“…BACKGROUND: DExD-box helicase 21 (DDX21) is an essential member of the RNA helicase family. …”
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“…Both the reconfigurable cipher unit and the reconfigurable hash unit contain a unified data path to implement Data Encryption Standard (DES)/Advanced Encryption Standard (AES)/ShangMi 4 (SM4) and Secure Hash Algorithm-1 (SHA-1)/SHA-256/SM3 algorithms, respectively. A reconfigurable S-Box for AES and SM4 is designed based on the composite field Galois field (GF) GF(((2(2))(2))(2)), which significantly reduces hardware overhead and power consumption compared with the conventional implementation by look-up tables. …”
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“…The elevated cAMP level resulted from increased transcription activity and expression of adenylyl cyclase 1 (AC1) by SHBs through a binary E-box factor binding site (BEF). Taken together, we unveiled a novel pathogenic role and mechanism of SHBs in hepatic gluconeogenesis, and these results might highlight a potential target for preventive and therapeutic intervention in the development and progression of HBV-associated diabetes. …”
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“…Innovative outside-the-box approaches are needed to overcome immunological roadblocks to the success of past and current vaccine regimens. …”
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“…TGFβ signaling-mediated downregulation of NLE1 was prevented by ectopic expression of c-MYC, which occupied an E-box–containing region within the NLE1 promoter. …”
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“…In addition, FKA also downregulated the catabolic enzyme expression, i.e., aggrecanase-2 (ADAMTS5) and matrix metalloproteinases (MMPs), and helped in the upregulation of the anabolic protein expression, i.e., type II collagen (Col2), Aggrecan, and sry-box transcription factor 9 (SOX9). Moreover, FKA ameliorated IL-1β-triggered autophagy in chondrocytes, and it was observed that the FKA causes anti-inflammatory effects by the mitogen-activated protein kinase (MAPK) and phosphoinositide-3-kinase/Akt/mammalian target of rapamycin (PI3K/AKT/mTOR) signaling pathways inhibition. …”
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“…GO annotations and KEGG pathway enrichments of the DEGs based on RNA-seq data indicated that DEGs were involved in (1) ion and membrane homeostasis, including ABC transporter, CLC, NCX, and NHX; (2) Ca(2+) sensing and transduction, including BK channel, EF-hand domain, and calmodulin binding protein; (3) phytohormone signaling and regulation, including TPR, FBP, LRR, and PP2C; (4) transcription factors, including zinc finger proteins, YABBY, and SBP-box; (5) antioxidation process, including GST, PYROX, and ALDH; (6) post-translational modification, including UCH, ubiquitin family, GT, MT and SOT. …”
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“…The EMT phenotype was assessed with the E-cadherin, CD44, and zinc finger E-box binding homeobox 1 (ZEB-1) immunohistochemical markers. …”
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“…Next, a non-Intersection over Union bounding box selection and suppression algorithm, the confluence strategy, is used. …”
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“…The exercises used were clean-and-press, box jump, TRX chest press, wall ball throws, burpees, repeated 10 m sprints, sumo squat-and-upright row, and abdominal crunches. …”
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“…Group A had 2 bone tunnels and 4 sutures using an X-box configuration, and group B had a suture bridge construct of 4 anchors. …”
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“…However, the molecular mechanism of tyrosine kinase binding protein (TYROBP) and sex-determining region Y Box-6 (SOX6) in the ccRCC was not precise. METHODS: Bioinformatics analysis was performed to explore the hub role of TYROBP and SOX6 on the ccRCC. …”
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“…Aberrant crosstalk between pulmonary vascular endothelial cells (PVECs) and pulmonary arterial smooth muscle cells (PASMCs) that is mediated by exosomes plays an essential role in the progression of PH. FoxM1 (Forkhead box M1) is a key transcription factor that governs many important biological processes. …”
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“…Diagnostic workups included a complete medical history, physical and neurological examinations, neuropsychological testing, the Clinical Dementia Rating Scale‐Sum of Boxes (CDR‐SOB), Montreal Cognitive Assessment (MoCA), blood tests and brain imaging, preferably with magnetic resonance imaging. …”
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“…Furthermore, the protein expression levels of EEC biomarkers, such as estrogen receptor (ER), progesterone receptor (PR), paired box 2 (PAX2), PTEN and p53 were assessed using immunohistochemistry. …”
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“…Rat BMSCs pretreated with the euchromatic histone lysine methyltransferase 2 (G9a) inhibitor BIX01294 were transfected with a T-box 18 overexpression plasmid to induce BMSCs to form pacemaker-like cells. …”
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“…We analyzed the role of the Deep Learning technique using a single variable size bounding box (SVB) option and employed a Voxel Based (VB) NET CNN model. …”
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“…The presented IPHPDT dataset contains four types of human postures, consisting of 75,000 images well-annotated with axis-aligned bounding boxes and postures of the persons. Based on this well-annotated IPHPDT dataset and three state-of-the-art algorithms, i.e., YOLOF (short for You Only Look One-level Feature), YOLOX (short for Exceeding YOLO Series in 2021) and TOOD (short for Task-aligned One-stage Object Detection), we establish three baseline detectors, called IPH-YOLOF, IPH-YOLOX, and IPH-TOOD. …”
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“…Of particular interest is the IKKβ-catalyzed phosphorylation of IκBα residues Ser(32) and Ser(36) within a conserved destruction box motif. To investigate the catalytic mechanism of IKKβ, we performed pre–steady-state kinetic analysis of the phosphorylation of IκBα protein substrates catalyzed by constitutively active, human IKKβ. …”
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“…The present study aimed to detect the expression of deoxyribonuclease 1-like 3 (DNASE1L3) and forkhead-box P2 (FOXP2) in LUAD cells to investigate the role of DNASE1L3 in the regulation of proliferation, migration, invasion and tube formation of LUAD cells and how FOXP2 affects DNASE1L3 expression. …”
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