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541“…The present article explores the possible existence of a true 'class effect' for agents available for the treatment of bipolar disorder. METHODS: We reviewed the available treatment data from randomized controlled trials (RCTs) and explored 16 'agent class'/'treatment issue' cases for bipolar disorder. …”
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542“…We report the perioperative mortality and morbidity of cementless bipolar hemiarthroplasty in a series of mobile elderly patients (age >70 years) with femoral neck fractures. …”
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543“…BACKGROUND: Bipolar Disorder (BD) is a chronic, recurrent and highly prevalent illness. …”
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544“…We did not find a significant reduction in the total expression of RELN in schizophrenia or bipolar disorder. However, we did find a significant reduction of the proportion of the short RELN isoform, missing the C-terminal region in bipolar disorder, and imbalance in the allelic expression of RELN in schizophrenia. …”
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545por Goes, Fernando S., Rongione, Michael, Chen, Yun-Ching, Karchin, Rachel, Elhaik, Eran, Potash, James B.“…The Neuregulin-ErbB4 pathway plays a crucial role in brain development and constitutes one of the most biologically plausible signaling pathways implicated in schizophrenia and, to a lesser extent, in bipolar disorder (BP). However, recent genome-wide association analyses have not provided evidence for common variation in NRG1 or ERBB4 influencing schizophrenia or bipolar disorder susceptibility. …”
Publicado 2011
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546por Zappitelli, Marcelo C, Bordin, Isabel A, Hatch, John P, Caetano, Sheila C, Zunta-Soares, Giovana, Olvera, Rene L, Soares, Jair C“…BACKGROUND: Recent studies have demonstrated high rates of psychopathology in the offspring of parents with bipolar disorder. The aim of this study was to identify psychiatric diagnoses in a sample of children of bipolar parents. …”
Publicado 2011
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547“…To date, the Dandy-Walker syndrome has not been described in association with bipolar disorder type I mania, and therefore we briefly report the case of a Dandy-Walker variant associated with acute mania. …”
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548por Koefoed, Pernille, Andreassen, Ole A., Bennike, Bente, Dam, Henrik, Djurovic, Srdjan, Hansen, Thomas, Jorgensen, Martin Balslev, Kessing, Lars Vedel, Melle, Ingrid, Møller, Gert Lykke, Mors, Ole, Werge, Thomas, Mellerup, Erling“…Permutation tests indicated that some of these combinations might be related to bipolar disorder. The WTCCC bipolar dataset were use for replication, 469 of the 803 SNP were present in the WTCCC dataset either directly (n = 132) or by imputation (n = 337) covering 51 of our selected genes. …”
Publicado 2011
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549“…Lithium, the first line of therapy for bipolar disorder, inhibits GSK-3, activates Wnt signaling and stimulates adult neurogenesis, which may be important for its therapeutic effects. …”
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550“…Bipolar affective disorder is a disabling illness with substantial morbidity and many management challenges. …”
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551por Frangou, Sophia“…Methods: Data presented here are derived from the Vulnerability to Bipolar Disorders Study (VIBES) which includes BD patients, asymptomatic relatives and controls. …”
Publicado 2012
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552“…In a number of investigations, hippocampal neurochemicals were evaluated in the patients with bipolar disorder who were on their first episode or euthymic periods. …”
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553por Reddy, Y.C. JanardhanEnlace del recurso
Publicado 2012
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554“…BACKGROUND: Bipolar disorder (BD) is a chronic, relapsing, episodic mental illness associated with other psychiatric comorbidities. …”
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555por Waszkiewicz, Napoleon, Zalewska-Szajda, Beata, Szajda, Sławomir Dariusz, Simonienko, Katarzyna, Zalewska, Anna, Szulc, Agata, Ładny, Jerzy Robert, Zwierz, Krzysztof“…In patients with a family history for bipolar disorder the use of even minimal dose of sibutramine should be contraindicated.…”
Publicado 2012
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556“…To test the feasibility of the concept, a prototype system was devised, which was followed by trials including four healthy volunteers as well as a bipolar patient. RESULTS: The sensors utilised in the study yielded behavioural data which may be of significant use in detecting early effects of a bipolar episode. …”
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557por Mellerup, Erling, Andreassen, Ole, Bennike, Bente, Dam, Henrik, Durovic, Srdjan, Hansen, Thomas, Melle, Ingrid, Møller, Gert Lykke, Mors, Ole, Koefoed, Pernille“…In a previous study of patients with bipolar disorder and controls combinations of SNP genotypes were analyzed, and four large clusters of combinations were found to be significantly associated with bipolar disorder. …”
Publicado 2012
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558por Raviraj, AEnlace del recurso
Publicado 2012
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559“…In this study, we validated the Inventory of Stigmatizing Experiences (ISE) as a tool to help quantify the stigma experienced by patients with bipolar disorder and its impact on their lives. The ISE has two components, ie, the Stigma Experiences Scale (SES) and the Stigma Impact Scale (SIS), which were administered to a population of Argentinean patients with bipolar disorder. …”
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560“…Bipolar affective disorder is a serious mental disease associated with significant morbidity and mortality. …”
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