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28921por Adomavičienė, Aušra, Daunoravičienė, Kristina, Kubilius, Raimondas, Varžaitytė, Lina, Raistenskis, Juozas“…Functional recovery was compared among groups using the Functional Independence Measure (FIM), and upper limbs’ motor function recovery was compared using the Fugl–Meyer Assessment Upper Extremity (FMA-UE), Modified Ashworth Scale (MAS), Hand grip strength (dynamometry), Hand Tapping test (HTT), Box and Block Test (BBT), and kinematic measures (active Range Of Motion (ROM)), while cognitive functions were assessed by the MMSE (Mini-Mental State Examination), ACE-R (Addenbrooke’s Cognitive Examination-Revised), and HAD (Hospital Anxiety and Depression Scale) scores. …”
Publicado 2019
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28922por Micó-Amigo, M. Encarna, Kingma, Idsart, Heinzel, Sebastian, Nussbaum, Susanne, Heger, Tanja, van Lummel, Rob C., Berg, Daniela, Maetzler, Walter, van Dieën, Jaap H.“…The aim of this study was to quantitatively identify markers of progressive gait deficits in idiopathic PD while walking over a circular trajectory condition in single-task walking and in different dual-task conditions: (1) circular walking while checking boxes on a paper sheet as fast as possible and (2) circular walking while performing subtraction of 7 as fast as possible. …”
Publicado 2019
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28923“…Animals were exposed to a predator (cat) for 10 min and enduring avoidance behaviors were examined in the open field, light-dark box, and “trauma-reminder” tests 1–2 weeks later. …”
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28924“…Quantitative real-time PCR (qRT-PCR) and western blot were performed to measure the mRNA expressions of SIRT1 and Forkhead box O1 (FOXO1). Nicotinamide (NAM) and AS1842856 were used to inhibit activities of SIRT1 and FOXO1, respectively. …”
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28925“…None can be executed in parallel out of the box and very few have features to support visual review of new elements. …”
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28926por Keis, Oliver, Schneider, Achim, Heindl, Felix, Huber-Lang, Markus, Öchsner, Wolfgang, Grab-Kroll, Claudia“…These placements are an extracurricular activity, however, and regarded as the “black box” of medical education. This study aimed to evaluate whether and how students experience role models during clinical placements, the qualities associated with potential role models and whether role model-related learning gains are relevant. …”
Publicado 2019
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28927SAT-354 Characterization of Cell Death Induced by SOAT1 Inhibition in Adrenocortical Carcinoma Cellspor Weigand, Isabel, Schreiner, Jochen, Roehrig, Florian, Hoefner, Kerstin, Kendl, Sabine, Fassnacht, Martin, Sbiera, Silviu, Kroiss, Matthias“…Correspondingly, expression of ER-stress marker CHOP and splicing of X-box protein 1 mRNA was activated by mitotane, ATR101 and poorly by AZD3988. …”
Publicado 2019
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28928“…Immunohistochemistry was positive for Paired Box Gene 8 (PAX8) and Cytokeratin 7 (CK7). As PAX8 is specific for thyroid cancer, the pleural effusions were thought to be metastatic adenocarcinoma from anaplastic dedifferentiation of papillary thyroid cancer. …”
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28929por Stenz, Ludwig, Rahban, Rita, Prados, Julien, Nef, Serge, Paoloni-Giacobino, Ariane“…In FVB/N, analysis of non-synonymous single nucleotide polymorphisms (SNP) impacting SHP identified rs387782768 and rs29315913 respectively associated with absence of the Forkhead Box A3 (Foxa3) RNA and increased expression of estrogen receptor 1 variant 4 (NM_001302533) RNA. …”
Publicado 2019
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28930por Wei, Dongyi, Wang, Weixin, Shen, Baohong, Zhou, Yanjun, Yang, Xiaodong, Lu, Guangjian, Yang, Jianbin, Shao, Yuebao“…Notably, the results revealed that the EMT-related transcription factor SRY-box 4 (SOX4) was a direct target gene of miR-199a-5p, as determined by the direct binding of miR-199a-5p with the 3′-untranslated region of SOX4. …”
Publicado 2019
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28931por Kisling, Kelly, Johnson, Jennifer L., Simonds, Hannah, Zhang, Lifei, Jhingran, Anuja, Beadle, Beth M., Burger, Hester, du Toit, Monique, Joubert, Nanette, Makufa, Remigio, Shaw, William, Trauernicht, Christoph, Balter, Peter, Howell, Rebecca M., Schmeler, Kathleen, Court, Laurence“…The steps involved in the workflow of planning a four‐field box treatment of cervical cancer with the RPA were identified. …”
Publicado 2019
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28932“…Both Sgk1 and Klf2 were enriched in the ‘forkhead box O (FoxO) signaling pathway’, and Sgk1 was additionally enriched in the ‘mechanistic target of rapamycin kinase (mTOR) signaling pathway’. …”
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28933“…Therefore, the present study examined the prognostic significance of ATAD3 gene cluster expression in patients with HCC. Box plots of expression differences between HCC and normal liver tissues for the ATAD3 family genes were obtained from the online tool Gene Expression Profiling Interactive Analysis. …”
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28934por Mera, Jorge, Joshi, Kartik, Thornton, Karla, Box, Terry, Scott, John, Sedillo, Miranda, Deming, Paulina, David, Crystal, Essex, Whitney, Manch, Richard, Kohli, AnitaEnlace del recurso
Publicado 2019
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28935“…The SNP, g.8344262A > T, was predicted to alter the binding site (BS) of transcription factor (TF) GAGA box with Genomatix software, and the subsequent luciferase assay verified that it really changed the transcriptional activity of PRKG1 gene (P = 0.0009). …”
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28936por Wang, Yun‐Long, Liu, Jin‐Yu, Yang, Jin‐E, Yu, Xiao‐Man, Chen, Zhan‐Li, Chen, Ya‐Jing, Kuang, Ming, Zhu, Ying, Zhuang, Shi‐Mei“…Mechanistically, the 850‐1030‐nt domain of lnc‐UCID interacted physically with DEAH (Asp‐Glu‐Ala‐His) box helicase 9 (DHX9), an RNA helicase. On the other hand, DHX9 post‐transcriptionally suppressed CDK6 expression by binding to the 3′‐untranslated region (3′UTR) of CDK6 mRNA. …”
Publicado 2019
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28937Evidence for SIRT1 Mediated HMGB1 Release From Kidney Cells in the Early Stages of Hemorrhagic Shockpor Xu, Siqi, Zeng, Zhenhua, Zhao, Ming, Huang, Qiaobing, Gao, Youguang, Dai, Xingui, Lu, Jiayin, Huang, Weiqing, Zhao, Keseng“…BACKGROUND: This study is to explore the effect of SIRT1 deacetylating inactivation on organ-derived high mobility group box 1 (HMGB1) during the development of severe hemorrhagic shock (HS). …”
Publicado 2019
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28938por Huang, Senlin, Li, Xinzhong, Zheng, Hao, Si, Xiaoyun, Li, Bing, Wei, Guoquan, Li, Chuling, Chen, Yijin, Chen, Yanmei, Liao, Wangjun, Liao, Yulin, Bin, Jianping“…Mechanistically, circNfix reinforced the interaction of Ybx1 (Y-box binding protein 1) with Nedd4l (an E3 ubiquitin ligase), and induced Ybx1 degradation through ubiquitination, repressing cyclin A2 and cyclin B1 expression. …”
Publicado 2019
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28939por Yang, Qingqiu, Pinto, Vanessa Marigo Rocha, Duan, Wei, Paxton, Erica E., Dessauer, Jenna H., Ryan, William, Lopez, Mandi J.“…Gene expression of CD105, CD44, K14, K15, sex determining region Y-box 2 (SOX2) and octamer-binding transcription factor 4 (OCT4) was confirmed in vitro. …”
Publicado 2019
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28940por Grünberger, Felix, Reichelt, Robert, Bunk, Boyke, Spröer, Cathrin, Overmann, Jörg, Rachel, Reinhard, Grohmann, Dina, Hausner, Winfried“…Interrogation of the distances between pTSSs and aTSSs revealed a significant number of antisense transcripts, which are a result of bidirectional transcription from the same TATA box. This mechanism of antisense transcript production could be further confirmed by in vitro transcription experiments. …”
Publicado 2019
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