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31041“…Our findings contribute to understanding fungal diversity in China and provide a basis for future studies exploring the ecological roles and biotechnological potential of these fungi. Additionally, our multi-gene phylogenetic approach provides increased accuracy and resolution in the delimitation of species boundaries within Phaeosphaeriaceae. …”
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31042“…While biosafety should be a central feature of emerging biotechnologies to minimize unintended consequences, few studies quantitatively evaluate the risk of off-target mutations. …”
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31043“…Application of recent biotechnological advancements, including single cell RNA sequencing and complex data analysis methods has begun to explain the shifting inflammatory signaling, variation in cellular subpopulations, differential gene expression, mechanical loading, and metabolic stresses which contribute to age and stress related degeneration of the IVD. …”
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31044por Giraldo, Lina Dávila R., Baez, Paula Villanueva X., Forero, Cristian Zambrano J., Arango, Walter Murillo“…Submerged cultivation is an industrially implemented biotechnological technique used to produce a wide variety of fungal metabolites, which are of economic and social importance due to their food, pharmaceutical, and agronomic applications. …”
Publicado 2023
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31045“…Knowledge of the protein sorting rules will be crucial for the biotechnological re-engineering of cyanobacterial cells, and for understanding the evolutionary development of the thylakoids. …”
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31046por Yao, Roseline Assiah, Reyre, Jean-Lou, Tamburrini, Ketty C., Haon, Mireille, Tranquet, Olivier, Nalubothula, Akshay, Mukherjee, Saumashish, Le Gall, Sophie, Grisel, Sacha, Longhi, Sonia, Madhuprakash, Jogi, Bissaro, Bastien, Berrin, Jean-Guy“…IMPORTANCE: Lytic polysaccharide monooxygenases (LPMOs) have been mainly studied in a biotechnological context for the efficient degradation of recalcitrant polysaccharides. …”
Publicado 2023
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31047por Binet, Thomas, Padiolleau-Lefèvre, Séverine, Octave, Stéphane, Avalle, Bérangère, Maffucci, Irene“…BACKGROUND: Single-stranded nucleic acids (ssNAs) have important biological roles and a high biotechnological potential linked to their ability to bind to numerous molecular targets. …”
Publicado 2023
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31048por Li, Jincheng, Liu, Sen, Yang, Chenjie, Keyhani, Nemat O., Pu, Huili, Lin, Longbin, Li, Xiaoxia, Jia, Peisong, Wu, Dongmei, Pan, Jieming, Stevenson, Philip C., Fernández-Grandon, G Mandela, Zhang, Liaoyuan, Chen, Yuxi, Guan, Xiayu, Qiu, Junzhi“…Amylases are secreted by many plant pathogenic fungi to access host nutrients through the metabolism of starch, and the identification of new amylases can have important biotechnological applications. Production of amylase by A. apis in submerged culture was optimized using the response surface method (RSM). …”
Publicado 2023
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31049“…Finally, the possibility of separating aggregate fractions with different complexities offers new options for biotechnological strategies aimed at improving the yield of folded and active recombinant proteins.…”
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31050“…BACKGROUND: The preservation of fish egg quality after ovulation-control protocols is a major issue for the development of specific biotechnological processes (e.g. nuclear transfer). Depending on the species, it is often necessary to control the timing of ovulation or induce the ovulatory process. …”
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31051“…These features make the gspE mutant an improved host with a remarkable biotechnological potential in recombinant protein secretion at low temperature. …”
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31052por Clarke, Donna, Jablonski, Sophie, Moran, Brighid, Anandarajah, Gabrial, Taylor, Gail“…Due to the number and complexity of bioenergy pathways and technologies in the model, three chains and two underpinning technologies were selected for detailed investigation: (1) lignocellulosic hydrolysis for the production of bioethanol, (2) gasification technologies for heat and power, (3) fast pyrolysis of biomass for bio-oil production, (4) biotechnological advances for second generation bioenergy crops, and (5) the development of agro-machinery for growing and harvesting bioenergy crops. …”
Publicado 2009
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31053por Noad, Rob J, Stewart, Meredith, Boyce, Mark, Celma, Cristina C, Willison, Keith R, Roy, Polly“…These loci were used to allow the recovery two recombinant virus-like particles with potential biotechnological applications (influenza A virus HA/M1 particles and bluetongue virus VP2/VP3/VP5/VP7 particles) and the mammalian chaperone and cancer drug target CCT (16 subunits formed from 8 proteins). …”
Publicado 2009
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31054“…Therefore, detailed studies at the resolution of cell type are of great relevance in order to accurately describe the process and to identify potential candidate genes for biotechnological applications. RESULTS: Efficient protocols for the isolation of specific citrus cell types, namely laminar abscission zone (LAZ) and petiolar cortical (Pet) cells based on laser capture microdissection (LCM) and for RNA microextraction and amplification have been developed. …”
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31055“…BACKGROUND: Protein-protein interactions are fundamental for the majority of cellular processes and their study is of enormous biotechnological and therapeutic interest. In recent years, a variety of computational approaches to the protein-protein docking problem have been reported, with encouraging results. …”
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31056por Funke, Matthias, Buchenauer, Andreas, Mokwa, Wilfried, Kluge, Stefanie, Hein, Lea, Müller, Carsten, Kensy, Frank, Büchs, Jochen“…BACKGROUND: The efficiency of biotechnological production processes depends on selecting the best performing microbial strain and the optimal cultivation conditions. …”
Publicado 2010
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31057por Jeon, Se Jin, Seo, Jung Eun, Yang, Sung-Il, Choi, Ji Woong, Wells, David, Shin, Chan Young, Ko, Kwang Ho“…After we transiently modulated FMRP expression (silencing or enhancing) by using molecular biotechnological methods such as small hairpin RNA virus-induced knock down and overexpression using transfection with FMRP expression vectors, cellular viability was measured using propidium iodide staining, TUNEL staining, and FACS analysis along with the level of activation of PI3K-Akt pathway by Western blot. …”
Publicado 2011
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31058“…BACKGROUND: The rational design of modified proteins with controlled stability is of extreme importance in a whole range of applications, notably in the biotechnological and environmental areas, where proteins are used for their catalytic or other functional activities. …”
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31059“…BACKGROUND: Many filamentous fungal genomes contain complex groups of multicopper oxidase (MCO) coding genes that makes them a good source for new laccases with potential biotechnological interest. A bioinformatics analysis of the Aspergillus niger ATCC 1015 genome resulted in the identification of thirteen MCO genes. …”
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31060por Ramli, Aizi Nor Mazila, Mahadi, Nor Muhammad, Rabu, Amir, Murad, Abdul Munir Abdul, Bakar, Farah Diba Abu, Illias, Rosli Md“…CONCLUSION: By taking advantage of its high activity at low temperatures and its acidic pH optimum, this recombinant chitinase will be valuable in various biotechnological applications under low temperature and acidic pH conditions.…”
Publicado 2011
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