménez, Verónica, Fernández-Fueyo, Elena, Medrano, Francisco Javier, Romero, Antonio, Martínez, Angel T., Ruiz-Dueñas, Francisco J.“…Versatile peroxidase (VP) from the white-rot fungus Pleurotus eryngii is a high redox potential peroxidase of biotechnological interest able to oxidize a wide range of recalcitrant substrates including lignin, phenolic and non-phenolic aromatic compounds and dyes. …”
Publicado 2015
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30885“…Both traits are thus of interest for basic research as well as for biotechnological applications but they typically occur simultaneously thus lowering the respective yields. …”
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30886“…Response surface methodology (RSM) has been widely used for the optimization and studying of different parameters in biotechnological processes. OBJECTIVES: In this study, the expression of synthetic appA gene in P. pastoris was greatly improved by adjusting the expression condition. …”
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30887por Gao, Xiaolong, Hu, Xiangyun, Tong, Lina, Liu, Dandan, Chang, Xudong, Wang, Haixin, Dang, Ruyi, Wang, Xinglong, Xiao, Sa, Du, Enqi, Yang, Zengqi“…The comparatively small size, high affinity, high solubility, low immunogenicity and ability to bind epitopes inaccessible to conventional antibodies of VHH make them ideal candidates for a considerable number of therapeutic and biotechnological applications. However, an anti-NDV VHH has not been reported to date. …”
Publicado 2016
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30888por Lee, Yong-Suk“…These biochemical properties, sequence identity, and phylogenetic analysis suggest that MtEst45 represents a novel and valuable bacterial lipolytic enzyme family and is useful for biotechnological applications.…”
Publicado 2016
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30889“…Finally, while C. reinhardtii was traditionally used as a model organism for the development of transformation systems and their subsequent improvement, similar technologies can be adapted for other microalgae that may have higher biotechnological value.…”
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30890Cloning, expression and characterization of a β-d-xylosidase from Lactobacillus rossiae DSM 15814(T)por Pontonio, Erica, Mahony, Jennifer, Di Cagno, Raffaella, O’Connell Motherway, Mary, Lugli, Gabriele Andrea, O’Callaghan, Amy, De Angelis, Maria, Ventura, Marco, Gobbetti, Marco, van Sinderen, Douwe“…Xylanase cocktails are used on an industrial scale for biotechnological purposes. Lactobacillus rossiae DSM 15814(T) can utilize an extensive set of carbon sources, an ability that is likely to contribute to its adaptive ability. …”
Publicado 2016
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30891por Ibarra-Arellano, Miguel A., Campos-González, Adrián I., Treviño-Quintanilla, Luis G., Tauch, Andreas, Freyre-González, Julio A.“…Abasy (Across-bacteria systems) Atlas provides a comprehensive inventory of annotated functional systems, global network properties and systems-level elements (global regulators, modular genes shaping functional systems, basal machinery genes and intermodular genes) predicted by the natural decomposition approach for reconstructed and meta-curated regulatory networks across a large range of bacteria, including pathogenically and biotechnologically relevant organisms. The meta-curation of regulatory datasets provides the most complete and reliable set of regulatory interactions currently available, which can even be projected into subsets by considering the force or weight of evidence supporting them or the systems that they belong to. …”
Publicado 2016
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30892por Falasca, Francesca, Russo, Cinzia Dello, Mora, Barbara, Pirazzoli, Antonella, Fantauzzi, Alessandra, Navarra, Pierluigi, Pizzuti, Antonio, De Vito, Corrado, Antonelli, Guido, Turriziani, Ombretta“…To date, four different commercial assays based on the real-time quantitative polymerase chain reaction (Q-PCR) technique are available for the detection of HLA-B*57:01: Duplicα-RealTime Reagent Set HLA-B*57:01 by Euroclone, HLA-B*57:01 Real-TM by Sacace Biotechnologies, COBAS AmpliPrep/COBAS TaqMan HLA-B*57:01 Screening Test by Roche Diagnostic, and HLA-B*57:01 by Nuclear Laser Medicine. …”
Publicado 2016
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30893“…Identification of such novel petrochemical hydrocarbon degrading electricigens, not only expands the knowledge on the range of bacteria known for the hydrocarbon bioremediation but also shows a biotechnological potential that goes well beyond its applications to MERS.…”
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30894por Romão-Dumaresq, Aline Silva, Dourado, Manuella Nóbrega, Fávaro, Léia Cecilia de Lima, Mendes, Rodrigo, Ferreira, Anderson, Araújo, Welington Luiz“…Plant-associated fungi are considered a vast source for biotechnological processes whose potential has been poorly explored. …”
Publicado 2016
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30895por Wanka, Franziska, Arentshorst, Mark, Cairns, Timothy C., Jørgensen, Thomas, Ram, Arthur F. J., Meyer, Vera“…In order to assess whether these promoters were suitable to produce heterologous proteins during retentostat cultivation, the secreted antifungal protein (AFP) from Aspergillus giganteus, which has many potential biotechnological applications, was expressed in A. niger during retentostat cultivation. …”
Publicado 2016
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30896“…Microorganism that had been discovered in natural DCXC will provide sources for screening the new bioactive metabolites and its biotechnological application. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12866-016-0813-5) contains supplementary material, which is available to authorized users.…”
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30897por Mejía-Caballero, Alejandra, de Anda, Ramón, Hernández-Chávez, Georgina, Rogg, Simone, Martinez, Alfredo, Bolívar, Francisco, Castaño, Victor M., Gosset, Guillermo“…These polymers have current and potential applications in the chemical, medical, electronics and materials industries. The biotechnological production of melanins offers the possibility of obtaining these pigments in pure form and relatively low cost. …”
Publicado 2016
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30898por Weimann, Aaron, Mooren, Kyra, Frank, Jeremy, Pope, Phillip B., Bremges, Andreas, McHardy, Alice C.“…Bacterial communities can also aid in biotechnological processes such as wastewater treatment or decontamination of polluted soils. …”
Publicado 2016
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30899“…BACKGROUND: Glycerol is an abundant by-product of biodiesel production and has several advantages as a substrate in biotechnological applications. Unfortunately, the popular production host Saccharomyces cerevisiae can barely metabolize glycerol by nature. …”
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30900por Netala, Vasudeva Reddy, Kotakadi, Venkata Subbaiah, Gaddam, Susmila Aparna, Ghosh, Sukhendu Bikash, Tartte, Vijaya“…The enhancement of plant secondary metabolite production in cell suspension cultures through biotic or abiotic elicitation has become a potential biotechnological approach for commercialization or large-scale production of bioactive compounds. …”
Publicado 2016
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