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28441por Mbalinda, Scovia Nalugo, Bakeera-Kitaka, Sabrina, Amooti, Derrick Lusota, Magongo, Eleanor Namusoke, Musoke, Philippa, Kaye, Dan Kabonge“…The principles of bioethics and the four-boxes ethics framework for clinical care (patient autonomy, medical indications, the context of care, and quality of life) were used to analyze the ethical issues surrounding the transition from adolescent to adult HIV care. …”
Publicado 2021
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28442por Tackett, Alayna P, Wallace, Samantha W, Smith, Caitlin E, Turner, Elise, Fedele, David A, Stepanov, Irina, Lechner, William V, Hale, Jessica J, Wagener, Theodore L“…RESULTS: All 3 caregiver groups rated cigarettes as highly harmful (P = .14), but e-cigarette users rated all 3 types of e-cigarette products (Cartridge-based: P < .001; Tank: P < .001; Box Mod: P < .001) as less harmful than cigarette users and non-users. …”
Publicado 2021
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28443por Wei, Fang-Fei, Thijs, Lutgarde, Melgarejo, Jesus D., Cauwenberghs, Nicholas, Zhang, Zhen-Yu, Liu, Chen, Kuznetsova, Tatiana, Struijker-Boudier, Harry A. J., Verhamme, Peter, Dong, Yu-Gang, Staessen, Jan A.“…In 628 randomly recruited Flemish individuals (51.3% women; mean age, 50.8 years), we measured diastolic LV function by echocardiography and the retinal microvascular fractal dimension by the box-counting method (Singapore I Vessel Assessment software, version 3.6). …”
Publicado 2021
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28444por Jones, James Harvey, Nittur, Vinay Ravikumar, Fleming, Neal, Applegate, Richard L.“…To concurrently compare the performance of BIS and SedLine monitors, we present a data collection system using shared individual generic sensors connected to a custom-built passive interface box. METHODS: This prospective, non-blinded, non-randomized study will enroll 100 adult American Society of Anesthesiologists (ASA) class I-III patients presenting for elective procedures requiring general anesthesia. …”
Publicado 2021
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28445por Liu, Nan, Chee, Marcel Lucas, Koh, Zhi Xiong, Leow, Su Li, Ho, Andrew Fu Wah, Guo, Dagang, Ong, Marcus Eng Hock“…Moreover, they are black box models, making them difficult to explain and interpret in clinical practice.…”
Publicado 2021
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28446“…Xenograft tumor model was utilized to assess the role of X-box binding protein 1 (XBP1) in xenograft tumor growth in vivo. …”
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28447por Fan, Xing, Song, Jin-Wen, Wang, Si-Yu, Cao, Wen-Jing, Wang, Xiu-Wen, Zhou, Ming-Ju, Yang, Tao, Zhou, Chun-Bao, Hou, Jun, Zhang, Ji-Yuan, Meng, Fan-Ping, Shi, Ming, Wang, Fu-Sheng, Zhang, Chao“…Plasma damage-associated molecular patterns (DAMPs), including high mobility group box 1 (HMGB1), calprotectin (S100A8/A9), surfactant protein A (SP-A), cold-inducible RNA-binding protein (CIRBP), and Histone H4 were detected by ELISA assay, and analyzed in combination with clinical data. …”
Publicado 2021
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28448por Dasgupta, Shatavisha, Koljenović, Senada, van den Bosch, Thierry P. P., Swagemakers, Sigrid M. A., van der Hoeven, Nick M. A., van Marion, Ronald, van der Spek, Peter J., van Doorn, Helena C., van Kemenade, Folkert J., Ewing-Graham, Patricia C.“…We evaluated IHC-markers, cytokeratin 17 (CK17), and SRY-box 2 (SOX2), as diagnostic adjuncts for dVIN. For this, IHC-expression of CK17, SOX2, and p53 was studied in dVIN (n = 56), de-VIL (n = 8), and non-dysplastic vulvar tissues (n = 46). …”
Publicado 2021
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28449“…BACKGROUND: Circular RNA hsa_circ_0008305 (circPTK2), miR-181c-5p and High mobility group box-1 (HMGB1) had a targeted regulatory relationship through bioinformatics analysis. …”
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28450“…BACKGROUND: SRY-box containing gene 17 (SOX17) was reported to be a candidate tumor suppressor gene in multiple tumors. …”
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28451por Jovanovic, Vladimir M., Sarfert, Melanie, Reyna-Blanco, Carlos S., Indrischek, Henrike, Valdivia, Dulce I., Shelest, Ekaterina, Nowick, Katja“…Genes coding for zinc finger (ZNF) proteins, especially ZNFs with a Krüppel-associated box (KRAB) domain were the most abundant TFs in all genomes. …”
Publicado 2021
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28452por Rojas, Julio C., Wang, Ping, Staffaroni, Adam M., Heller, Carolin, Cobigo, Yann, Wolf, Amy, Goh, Sheng-Yang M., Ljubenkov, Peter A., Heuer, Hilary W., Fong, Jamie C., Taylor, Joanne B., Veras, Eliseo, Song, Linan, Jeromin, Andreas, Hanlon, David, Yu, Lili, Khinikar, Arvind, Sivasankaran, Rajeev, Kieloch, Agnieszka, Valentin, Marie-Anne, Karydas, Anna M., Mitic, Laura L., Pearlman, Rodney, Kornak, John, Kramer, Joel H., Miller, Bruce L., Kantarci, Kejal, Knopman, David S., Graff-Radford, Neill, Petrucelli, Leonard, Rademakers, Rosa, Irwin, David J., Grossman, Murray, Ramos, Eliana Marisa, Coppola, Giovanni, Mendez, Mario F., Bordelon, Yvette, Dickerson, Bradford C., Ghoshal, Nupur, Huey, Edward D., Mackenzie, Ian R., Appleby, Brian S., Domoto-Reilly, Kimiko, Hsiung, Ging-Yuek R., Toga, Arthur W., Weintraub, Sandra, Kaufer, Daniel I., Kerwin, Diana, Litvan, Irene, Onyike, Chiadikaobi U., Pantelyat, Alexander, Roberson, Erik D., Tartaglia, Maria C., Foroud, Tatiana, Chen, Weiping, Czerkowicz, Julie, Graham, Danielle L., van Swieten, John C., Borroni, Barbara, Sanchez-Valle, Raquel, Moreno, Fermin, Laforce, Robert, Graff, Caroline, Synofzik, Matthis, Galimberti, Daniela, Rowe, James B., Masellis, Mario, Finger, Elizabeth, Vandenberghe, Rik, de Mendonça, Alexandre, Tagliavini, Fabrizio, Santana, Isabel, Ducharme, Simon, Butler, Chris R., Gerhard, Alexander, Levin, Johannes, Danek, Adrian, Otto, Markus, Sorbi, Sandro, Cash, David M., Convery, Rhian S., Bocchetta, Martina, Foiani, Martha, Greaves, Caroline V., Peakman, Georgia, Russell, Lucy, Swift, Imogen, Todd, Emily, Rohrer, Jonathan D., Boeve, Bradley F., Rosen, Howard J., Boxer, Adam L.“…Higher baseline NfL correlated with worse longitudinal CDR+NACC-FTLD sum of boxes scores, neuropsychological function, and atrophy, regardless of genotype or disease severity, including asymptomatic mutation carriers. …”
Publicado 2021
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28453“…BACKGROUND: The expression of forkhead box protein H1 (FOXH1) is frequently upregulated in various cancers. …”
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28454“…The TAM questionnaires’ average and mean values and box plots of each data acquisition session for the children and the educators were also reported via System Usability Scale and TAM questionnaires. …”
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28455por Xu, Qi-Rong, Tang, Jian, Liao, Hong-Ying, Yu, Ben-Tong, He, Xiang-Yuan, Zheng, Yu-Zhen, Liu, Sheng“…METHODS: Gain- and loss-of-function experiments were initially performed in EC cells in addition to the establishment of a 4-nitroquinoline 1-oxide-induced EC mouse model aimed at evaluating the respective roles of forkhead box P3 (FOXP3), MEG3, miR-149-3p, mouse double minute 2 homolog (MDM2) and p53 in T cell differentiation and immune escape observed in EC. …”
Publicado 2021
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28456por Ayra, Litzy, Reyero-Saavedra, María del Rocio, Isidra-Arellano, Mariel C., Lozano, Luis, Ramírez, Mario, Leija, Alfonso, Fuentes, Sara-Isabel, Girard, Lourdes, Valdés-López, Oswaldo, Hernández, Georgina“…We propose that the positive effects of PvAGL TF in the rhizobia symbiotic processes result from its potential interplay with NIN, the master symbiotic TF regulator, that showed a CArG-box consensus DNA sequence recognized for DNA binding of AGL TF and presented an increased or decreased expression level in roots from non-inoculated plants transformed with OE_FUL or RNAi_AGL construct, respectively. …”
Publicado 2021
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28457“…Interestingly, in contrast to the short-term dynamic remodeling, the long-term morphology of the mammary gland remains remarkably stable. Together, our tool box of imaging strategies allows to identify and map transient and continuing dynamics of single cells to the architecture of the mammary gland. …”
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28458por Ni Lochlainn, Mary, Nessa, Ayrun, Sheedy, Alyce, Horsfall, Rachel, García, María Paz, Hart, Deborah, Akdag, Gulsah, Yarand, Darioush, Wadge, Samuel, Baleanu, Andrei-Florin, Whelan, Kevin, Steves, Claire“…Every participant will receive a postal box, containing their supplements, and the necessary equipment to return faecal, urine, saliva and capillary blood samples, via post. …”
Publicado 2021
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28459por Tian, Yun, Khwatenge, Collins N., Li, Jiuyi, De Jesus Andino, Francisco, Robert, Jacques, Sang, Yongming“…These CREs include not only a virus TATA-Box present in FV3 core promoters as in eukaryotic genes, but also viral mimics of CREs interacting with several transcription factors including CEBPs, CREBs, IRFs, NF-κB, and STATs, which are critical for regulation of cellular immunity and cytokine responses. …”
Publicado 2021
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28460por Wilke, Justus B. H., Hindermann, Martin, Moussavi, Amir, Butt, Umer Javed, Dadarwal, Rakshit, Berghoff, Stefan A., Sarcheshmeh, Aref Kalantari, Ronnenberg, Anja, Zihsler, Svenja, Arinrad, Sahab, Hardeland, Rüdiger, Seidel, Jan, Lühder, Fred, Nave, Klaus-Armin, Boretius, Susann, Ehrenreich, Hannelore“…Surprisingly, blood flow cytometry showed no abnormalities in circulating major immune cell subsets and plasma high-mobility group box 1 (HMGB1) as proinflammatory marker remained unchanged. …”
Publicado 2021
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