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28501“…We believe that when early release of high mobility group box 1 (HMGB1) molecules from necrotic tissues exceed their normal levels in blood, they dysregulate immune responses associated with normal healing. …”
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28502por Yu, Xin-Yi, Zhang, Zhao-Qiang, Huang, Jia-Chang, Lin, Jia-Yu, Cai, Xue-Pei, Liu, Chu-Feng“…The expressions of forkhead box P3 (Foxp3) in CD4(+)T cells and transforming growth factor (TGF-β) and IL-6 in the supernatants were determined by ELISA. …”
Publicado 2022
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28503por Pinto, Mauro, Coelho, Tiago, Leal, Adriana, Lopes, Fábio, Dourado, António, Martins, Pedro, Teixeira, César“…As these approaches create black-box models, clinicians may not have sufficient trust to use them in high-stake decisions. …”
Publicado 2022
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28504“…The participants were randomly divided into two groups (through the selection of numbers from 1 to 80, hidden in a box), with one group receiving PNE (treatment group) and the other group receiving pain biomechanics education (control group). …”
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28505por Kumar, Vikas, Kumar, Anurag, Kumar, Manish, Lone, Moien Rasheed, Mishra, Deepika, Chauhan, Shyam Singh“…By promoter deletion analysis, we identified a canonical TATA box containing 126 bp core promoter region that retained ~ 58% activity of the full length promoter. …”
Publicado 2022
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28506“…We developed and introduced a new medication administration cart in two psychiatric hospitals in Japan, in which each patient-specific drug box had to be electronically opened only by palm vein authentication. …”
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28507por Petrarca, Laura, Manganelli, Valeria, Nenna, Raffaella, Frassanito, Antonella, Ben David, Shira, Mancino, Enrica, Garofalo, Tina, Sorice, Maurizio, Misasi, Roberta, Midulla, Fabio“…A possible pro-inflammatory molecule, high-mobility group box 1 (HMGB1), may be assumed to play an important role in the pathogenesis and clinical presentation of MIS-C. …”
Publicado 2022
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28508por Anwar, Haroon, Caby, Simon, Dura-Bernal, Salvador, D’Onofrio, David, Hasegan, Daniel, Deible, Matt, Grunblatt, Sara, Chadderdon, George L., Kerr, Cliff C., Lakatos, Peter, Lytton, William W., Hazan, Hananel, Neymotin, Samuel A.“…The models using these learning rules are often treated as black boxes, with little analysis on circuit architectures and learning mechanisms supporting optimal performance. …”
Publicado 2022
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28509“…The existing genetic tool box of acetogenic bacteria bears further potential to optimize biohydrogen production in future and to contribute to a future sustainable formate/H(2) bio-economy. …”
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28510por Pu, Zhangya, Duda, Dan G., Zhu, Yuanyuan, Pei, Siya, Wang, Xiaofang, Huang, Yan, Yi, Panpan, Huang, Zebing, Peng, Fang, Hu, Xingwang, Fan, Xuegong“…The D1 domain of VCP and A box of HMGB1 were identified as the critical regions for their interaction, and D1 area was required for the tumor-promoting effects induced by VCP expression. …”
Publicado 2022
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28511“…The survey assessed the impact of specific experiences commonly reported by those affected by a rare condition through multiple choice questions and Likert scale items, and open text question boxes. Through a multi-stakeholder workshop that involved facilitated discussion of our findings with patients/carers, clinicians and a government advisor, we developed recommendations for policy and practice toward a more person-centred and integrated approach. …”
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28512“…In group A, instructions were given to the patient by the dentist while administering local anesthesia. In group B, VR box was used to show age appropriate videos according to subjects’ choice. …”
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28513por Zhai, Hong, Wan, Zhao, Jiao, Shuang, Zhou, Jingwen, Xu, Kun, Nan, Haiyang, Liu, Yingxiang, Xiong, Shangshang, Fan, Rong, Zhu, Jinlong, Jiang, Wenting, Pang, Tian, Luo, Xiao, Wu, Hongyan, Yang, Guang, Bai, Xi, Kong, Fanjiang, Xia, Zhengjun“…The expression of seven GmMDE genes (Glycine max MADS-box genes downregulated by E1) was suppressed when E1 was overexpressed and promoted when E1 was knocked out through clustered regularly-interspaced short palindromic repeats (CRISPR)/CRISPR associated protein 9 (Cas9)-mediated mutagenesis. …”
Publicado 2022
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28514por Petrone, Salvatore, Cofano, Fabio, Nicolosi, Federico, Spena, Giannantonio, Moschino, Marco, Di Perna, Giuseppe, Lavorato, Andrea, Lanotte, Michele Maria, Garbossa, Diego“…METHODS: The neurosurgical simulator used in this study (UpSurgeOn Box, UpSurgeOn Srl, Assago, Milan) combines a virtual component and a physical component with an intermediate step to provide a hybrid solution. …”
Publicado 2022
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28515por Abdellaoui, Nawel, Abdelmoula, Balkiss, Abdelhedi, Rania, Kharrat, Najla, Tabebi, Mouna, Rebai, Ahmed, Bouayed Abdelmoula, Nouha“…The expression of UGT1A1 is relatively managed by a polymorphic dinucleotide repeat inside the promoter TATA box consisting of 5–8 copies of a TA repeat. A (TA) 6TAA is considered as the wild type. …”
Publicado 2022
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28516“…GSDMD damped cGAS activation by promoting autophagy via outputting potassium (K+) and promoted programmed death ligand-1 (PD-L1) expression by histone deacetylases/signal transducer and activator of transcription 1 (STAT1)-induced transactivation of PD-L1 via importing calcium (Ca2+). High Mobility Group Box 1/toll-like receptor 4 (TLR4)/caspase-1 pathway contributed to the overexpression and cleavage of GSDMD. …”
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28517por Ngoutane, Raphia, van Zutphen, Kesso Gabrielle, Razakandrainy, Andry, Takanashi, Kumiko, Zoma, Ramakwende, Bajoria, Madhavika, Bruning, Rachel, Desilets, Marie-Claude, Dalmiya, Nita, Kraemer, Klaus, Kodish, Stephen“…In this setting, women voted for an orange-colored MMS box design because the color reflects locally-available fruits such as mangoes and oranges. …”
Publicado 2022
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28518“…Participants selected the product set (the three above, plus the full set of 33 cereals) they wished to view to choose a box of cereal from. Participants later were asked how healthy, tasty, and costly they believed the cereals from each subset were on average We estimate a multinomial logistic regression model using R software. …”
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28519por Zhu, Lihui, Liao, Rongrong, Huang, Jiwen, Yan, Huaxiang, Xiao, Changfeng, Yang, Yunzhou, Wang, Huiying, Yang, Changsuo“…Furthermore, the dual luciferase gene reporter assay and RT-qPCR analysis demonstrated that 3-hydroxyacyl-CoA dehydratase 2, F-box protein 8, and transmembrane 9 superfamily member 3 (TM9SF3) were directly targeted by miR-216a/b and miR-217-5p, respectively, and suppressed in the fatty livers of laying hens. …”
Publicado 2022
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28520por Qu, Fufa, She, Qing, Li, Jialing, Zeng, Xuan, Li, Yumiao, Liu, Xinyu, Ren, Lingxin, Liu, Zhenzhen, Gao, Chaoran, Lu, Xinyu, Long, Mengyao, Li, Xinya“…The present AwMyD88 protein consists of 474 amino acids and contains a conserved a typical death domain (DD) and a conservative Toll/IL-1R (TIR) domain with three typical boxes. Quantitative real-time PCR (qRT-PCR) analysis showed that AwMyD88 was broadly expressed in all the examined tissues, and the highest expression level was observed in hemocytes of A. woodiana. …”
Publicado 2022
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