“…Furthermore, decreased mammalian target of rapamycin and increased Forkhead box protein 1 expression was significantly restored by combined supplementation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Loss of function of the tumor suppressor F-box WD-40 domain containing 7 (FBW7) mutations leads to the accumulation of its substrate MCL-1 which is associated with Taxol resistance in human cancers. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the light of this, morphometric analyses (k-means, MANOVA, PCA, DA, and Box-Plot) have been carried out on the Sardinian and Venetian populations to verify if this distinction is detectable also by a morphological point of view. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…First, Mask RCNN was improved by fusing the attention mechanism into the ResNeXt, modifying the anchor box parameters, and adding a tiny fully connected layer branch into the mask branch to realize the detection and rough segmentation of the tapped area. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…To compare the range and distribution of the average age at onset of kidney failure by race/ethnicity and sex, we used box plots and confidence intervals. Multivariable logistic regression was used to estimate OR for kidney transplant. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Recently, commercial grade technologies have provided black box algorithms potentially relating to musculoskeletal injury (MSKI) risk and functional movement deficits, in which may add value to a high-performance model. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…IP3 regulated the Forkhead box O3 (FOXO3)/Cyclin D1 (CCND1) signaling pathway. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Besides, the transcript factor forkhead box protein O1 (FOXO1) could suppress the CRC cell growth. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…However, many developed frameworks effectively function as black boxes, granting minimal context to the decision-making process. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The structure of AtAkαGal3 comprises three domains: an N-terminal domain with 13 antiparallel β-strands, a catalytic domain with an (α/β)(8)-barrel fold and a C-terminal domain composed of β-sheets that form two Greek-key motifs. The WW box of the N-terminal domain, which comprises the conserved residues FRSK(75)XW(77)W(78) in the RFO synthases, contributes Trp77 and Trp78 to the +1 subsite to contribute to the substrate-binding ability together with the (α/β)(8) barrel of the catalytic domain. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We found a significant decrease of DExH-Box Helicase 34 (DHX34), suppressor with morphogenetic effect on genitalia 5 (SMG5), and SMG7 expression at 6 h post-infection, followed by a significant increase of these genes and also UPF1 and UPF2 at 9 h post-infection. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Background This study aimed to investigate the effects of serum high mobility group box-1 (HMGB1), interleukin (IL)-6, IL-8, IL-1β, IL-10, and tumor necrosis factor alpha (TNF-α) levels on disease severity and mortality in Crimean-Congo hemorrhagic fever (CCHF) patients. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The animals were tested for learning and memory the next day, by the shuttle box. The time that a rat took to enter the dark part was considered as memory. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Using AIDmut-Seq for the major quorum sensing regulator LasR in Pseudomonas aeruginosa, we confirmed that a few TF-guided C-T (or G-A) conversions occurred near their binding boxes on the genome, and a number of previously characterized and uncharacterized LasR-binding sites were detected. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This has been shown in several species; however, the situation in ruminants remains a black box. Here, we aimed to elucidate the relationship between the hindgut microbiota, metabolism, and reproductive hormones in domestic goats (Capra hircus) during nonpregnancy, pregnancy, and lactation stages. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Relative mRNA expression of Ca (2+)-independent phospholipases A2 beta (iPLA 2β), P53, Zinc finger E-box binding homeobox 1 (ZEB1) and GSH-dependent peroxidase 4 (GPX4) were evaluated. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The purpose of this study is to compare the antidepressant effects of traxoprodil in different doses and different durations of administration and to explore whether traxoprodil exerts antidepressant effects via the brain-derived neurotrophic factor/extracellular signal-regulated kinase/cAMP-response element binding protein (BDNF/ERK/CREB) and protein kinase B/Forkhead box O/building information modelling (AKT/FOXO/Bim) signaling pathway. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Real-time RT-PCR analysis revealed a deceased expression of miR-181b-2-3p and an increased expression of its target SRY-related high-mobility group box transcription factor 21 (SOX21) in a dose- and time-dependent fashion. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Erythromycin-loaded transethosomes (EM-TE) were generated and optimized using a Box–Behnken design employing, phospholipid concentration (A), surfactant concentration (B), and ethanol content (C) as independent variables. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In neuronal cells, plasma, and brain tissue, curcumin and the low-expressed lncRNA GAS5 can inhibit the expression of IL-1β (interleukin 1 beta), TNF-α (tumor necrosis factor alpha), IL-6 (interleukin 6), Sox2 (SRY-box transcription factor 2), Nanog, and Oct4 (octamer-binding transcription factor 4). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso