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29021“…The myosin heavy chain (MHC), muscle atrophy F-box, and muscle ring-finger protein-1 protein levels did not significantly differ (P = 0.324, 0.552, and 0.352, respectively). …”
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29022por Corbett, Teresa K., Cummings, Amanda, Lee, Kellyn, Calman, Lynn, Fenerty, Vicky, Farrington, Naomi, Lewis, Lucy, Young, Alexandra, Boddington, Hilary, Wiseman, Theresa, Richardson, Alison, Foster, Claire, Bridges, Jackie“…Concerns were raised about possible extra work for those receiving or delivering care, time and staffing, and risk of creating another “tick-box” exercise for staff. Participants concluded that anyone with the appropriate skills could potentially deliver the intervention, but training was likely to be required to ensure correct utilisation and self-efficacy to deliver to the intervention. …”
Publicado 2020
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29023por Zhang, Yaowen, Fornes, Balbino, Gómez, Gabriela, Bentoldrà, Irene, Carmona, Clara, Herreros, Antonio, Sabater, Sebastià, Nicolás, Inmaculada, Li, Yan, Sánchez, Joan, Biete, Albert, Torné, Aureli, Ascaso, Carlos, Rovirosa, Ángeles“…Statistics: frequency tables, mean, median, range, standard deviation, and box plot. Results: The median follow-up was 51 months (12–68). 20 p (46.5%) and 2 p (4.7%) developed G1 and G2 vaginal complications, respectively. …”
Publicado 2020
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29024por Webb, Alastair J.S., Lawson, Amy, Wartolowska, Karolina, Mazzucco, Sara, Rothwell, Peter M.“…METHODS: In consecutive patients within 6 weeks of transient ischemic attack or nondisabling stroke (OXVASC [Oxford Vascular Study]), arterial stiffness (pulse wave velocity [PWV]) and aortic systolic, aortic diastolic, and aortic pulse pressures (aoPP) were measured by applanation tonometry (Sphygmocor), while middle cerebral artery (MCA) peak (MCA-PSV) and trough (MCA-EDV) flow velocity and Gosling pulsatility index (PI; MCA-PI) were measured by transcranial ultrasound (transcranial Doppler, DWL Doppler Box). Repeat assessments were performed at the 5-year follow-up visit after intensive medical treatment and agreement determined by intraclass correlation coefficients. …”
Publicado 2021
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29025“…Binary variables recorded past year participation in 19 different gambling forms, ranging from lotteries to online casino and gambling-like practices within digital games (e.g. loot box purchase, skin betting). Controls included socio-demographic/economic characteristics, the Eysenck Impulsivity Scale and the number of gambling activities undertaken. …”
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29026por Jin, Wangdong, Gu, Chaoqun, Zhou, Li, Yang, Xinyu, Gui, Mengyuan, Zhang, Jin, Chen, Jie, Dong, Xiaoqiao, Yuan, Qiang, Shan, Letian“…The results of WB analysis revealed that TB significantly regulated key molecules of epithelial-mesenchymal transition [EMT; e.g., E-cadherin, vimentin, Snail-1, Slug and zinc finger E-box-binding homeobox 1 (ZEB-1)] and those of the nuclear factor (NF)-κB pathway (e.g., NF-κB, phospho-IKKα and phospho-IKKβ), indicating that NF-κB pathway-related EMT suppression may mediate the mechanisms underlying the anti-migratory and anti-invasive effects of TB against osteosarcoma. …”
Publicado 2020
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29027por Li, YiQiang, Lin, XueMei, Zhu, MingWei, Xun, FuXing, Li, JingChun, Yuan, Zhe, Liu, YanHan, Xu, HongWen“…The expression of aggrecan (Acan), α-1 chain of type II collagen (COL2A1), and SRY-box transcription factor 9 (SOX9) were higher in MUT group than WT group. …”
Publicado 2020
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29028por Li, Yuping, Liang, Xiaoju, Zhou, Xuguo, Wu, Zhigeng, Yuan, Ling, Wang, Ying, Li, Yongqing“…The expression profiles of 14 candidate reference genes, including Actin1 (ACT), Clathrin complex AP1 (CAC), Cyclophilin (CYP), Heat-shock protein 40 (DNAJ), Dehydration responsive element binding gene (DREB), Translation elongation factor1 (EF1), Ras related protein (RAN), Translation initiation factor (TIF1), β-Tubulin (TUB), Ubiquitin-conjugating enzyme E2 (UBC2), ATP binding-box transpoter 2 (ABCC2), COP9 signal compex subunit 3 (COPS3), Citrate synthase (CS), and R3H domain protein 2 (R3HDM2) from two congeneric species, Glycyrrhiza uralensis F. and Glycyrrhiza inflata B., were examined under abiotic stresses (osmotic and salinity) and hormonal treatments (Abscisic acid (ABA) and methyl jasmonic acid (MeJA)) using a panel of software, including geNorm, NormFinder, BestKeeper, and Delta CT. …”
Publicado 2020
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29029por Edouard, Pascal, Sanchez, Hervé, Bourrilhon, Cyprien, Homo, Sébastien, Frère, Julien, Cassirame, Johan“…One biomechanical parameter related to the take-off phase (lower H2, i.e., height of the grip (superior) hand from the ground when the athlete subsequently took off from the ground) and some biomechanical parameters related to the terminal phase of the run-up phase (higher Spd [i.e., speed between 10 and 5 meters to the box), SL(adj) (last stride adjustment), SL(var) (stride length variation), t(c) (contact time)] were significantly associated with higher proportions of all injuries. …”
Publicado 2019
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29030por Hannestad, Jonas, Koborsi, Katie, Klutzaritz, Vicki, Chao, Whitney, Ray, Rebecca, Páez, Antonio, Jackson, Sam, Lohr, Scott, Cummings, Jeffrey L., Kay, Gary, Nikolich, Karoly, Braithwaite, Steven“…The mean change from baseline on the Category Fluency Test, Clinical Dementia Rating Scale–Sum of Boxes, Alzheimer's Disease Cooperative Study–Clinical Global Impression of Change, and Neuropsychiatric Inventory Questionnaire was similar for both treatment groups and did not show any worsening. …”
Publicado 2020
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29031por Jinnai, Masako, Koning, Gabriella, Singh-Mallah, Gagandeep, Jonsdotter, Andrea, Leverin, Anna-Lena, Svedin, Pernilla, Nair, Syam, Takeda, Satoru, Wang, Xiaoyang, Mallard, Carina, Ek, Carl Joakim, Rocha-Ferreira, Eridan, Hagberg, Henrik“…At P40, GMH rats spent more time in the center of open field box and moved at higher speed compared to the controls, and continued to show ipsilateral injury in striatum and subcortical white matter. …”
Publicado 2020
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29032por Hasmatali, Jovan C.D., De Guzman, Jolly, Johnston, Jayne M., Noyan, Hossein, Juurlink, Bernhard H., Misra, Vikram, Verge, Valerie M.K.“…Stress-induced nuclear translocation of the transcription factor forkhead class box O3a (FOXO3a) was initially linked to activation of apoptotic genes in many neuronal subtypes. …”
Publicado 2020
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29033“…Using perfusion analysis software (VueBox ®), eleven parameters were collected, and intra-class correlation coefficient (ICC) was used to analyze reproducibility. …”
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29034por Suwik, Katarzyna, Sinderewicz, Emilia, Boruszewska, Dorota, Kowalczyk-Zięba, Ilona, Staszkiewicz-Chodor, Joanna, Łukaszuk, Krzysztof, Wocławek-Potocka, Izabela“…The expression of PPARδ and PPARγ was correlated with the expression of quality markers in bovine blastocysts [sex-determining region Y-box 2 (SOX2), octamer-binding transcription factor 4 (OCT4), placenta-specific 8 (PLAC8), insulin-like growth receptor (IGF1R)]. …”
Publicado 2020
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29035por Tanabe, Shihori, Quader, Sabina, Ono, Ryuichi, Cabral, Horacio, Aoyagi, Kazuhiko, Hirose, Akihiko, Yokozaki, Hiroshi, Sasaki, Hiroki“…Our analysis uncovered 10 genes including male-specific lethal 3 homolog (Drosophila) pseudogene 1 (MSL3P1), CDC28 protein kinase regulatory subunit 1B (CKS1B), DEAD-box helicase 27 (DDX27), golgi to ER traffic protein 4 (GET4), chromosome segregation 1 like (CSE1L), translocase of outer mitochondrial membrane 34 (TOMM34), YTH N6-methyladenosine RNA binding protein 1 (YTHDF1), ribonucleic acid export 1 (RAE1), par-6 family cell polarity regulator beta (PARD6B), and MRG domain binding protein (MRGBP), which have differences in gene expression between intestinal- and diffuse-type GC. …”
Publicado 2020
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29036por Nitta, Suguru, Hisasue, Masaharu, Horiguchi, Yu, Yamada, Yoko, Kikuchi, Kaoruko, Kubo, Takeaki, Igarashi, Hirotaka, Neo, Sakurako“…METHODS: The iHep cells were prepared by introducing two genes, namely, the Forkhead box A1 (Foxa1) and hepatocyte nuclear factor 4 homeobox alpha (Hnf4α), into cBMSCs seeded onto an ultra-low attachment microplate to induce spheroid formation. …”
Publicado 2020
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29037“…However, the function of circ_0006404 (circRNA Forkhead box O3 (circFOXO3)in prostate cancer (PCa) is poorly understood. …”
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29038por Yao, Yaxin, Pan, Zhangyuan, Di, Ran, Liu, Qiuyue, Hu, Wenping, Guo, Xiaofei, He, Xiaoyun, Gan, Shangquan, Wang, Xiangyu, Chu, Mingxing“…It can affect reproduction by binding the promoters of estrogen-regulated genes, such as FOXA1 (forkhead box A1) and ESR1 (estrogen receptor 1). Notably, one nonsynonymous mutation (p.S936A) specific to the high-prolificacy group was identified at the TUDOR domain of KDM4B. …”
Publicado 2021
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29039por Chen, Dan, Zhang, Cheng, Chen, Jiangyong, Yang, Mei, Afzal, Tayyab A, An, Weiwei, Maguire, Eithne M, He, Shiping, Luo, Jun, Wang, Xiaowen, Zhao, Yu, Wu, Qingchen, Xiao, Qingzhong“…Further mechanistic studies revealed that FERM2 suppresses smooth muscle gene expression by preventing serum response factor nuclear translocation and preventing endothelial mRNA decay by interacting with Y‐box binding protein 1. In a model of aortic grafting using endothelial lineage tracing, we observed that miR‐200c‐3p expression was dramatically up‐regulated, and that EndoMT contributed to neointimal hyperplasia in grafted arteries. …”
Publicado 2020
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29040por Shah, Shagun B, Chawla, Rajiv, Pahade, Akhilesh, Mittal, Amit, Bhargava, Ajay K, Kumar, Rajeev“…Data were subjected to statistical analysis using the Statistical Package for Social Sciences, version-23 and independent sample t-test/Welch test for equality of means and expressed as dotted box-whisker plots. Nominal categorical intergroup data was compared using Chi-squared test/Fisher's exact test. …”
Publicado 2020
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