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29301por Peng, Shiqiao, Li, Chenyan, Wang, Xinyi, Liu, Xin, Han, Cheng, Jin, Ting, Liu, Shanshan, Zhang, Xiaowen, Zhang, Hanyi, He, Xue, Xie, Xiaochen, Yu, Xiaohui, Wang, Chuyuan, Shan, Ling, Fan, Chenling, Shan, Zhongyan, Teng, Weiping“…TLR2, TLR3, TLR9, high mobility group box 1 (HMGB1), and RAGE expression on monocytes was higher in patients than control at baseline and TLR agonists’ stimulation. …”
Publicado 2016
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29302por Zhong, Wu, Jiang, Zhi-Yuan, Zhang, Lei, Huang, Jia-Hao, Wang, Shi-Jun, Liao, Cun, Cai, Bin, Chen, Li-Sheng, Zhang, Sen, Guo, Yun, Cao, Yun-Fei, Gao, Feng“…Expression of phenotypic markers such as forkhead box (Fox)p3, cytotoxic T-lymphocyte-associated protein (CTLA)-4, chemokine CC receptor (CCR)4 and CCR5 was measured using flow cytometry. …”
Publicado 2017
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29303por Song, Guoqi, Zhang, Rongzhi, Zhang, Shujuan, Li, Yulian, Gao, Jie, Han, Xiaodong, Chen, Mingli, Wang, Jiao, Li, Wei, Li, Genying“…Since many targets of differentially expressed miRNAs were transcription factors that are associated with floral development such as ARF, SPB (Squamosa Promoter Binding like protein), MADS-box (MCM1, AG, DEFA and SRF), MYB, SPX (SYG1, Pho81 and XPR1), TCP (TEOSINTE BRANCHED, Cycloidea and PCF), and PPR (PentatricoPeptide Repeat) genes, cold-altered miRNA expression may cause abnormal reproductive organ development. …”
Publicado 2017
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29304por Cheng, Joyce Y., Brown, Taylor C., Murtha, Timothy D., Stenman, Adam, Juhlin, C. Christofer, Larsson, Catharina, Healy, James M., Prasad, Manju L., Knoefel, Wolfram T., Krieg, Andreas, Scholl, Ute I., Korah, Reju, Carling, Tobias“…DKK3-over-expressing cells also showed increased expression of Forkhead Box Protein O1 (FOXO1) transcription factor, RNAi silencing of which partially restored the migratory proficiency of cells without interfering with their viability. …”
Publicado 2017
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29305por Wong, Yick Ching, Teh, Huey Fang, Mebus, Katharina, Ooi, Tony Eng Keong, Kwong, Qi Bin, Koo, Ka Loo, Ong, Chuang Kee, Mayes, Sean, Chew, Fook Tim, Appleton, David R., Kulaveerasingam, Harikrishna“…These differentially expressed genes comprise several transcription factors, such as, bHLH, Dof zinc finger proteins and MADS box proteins. Several genes involved in glycolysis, TCA, and fatty acid biosynthesis pathways were also found up-regulated in high-yielding oil palm, among them; pyruvate dehydrogenase E1 component Subunit Beta (PDH), ATP-citrate lyase, β- ketoacyl-ACP synthases I (KAS I), β- ketoacyl-ACP synthases III (KAS III) and ketoacyl-ACP reductase (KAR). …”
Publicado 2017
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29306por Maciaczyk, D, Picard, D, Zhao, L, Koch, K, Herrera-Rios, D, Li, G, Marquardt, V, Pauck, D, Hoerbelt, T, Zhang, W, Ouwens, D M, Remke, M, Jiang, T, Steiger, H J, Maciaczyk, J, Kahlert, U D“…CBF1 inhibition blocks EMT activators such as zinc finger E-box-binding homeobox 1 (ZEB1) and significantly reduces cellular invasion and resistance to clinically approved anticancer drugs. …”
Publicado 2017
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29307por Yuan, Jingwei, Chen, Sirui, Shi, Fengying, Wu, Guiqin, Liu, Aiqiao, Yang, Ning, Sun, Congjiao“…Bioinformatics analysis further revealed that gga-mir-15a could act on many target genes, such as forkhead box O1 (FOXO1) that is involved in the insulin-signaling pathway, which influences nutrient metabolism in many organisms. …”
Publicado 2017
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29308“…Here, we investigated the role of miR-129-5p after spinal cord IR, particularly in regulating high-mobility group box-1 (HMGB1) and the Toll-like receptor (TLR)-3 pathway. …”
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29309por Rupp, M, Hagenbuchner, J, Rass, B, Fiegl, H, Kiechl-Kohlendorfer, U, Obexer, P, Ausserlechner, M J“…Forkhead box O class transcription factors are homeostasis regulators that control cell death, longevity and therapy-resistance. …”
Publicado 2017
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29310por St. Laurent, Brandyce, Sukowati, Supratman, Burton, Timothy A., Bretz, David, Zio, Mulyadi, Firman, Syah, Sumardi, Sudibyo, Heru, Safitri, Amalia, Suwito, Asih, Puji B., Kosasih, Sully, Shinta, Hawley, William A., Burkot, Thomas R., Collins, Frank H., Syafruddin, Din, Lobo, Neil F.“…Trapping, using indoor and outdoor HLC, the Ifakara tent trap C, goat and human-occupied tents, resting pots and boxes, and CDC miniature light traps was conducted for 16 nights in two sites and 8 nights in a third site, using a Latin square design. …”
Publicado 2018
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29311por Lee, Sais-Beul, Hur, Yeon-Jae, Cho, Jun-Hyeon, Lee, Jong-Hee, Kim, Tae-Heon, Cho, Soo-Min, Song, You-Chun, Seo, Young-Su, Lee, Jungkwan, Kim, Tae-sung, Park, Yong-Jin, Oh, Myung-Kyu, Park, Dong-Soo“…In recent years, raising rice seedlings in seed boxes for mechanical transplanting has increased the incidence of many seedling diseases; only a few rice varieties have been reported to exhibit resistance to bakanae disease. …”
Publicado 2018
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29312por Schönecker, Sonja, Neuhofer, Christiane, Otto, Markus, Ludolph, Albert, Kassubek, Jan, Landwehrmeyer, Bernhard, Anderl-Straub, Sarah, Semler, Elisa, Diehl-Schmid, Janine, Prix, Catharina, Vollmar, Christian, Fortea, Juan, Huppertz, Hans-Jürgen, Arzberger, Thomas, Edbauer, Dieter, Feddersen, Berend, Dieterich, Marianne, Schroeter, Matthias L., Volk, Alexander E., Fließbach, Klaus, Schneider, Anja, Kornhuber, Johannes, Maler, Manuel, Prudlo, Johannes, Jahn, Holger, Boeckh-Behrens, Tobias, Danek, Adrian, Klopstock, Thomas, Levin, Johannes“…Disease severity measured by mini mental status examination (MMSE) and FTD modified Clinical Dementia Rating Scale Sum of Boxes (FTD-CDR-SOB) significantly correlated with volume reduction in the aforementioned thalamic subregions. …”
Publicado 2018
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29313por Jeffery, Hannah C., Braitch, Manjit K., Bagnall, Chris, Hodson, James, Jeffery, Louisa E., Wawman, Rebecca E., Wong, Lin Lee, Birtwistle, Jane, Bartlett, Helen, Lohse, Ansgar W., Hirschfield, Gideon M., Dyson, Jessica, Jones, David, Hubscher, Stefan G., Klenerman, Paul, Adams, David H., Oo, Ye H.“…Pretreatment liver tissues were stained for forkhead box P3‐positive (FOXP3(POS)) regulatory T cells (Tregs), clusters of differentiation (CD)56(POS) natural killer (NK) cells, and chemokine (C‐X‐C motif) ligand 10. …”
Publicado 2018
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29314por Zecena, Helma, Tveit, Daniel, Wang, Zi, Farhat, Ahmed, Panchal, Parvita, Liu, Jing, Singh, Simar J., Sanghera, Amandeep, Bainiwal, Ajay, Teo, Shuan Y., Meyskens, Frank L., Liu-Smith, Feng, Filipp, Fabian V.“…Upstream regulator analysis discovered significant perturbation in oncogenic forkhead box and hypoxia inducible factor family transcription factors. …”
Publicado 2018
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29315por Lee, Soo-Hyeon, Shin, Dong-Jun, Kim, Yoseop, Kim, Cheol-Jung, Lee, Je-Jung, Yoon, Mee Sun, Uong, Tung Nguyen Thanh, Yu, Dohyeon, Jung, Ji-Youn, Cho, Duck, Jung, Bock-Gie, Kim, Sang-Ki, Suh, Guk-Hyun“…CD3(+)CD5(dim)CD21(−) cells share more NK cell functional characteristics compared with CD3(−)CD5(−)CD21(−) cells, including the expression of T-box transcription factors (Eomes, T-bet), the production of granzyme B and interferon-γ, and the expression of NK cell-related molecular receptors such as NKG2D and NKp30. …”
Publicado 2018
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29316por Gu, Yu, Huang, Fei, Wang, Yanling, Chen, Chaojin, Wu, Shan, Zhou, Shaoli, Hei, Ziqing, Yuan, Dongdong“…RESULTS: Renal damage was progressively exacerbated in a time-dependent manner at the reperfusion stage, that was consistent with the alternation of ERS activation, including glucose regulated protein 78 (BiP/GRP78), X box-binding protein1, and C/EBP homologous protein expression. …”
Publicado 2018
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29317“…These effects were concomitant with blocked ERS and apoptosis, as evidenced by inactivation of phosphorylated inositol-requiring enzyme-1α (IRE1α)/spliced X-box binding protein 1 (XBP1), phosphorylated protein kinase-like kinase (PERK)/phosphorylated eukaryotic initiation factor 2α (eIF2α) and glucose-regulated protein 78 (GRP78)/activating transcription factor 6 (ATF6α)/C/EBP homologous protein (CHOP) pathways, as well as suppressed Bcl-2-associated X protein (BAX)/B-cell lymphoma-2 (Bcl-2) and cleaved caspase 3 expressions. …”
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29318por Ni, Jun, Shah, Faheem Afzal, Liu, Wenbo, Wang, Qiaojian, Wang, Dongdong, Zhao, Weiwei, Lu, Weili, Huang, Shengwei, Fu, Songling, Wu, Lifang“…Specifically, the gynoecium development-related genes SPATULA (SPT), KANADI 2 (KAN2), JAGGED (JAG) and Cytochrome P450 78A9 (CYP79A9) were significantly up-regulated, whereas the expression of PISTILLATA (PI), TATA Box Associated Factor II 59 (TAFII59) and MYB Domain Protein 108 (MYB108) that were important for male organ development was down-regulated in response to 6-BA treatment, demonstrating that cytokinin could directly target the floral organ identity genes to regulate the flower sex. …”
Publicado 2018
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29319por Fuller, Gordon W., Goodacre, Steve, Keating, Samuel, Perkins, Gavin, Ward, Matthew, Rosser, Andy, Gunson, Imogen, Miller, Joshua, Bradburn, Mike, Thokala, Praveen, Harris, Tim, Carson, Andrew, Marsh, Maggie, Cooper, Cindy“…Enrolled patients will be allocated (1:1 simple randomisation) to prehospital CPAP (O_two system) or standard oxygen therapy using identical sealed boxes. Feasibility outcomes will include incidence of recruited eligible patients, number of erroneously recruited patients and proportion of cases adhering to allocation schedule and treatment, followed up at 30 days and with complete data collection. …”
Publicado 2018
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29320por Liu, Chao, Sun, Bing, Xu, Bin, Meng, Xiangying, Li, Lan, Cong, Yang, Liu, Jiannan, Wang, Qian, Xuan, Liang, Song, Qibin, Wu, Shikai“…Pretreatment peripheral blood was collected and tested for mRNA expression of PD-1, cytotoxic T lymphocyte antigen 4, forkhead box P3, transforming growth factor beta, interleukin-10 (IL-10), IL-2 receptor alpha (IL-2Rα), and cluster of differentiation 28 by quantitative reverse transcription PCR. …”
Publicado 2018
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