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30921por Odinot, Elise, Fine, Frédéric, Sigoillot, Jean-Claude, Navarro, David, Laguna, Oscar, Bisotto, Alexandra, Peyronnet, Corinne, Ginies, Christian, Lecomte, Jérôme, Faulds, Craig B., Lomascolo, Anne“…Rapeseed meal is a cheap and abundant raw material, particularly rich in phenolic compounds of biotechnological interest. In this study, we developed a two-step bioconversion process of naturally occurring sinapic acid (4-hydroxy-3,5-dimethoxycinnamic acid) from rapeseed meal into canolol by combining the complementary potentialities of two filamentous fungi, the micromycete Aspergillus niger and the basidiomycete Neolentinus lepideus. …”
Publicado 2017
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30922por de Oliveira, Tássio Brito, Gostinčar, Cene, Gunde-Cimerman, Nina, Rodrigues, Andre“…Peptidases from thermophilic fungi have adaptations to high temperature that makes them adequate for biotechnological application. In the present study, we profiled the genomes of heat-tolerant fungi and phylogenetically related mesophilic species for genes encoding for peptidases and their putative adaptations for thermostability. …”
Publicado 2018
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30923“…Due to its enhancing effect on cellulase activity, HAX1 was shown to be not only interesting for basic research, but also a promising candidate for expanding the set of biotechnological tools for industrial application of T. reesei. …”
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30924por Ma, Zhi-Ping, Song, Yu, Cai, Zhong-Hua, Lin, Zhi-Jun, Lin, Guang-Hui, Wang, Yan, Zhou, Jin“…This study indicates that coral microbes are a resource bank for developing QS inhibitors and they will facilitate the discovery of new biotechnologically relevant compounds that could be used instead of traditional antibiotics.…”
Publicado 2018
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30925por Wang, Yanan, Zhang, Sufang, Zhu, Zhiwei, Shen, Hongwei, Lin, Xinping, Jin, Xiang, Jiao, Xiang, Zhao, Zongbao Kent“…BACKGROUND: Lipid accumulation by oleaginous microorganisms is of great scientific interest and biotechnological potential. While nitrogen limitation has been routinely employed, low-cost raw materials usually contain rich nitrogenous components, thus preventing from efficient lipid production. …”
Publicado 2018
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30926por Kotogán, Alexandra, Zambrano, Carolina, Kecskeméti, Anita, Varga, Mónika, Szekeres, András, Papp, Tamás, Vágvölgyi, Csaba, Takó, Miklós“…However, considering that most commercial lipases are derived from filamentous fungal sources, their investigation can contribute to the cost-effective development of new biotechnological processes. Here, an extracellular lipase with a molecular mass of 30 kDa was isolated from Mortierella echinosphaera CBS 575.75 and characterized. …”
Publicado 2018
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30927“…Besides (growth and synthesis) rates, metabolic yields are key parameters for the characterization of biochemical transformation processes, especially in the context of biotechnological applications. However, yields are ratios of rates, and hence the optimization of yields (as nonlinear objective functions) under arbitrary linear constraints is not possible with current flux-balance analysis techniques. …”
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30928por Noriler, Sandriele A., Savi, Daiani C., Aluizio, Rodrigo, Palácio-Cortes, Angela M., Possiede, Yvelise M., Glienke, Chirlei“…These data suggested that both, the plant species and plant tissues play a role in the composition of endophytic community. As regards the biotechnological potential, 5 isolates showed activity against the phytopathogens Phyllosticta citricarpa, Colletotrichum abscissum, and Fusarium verticilioides, and 8 isolates showed high activity against clinical pathogens and were selected for the production of crude extract in different culture media. …”
Publicado 2018
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30929“…Triggering expression of these “silent” clusters could result in unlocking the chemical diversity they control, allowing the discovery of novel molecules of both medical and biotechnological interest. Therefore, both genetic and cultivation-based techniques have been developed aimed at stimulating expression of these “silent” genes. …”
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30930“…CONCLUSION: The analysis confirmed the camel rumen’s microbiome as a dense and yet largely untapped source of enzymes with the potential to be used in a range of biotechnological processes including biofuel, fine chemicals and food processing industries. …”
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30931“…Our results indicate that heterotrophic organisms like E. coli hold a possibly underestimated potential for CO(2) assimilation which may complement existing biotechnological approaches for capturing CO(2). Furthermore, we envision that the developed OptMDFpathway approach can be used for many other applications within the framework of constrained-based modeling and for rational design of metabolic networks.…”
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30932por Charest-Morin, Xavier, Hébert, Jacques, Rivard, Georges-Étienne, Bonnefoy, Arnaud, Wagner, Eric, Marceau, François“…Tissue plasminogen activator (tPA) slowly (≥1 h) induced iBK generation in control blood, but more rapidly and intensely so in that of HAE patients. Effects of biotechnological inhibitors indicate that tPA recruits factor XIIa (FXIIa) and plasma kallikrein to generate iBK. …”
Publicado 2018
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30933por Garrigues, Sandra, Gandía, Mónica, Castillo, Laia, Coca, María, Marx, Florentine, Marcos, Jose F., Manzanares, Paloma“…In this work, the production of the putative AFPs from P. expansum was evaluated, but only the representative of class A, PeAfpA, was identified in culture supernatants of the native fungus. The biotechnological production of PeAfpB and PeAfpC was achieved in Penicillium chrysogenum with the P. chrysogenum-based expression cassette, which had been proved to work efficiently for the production of other related AFPs in filamentous fungi. …”
Publicado 2018
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30934por Brito, Thais L., Campos, Amanda B., Bastiaan von Meijenfeldt, F. A., Daniel, Julio P., Ribeiro, Gabriella B., Silva, Genivaldo G. Z., Wilke, Diego V., de Moraes, Daniela T., Dutilh, Bas E., Meirelles, Pedro M., Trindade-Silva, Amaro E.“…Results presented here add to the growing characterization of shipworm symbiotic microbiomes and indicate that the N. reynei gill gammaproteobacterial community is a prolific source of biotechnologically relevant enzymes for wood-digestion and bioactive compounds production.…”
Publicado 2018
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30935por Fhoula, Imene, Rehaiem, Amel, Najjari, Afef, Usai, Donatella, Boudabous, Abdellatif, Sechi, Leonardo Antonio, Hadda-Imene, Ouzari“…Further studies may reveal their potential and possible biotechnological and probiotic applications.…”
Publicado 2018
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30936“…Overall, the redox features of PpcF suggest that biotechnological applications of G. metallireducens may require less negative working functional redox windows than those using by G. sulfurreducens.…”
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30937“…They open up new avenues of interrogating this process in other species and provide possible routes to their biotechnological applications, including in metal recovery, biomaterials production, and synthetic community engineering.…”
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30938por Ulloa, Ricardo, Moya-Beltrán, Ana, Rojas-Villalobos, Camila, Nuñez, Harold, Chiacchiarini, Patricia, Donati, Edgardo, Giaveno, Alejandra, Quatrini, Raquel“…This has been harnessed in biotechnologies such as biomining, where microorganisms facilitate the recovery of economically important metals such as gold. …”
Publicado 2019
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30939por Koch, Sabine, Kohrs, Fabian, Lahmann, Patrick, Bissinger, Thomas, Wendschuh, Stefan, Benndorf, Dirk, Reichl, Udo, Klamt, Steffen“…Constraint-based modeling (CBM) is increasingly used to analyze the metabolism of complex microbial communities involved in ecology, biomedicine, and various biotechnological processes. While CBM is an established framework for studying the metabolism of single species with linear stoichiometric models, CBM of communities with balanced growth is more complicated, not only due to the larger size of the multi-species metabolic network but also because of the bilinear nature of the resulting community models. …”
Publicado 2019
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30940por Arrillaga, Isabel, Morcillo, Marian, Zanón, Israel, Lario, Francisco, Segura, Juan, Sales, Ester“…Somatic embryogenesis (SE) has been so far, the preferred biotechnological strategy for maritime pine breeding programs initiated at the middle-end of the 20th century. …”
Publicado 2019
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