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27961por Sharma, Vinay, Gangurde, Sunil S., Nayak, Spurthi N., Gowda, Anjan S., Sukanth, B.S., Mahadevaiah, Supriya S., Manohar, Surendra S., Choudhary, Rakeshkumar S., Anitha, T., Malavalli, Sachin S., Srikanth, S.N., Bajaj, Prasad, Sharma, Shailendra, Varshney, Rajeev K., Latha, Putta, Janila, Pasupuleti, Bhat, Ramesh S., Pandey, Manish K.“…Furthermore, important candidate genes encoding DHHC-type zinc finger family protein (arahy.J0Y6Y5), peptide transporter 1 (arahy.8ZMT0C), pentatricopeptide repeat-containing protein (arahy.4A4JE9), Ulp1 protease family (arahy.X568GS), Kelch repeat F-box protein (arahy.I7X4PC), FRIGIDA-like protein (arahy.0C3V8Z), and post-illumination chlorophyll fluorescence increase (arahy.92ZGJC) were the underlying three QTL clusters. …”
Publicado 2023
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27962por Soltani-Zangbar, Mohammad Sadegh, Hajivalili, Mahsa, Daneshdoust, Danyal, Ghadir, Sara, Savari, Golaleh, Zolfaghari, Mohammadali, Aghebati-Maleki, Leili, Oloufi, Solmaz, Nouri, Narjes, Amini, Naser, Mehdizadeh, Amir, Ghasemi Moghadam, Hossein, Mahmoodpoor, Ata, Ahmadian Heris, Javad, Yousefi, Mehdi“…The RNA was extracted from each sample and after synthesis of c-DNA, the relative expression of miR-155, suppressor of cytokine signaling (SOCS-1), Signal transducer and activator of transcription 3 (STAT3), and Fork Head Box Protein 3 (FoxP3) was evaluated by real-time PCR. …”
Publicado 2023
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27963por Feng, Wen-Qing, Zhang, Yu-Chen, Gao, Han, Li, Wen-Chang, Miao, Yi-Ming, Xu, Zi-Feng, Xu, Zhuo-Qing, Zhao, Jing-Kun, Zheng, Min-Hua, Zong, Ya-Ping, Lu, Ai-Guo“…Forkhead box D1 (FOXD1) serves a critical role in colorectal cancer (CRC). …”
Publicado 2023
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27964“…The transcription factor Forkhead Box M1 may contribute to the increased expression levels of SKP2 in certain tumors. …”
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27965por Ren, Haozhen, Chen, Yuyan, Zhu, Zhengyi, Xia, Jinkun, Liu, Shujun, Hu, Yingzhe, Qin, Xueqian, Zhang, Lu, Ding, Yitao, Xia, Senzhe, Wang, Jinglin“…Th17/Treg cells are a pair of essential components in adaptive immune response in liver IRI, and forkhead box O1 (FOXO1) has the properties of maintaining the function and phenotype of immune cells. …”
Publicado 2023
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27966por Sharma, Sheetal, Roy, Tushar, Kashyap, Yogesh, Buck, Martin, Schumacher, Jorg, Goswami, Dweipayan, Gang, Shraddha, Saraf, Meenu“…The EPS production was studied by applying Box Behnken design (BBD) under drought stress which was artificially induced by using polyethene glycol 6000 under osmotic stress condition 3.65% w/v of EPS dry weight was obtained. …”
Publicado 2023
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27967por Medina-Fraga, Ana L., Chinen, Lucas A., Demkura, Patricia V., Lichy, Micaela Z., Gershenzon, Jonathan, Ballaré, Carlos L., Crocco, Carlos D.“…Here, we show that Arabidopsis BBX29, a protein that belongs to the B-Box transcription factor (TF) family, integrates photomorphogenic signaling with defense responses by promoting flavonoid, sinapate and glucosinolate accumulation in Arabidopsis leaves. …”
Publicado 2023
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27968por Sun, Kai, Xue, Yuman, Zhang, Xin, Li, Xiaodong, Zhao, Jun, Xu, Xilin, Zhang, Xiaofeng, Yang, Fubiao“…Notably, TsI rescued the down-regulated expression of SRY-box transcription factor 11 (SOX11) in CD31(+) endothelial cells in the femoral heads of SIONFH rats. …”
Publicado 2023
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27969“…This work exposes an important safety issue in deep-learning-based brain disease diagnostic systems by examining the vulnerability of deep learning models for diagnosing epilepsy with brain electrical activity mappings (BEAMs) to white-box attacks. It proposes two methods, Gradient Perturbations of BEAMs (GPBEAM), and Gradient Perturbations of BEAMs with Differential Evolution (GPBEAM-DE), which generate EEG adversarial samples, for the first time by perturbing BEAMs densely and sparsely respectively, and find that these BEAMs-based adversarial samples can easily mislead deep learning models. …”
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27970por Khruengsai, Sarunpron, Promhom, Nittirat, Sripahco, Teerapong, Siriwat, Piyanuch, Pripdeevech, Patcharee“…The response surface methodology (RSM) with Plackett–Burman design (PBD) and Box-Behnken design (BBD) models were employed to optimize conditions in the EP-MAE method. …”
Publicado 2023
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27971por Ditters, Imke A. M., van Kooten, Harmke A., van der Beek, Nadine A. M. E., Hardon, Jacqueline F., Ismailova, Gamida, Brusse, Esther, Kruijshaar, Michelle E., van der Ploeg, Ans T., van den Hout, Johanna M. P., Huidekoper, Hidde H.“…Home-based ERT is unavailable in many countries because of the boxed warning alglucosidase alfa received due to the risk of infusion-associated reactions (IARs). …”
Publicado 2023
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27972por Wan, Ying, Piao, Limei, Xu, Shengnan, Meng, Xiangkun, Huang, Zhe, Inoue, Aiko, Wang, Hailong, Yue, Xueling, Jin, Xueying, Nan, Yongshan, Shi, Guo-Ping, Murohara, Toyoaki, Umegaki, Hiroyuki, Kuzuya, Masafumi, Cheng, Xian Wu“…In this setting, stressed muscle in CTSS(+/+) mice presented harmful alterations in the levels of insulin receptor substrate 2 protein content (IRS-2), phospho-phosphatidylinositol 3-kinase, phospho-protein kinase B, and phospho-mammalian target of rapamycin, forkhead box-1, muscle RING-finger protein-1 protein, mitochondrial biogenesis-related peroxisome proliferator-activated receptor-γ coactivator-α, and apoptosis-related B-cell lymphoma 2 and cleaved caspase-3; these alterations were prevented by CTSS deletion. …”
Publicado 2023
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27973“…The eight hub genes identified included interleukin-1 beta, C-X-C motif chemokine ligand 8, signal transducer and activator of transcription 3, C-C motif chemokine ligand 2, arginase 1, C-X-C motif chemokine receptor 4, cyclin D1, and matrix metallopeptidase 9, with forkhead box C1 also identified as an associated TF of these genes. …”
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27974por Qin, Dan, Wang, Rui, Ji, Jinwei, Wang, Duo, Lu, Yuanyuan, Cao, Shiyao, Chen, Yaqing, Wang, Liqiang, Chen, Xiangmei, Zhang, Lisheng“…BACKGROUND AND AIMS: Sex determining region Y related high-mobility group box protein 9 (Sox9) is expressed in a subset of hepatocytes, and it is important for chronic liver injury. …”
Publicado 2023
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27975“…The secreted Fr-DEGs identified were ceruloplasmin (CP), high mobility group box 1 (HMGB1) and transferrin (TF). The bulk RNA-seq set from the GEO database demonstrates that CP expression is increased in the PD brain. …”
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27976“…Mechanistically, CYP1B1-AS1 was regulated by the transcription factor, forkhead box O1 (FOXO1), and could be upregulated by inhibiting the PI3K/FOXO1 pathway. …”
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27977“…After analyzing the physical and chemical properties of the soil, the Box-Benken Design (BBD) technique was used to optimize the variables that influence the process's effectiveness. …”
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27978“…Using mass spectrometry, Y-box binding protein 1 (YB1) was identified as being downregulated upon inhibition of Rac1-activation in the neonatal macrophages. …”
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27979por Song, Jingyi, Duivenvoorde, Loes P. M., Grefte, Sander, Kuda, Ondrej, Martínez-Ramírez, Felipe, van der Stelt, Inge, Mastorakou, Dimitra, van Schothorst, Evert M., Keijer, Jaap“…Whole-genome transcriptome analysis revealed upregulation of forkhead box-O (FOXO) signalling, including an increased expression of tribbles pseudokinase 3 (Trib3). …”
Publicado 2023
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27980por Baek, Ji-Su, Shin, Yoon-Jung, Ma, Xiaoyang, Park, Hee-Seo, Hwang, Yun-Ha, Kim, Dong-Hyun“…They also increased AKT activation, PGC1α, SIRT1, and myosin heavy chain (MyHC) expression, MyHC-positive cell population, and cell size in the gastrocnemius (GA) muscle, while FOXO3a and NF-κB activation, MuRF1, muscle atrophy F-box, and p16 expression, and NF-κB(+)CD11c(+) cell population decreased. …”
Publicado 2023
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