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  1. 28521
    por Wray, Tyler B
    Publicado 2022
    “…The most commonly recommended app or website was SMARTRecovery.org (9%), I am Sober (8%), In the Rooms (7%), Insight Timer (4%), Calm (4%), Sober Tool (4%), Recovery Box (3%), and Sober Grid (3%). The most important reason that counselors recommended the websites or apps was that colleagues or patients told them they found it helpful (55%), followed by their workplaces recommending it (20%) and professional organizations recommending it (10%). …”
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    Online Artículo Texto
    Exploring Whether Addictions Counselors Recommend That Their Patients Use Websites, Smartphone Apps, or Other Digital Health Tools to Help Them in Their Recovery: Web-Based Survey
  2. 28522
    “…Nevertheless, the role of circRNAs derived from forkhead box M1 (FOXM1), a well-accepted modulator of OS progression, has not been discussed in OS. …”
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    Circ-FOXM1 promotes the proliferation, migration and EMT process of osteosarcoma cells through FOXM1-mediated Wnt pathway activation
  3. 28523
    por Tori, Sara, Pappers, Jesse, Keserü, Imre
    Publicado 2022
    “…Lastly, we found that children have many outside-of-the-box suggestions when it comes to the future. Although some of their ideas can be judged as impractical by today’s standards, many ideas had an indirect implication for mobility in the village and gave insights into children’s priorities, as potential future residents of the village.…”
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    Developing disruptive mobility scenarios for rural areas. Participatory mobility scenario building in a Belgian village for the year 2050
  4. 28524
    “…Tumor tissues disseminated in the peritoneum 4 weeks after injection were used for histological examination with hematoxylin and eosin (H&E) and paired-box gene 8 (PAX-8) staining. RESULTS: In the phase I trial, two piglets showed PM with modified PCI scores of 5 and 4 at 3 weeks after the first inoculation, which increased to 14 and 15 after 4 weeks, respectively. …”
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    Establishment of a piglet model for peritoneal metastasis of ovarian cancer
  5. 28525
    “…To weaken SRF interactions with NKX2.5 and GATA4, one mutant, SRF153(A3) named STEMIN, did not bind CArG boxes, yet induced stem cell factors such as NANOG and OCT4, cardiomyocyte dedifferentiation, and cell cycle reentry. …”
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    STEMIN and YAP5SA synthetic modified mRNAs regenerate and repair infarcted mouse hearts
  6. 28526
    “…Walking performance was assessed with wearable sensors under single (ST; fast and normal pace) and dual-task (DT; walking and checking boxes as the motor secondary task and walking and subtracting seven consecutively from a given three-digit number as the cognitive secondary task) conditions over 20 m. …”
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    Does Executive Function Influence Walking in Acutely Hospitalized Patients With Advanced Parkinson's Disease: A Quantitative Analysis
  7. 28527
    “…MEASUREMENTS AND MAIN RESULTS: The gene expression of toll-like receptor (TLR)2 and TLR4 (inflammatory receptors), NLRP3, NFκB1, adaptor molecule apoptosis-associated speck-like protein containing a CARD, caspase 1, caspase 11, and caspase 12 (NLRP3 inflammasome components), interleukin-1α, interleukin-1β, interleukin-18, and high-mobility group box 1 protein (proinflammatory cytokines), interleukin-10 (anti-inflammatory cytokine), C-X-C motif chemokine ligand 10, C-X-C motif chemokine ligand 11, and interleukin-12p35 (M1 inflammatory polarization markers), and C-C motif chemokine ligand 14, C-C motif chemokine ligand 22, transforming growth factor-beta (TGF-β), SR-B1, and peroxisome proliferator-activated receptor γ (M2 anti-inflammatory polarization and tissue repair markers) was upregulated in monocytes from phase A until phase E compared with the control group. …”
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    Evidence for Monocyte Reprogramming in a Long-Term Postsepsis Study
  8. 28528
    “…Medians and interquartile ranges (IQR) were represented by box plots. Multivariable logistic regression was performed obtaining an odds ratio (OR), 95% CI, and further adjusted to discover the independent predictors and risk factors associated with elevated NLR and dNLR. …”
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    Comparative analysis of neutrophil to lymphocyte ratio and derived neutrophil to lymphocyte ratio with respect to outcomes of in-hospital coronavirus disease 2019 patients: A retrospective study
  9. 28529
    “…Other than various PAMPs, MS19 also demonstrated obvious effects on blocking the high mobility group box1 (HMGB1), a representative damage-associated-molecular pattern (DAMP), nuclear translocation and secretion. …”
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    A microsatellite DNA-derived oligodeoxynucleotide attenuates lipopolysaccharide-induced acute lung injury in mice by inhibiting the HMGB1-TLR4-NF-κB signaling pathway
  10. 28530
    “…Variables, such as age, education, the scores of visuospatial and memory domains, the sum of boxes of the Clinical Dementia Rating scale, Mini-Mental State Examination, and APOE genotype were important features for creating the algorithm. …”
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    Prediction of conversion to dementia using interpretable machine learning in patients with amnestic mild cognitive impairment
  11. 28531
    “…We demonstrate that the role of the MADS-box transcription factor FaSOC1 as a strong repressor of flowering and promoter of vegetative growth is conserved in woodland and cultivated strawberry. …”
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    Role of FaSOC1 and FaCO in the seasonal control of reproductive and vegetative development in the perennial crop Fragaria × ananassa
  12. 28532
    por van der Ende, Emma L., Heller, Carolin, Sogorb-Esteve, Aitana, Swift, Imogen J., McFall, David, Peakman, Georgia, Bouzigues, Arabella, Poos, Jackie M., Jiskoot, Lize C., Panman, Jessica L., Papma, Janne M., Meeter, Lieke H., Dopper, Elise G. P., Bocchetta, Martina, Todd, Emily, Cash, David, Graff, Caroline, Synofzik, Matthis, Moreno, Fermin, Finger, Elizabeth, Sanchez-Valle, Raquel, Vandenberghe, Rik, Laforce, Robert, Masellis, Mario, Tartaglia, Maria Carmela, Rowe, James B., Butler, Chris, Ducharme, Simon, Gerhard, Alexander, Danek, Adrian, Levin, Johannes, Pijnenburg, Yolande A. L., Otto, Markus, Borroni, Barbara, Tagliavini, Fabrizio, de Mendonça, Alexandre, Santana, Isabel, Galimberti, Daniela, Sorbi, Sandro, Zetterberg, Henrik, Huang, Eric, van Swieten, John C., Rohrer, Jonathan D., Seelaar, Harro
    Publicado 2022
    “…In symptomatic carriers, correlations were additionally observed with disease duration and with Mini Mental State Examination and Clinical Dementia Rating scale® plus NACC Frontotemporal lobar degeneration sum of boxes scores. CONCLUSIONS: Elevated levels of CSF C1q and C3b, as well as plasma C2 and C3, demonstrate the presence of complement activation in the symptomatic stage of genetic FTD. …”
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    Elevated CSF and plasma complement proteins in genetic frontotemporal dementia: results from the GENFI study
  13. 28533
    “…BACKGROUND: High-mobility group box 1 protein (HMGB1) is an ubiquitous nuclear protein that once released in the extracellular space acts as a Damage Associated Molecular Pattern and promotes inflammation. …”
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    Pamoic acid is an inhibitor of HMGB1·CXCL12 elicited chemotaxis and reduces inflammation in murine models of Pseudomonas aeruginosa pneumonia
  14. 28534
    “…Safety and tolerability will be assessed through an adverse events survey, the Box and Blocks Test (BBT) motor assessment, and a setup ease/comfort survey. …”
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    Remotely monitored transcranial direct current stimulation in pediatric cerebral palsy: open label trial protocol
  15. 28535
    “…The levels of circ_0008365, SRY-related high mobility group-box gene9 (SOX9) mRNA, and microRNA-338-3p (miR-338-3p) were detected by quantitative real-time polymerase chain reaction (qRT-PCR) assay. …”
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    Circular RNA circ_0008365 regulates SOX9 by targeting miR-338-3p to inhibit IL-1β-induced chondrocyte apoptosis and extracellular matrix degradation
  16. 28536
    “…Aberrant testicular miR-34c, a germ-specific miRNA, and miR-155 expressions were observed, along with decreased protein expression of sirtuin1 (SIRT1) dependent forkhead box 1 (FOXO1) acetylation which induces apoptosis. …”
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    Inflammatory Modulation of miR-155 Inhibits Doxorubicin-Induced Testicular Dysfunction via SIRT1/FOXO1 Pathway: Insight into the Role of Acacetin and Bacillus cereus Protease
  17. 28537
    “…BACKGROUND: Forkhead-Box-Protein P3 (FoxP3) is a transcription factor and marker of regulatory T cells, converting naive T cells into Tregs that can downregulate the effector function of other T cells. …”
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    FoxP3 expression by retinal pigment epithelial cells: transcription factor with potential relevance for the pathology of age-related macular degeneration
  18. 28538
    “…Finally, the methods including data augmentation, Test Time Augmentation (TTA) and Weighted Boxes Fusion (WBF) were used to improve the robustness and generalization of the model for the identification of terminal buds in different growth states. …”
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    Recognition of terminal buds of densely-planted Chinese fir seedlings using improved YOLOv5 by integrating attention mechanism
  19. 28539
    “…METHODS: Three hundred general practitioners and 300 pain specialists in Germany—enrolled separately in two independent exploratory randomized controlled online trials—were randomly assigned to either a descriptive format (fact box) or a simulated-experience format (interactive simulation). …”
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    Educating physicians on strong opioids by descriptive versus simulated-experience formats: a randomized controlled trial
  20. 28540
    “…CGMCC3.5218 degraded more than 85.0% of total aflatoxins (aflatoxin B(1), B(2), G(1), and G(2)) at 108.2–2323.5 ng/kg in artificially and naturally contaminated peanut, maize, and feed within 7 days. Box–Behnken design and response surface methodology showed that the optimal degradation conditions for CGMCC3.5218 were pH 6.7 and 31.3°C for 5.1 days in liquid medium. …”
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    Characterization and mechanism of aflatoxin degradation by a novel strain of Trichoderma reesei CGMCC3.5218
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