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  1. 29361
    por Moody, Laura, Chen, Hong, Pan, Yuan-Xiang
    Publicado 2020
    “…Variability between measurement platforms makes it difficult to compare between cohorts, and large numbers of gene features have encouraged the use black box methods that are not easily translated into biologically and clinically meaningful findings. …”
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    Considerations for feature selection using gene pairs and applications in large-scale dataset integration, novel oncogene discovery, and interpretable cancer screening
  2. 29362
    “…Previously, we have shown that the exposure of mice to hyperoxia induces the release of the nuclear protein high mobility group box-1 (HMGB1) into the pulmonary airways. Furthermore, extracellular HMGB1 impairs macrophage phagocytosis and increases the mortality of mice infected with Pseudomonas aeruginosa (PA). …”
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    GTS-21, an α7nAChR agonist, increases pulmonary bacterial clearance in mice by restoring hyperoxia-compromised macrophage function
  3. 29363
    “…Transcription factor Forkhead box M1 (FOXM1), which participates in cell proliferation and cell cycle progression, has been reported to affect the sensitivity of chemotherapy. …”
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    FOXM1 modulates docetaxel resistance in prostate cancer by regulating KIF20A
  4. 29364
    “…ATP and high-mobility group box 1 (HMGB1) release were detected by luminescence and ELISA assays, respectively. …”
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    Online Artículo Texto
    Vaccination with early ferroptotic cancer cells induces efficient antitumor immunity
  5. 29365
    “…Studies on the possible relations between aging-related genes and LOA contribute to the diagnosis and treatment of LOA. Forkhead Box O3 (FOXO3) and TP53 are two classic aging-related genes. …”
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    The DNA methylation of FOXO3 and TP53 as a blood biomarker of late-onset asthma
  6. 29366
    “…The overexpression of lncRNA FTX significantly increased the expression of EMT-related protein, E-cadherin, and decreased the protein expression of vimentin, N-cadherin, and zinc finger E-box binding homeobox 1. In addition, the overexpression of lncRNA FTX could decrease the expression of p-PI3K/PI3K and p-Akt/Akt. …”
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    Role of lncRNA FTX in invasion, metastasis, and epithelial-mesenchymal transition of endometrial stromal cells caused by endometriosis by regulating the PI3K/Akt signaling pathway
  7. 29367
    por Safitri, Erma
    Publicado 2020
    “…BACKGROUND AND AIM: Octamer-binding transcription factor 4 (OCT4) and sex-determining region Y-box 2 (SOX2) are transcription factors whose functions are essential to maintain the pluripotency of embryonic stem cells. …”
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    Effect of low oxygen tension on transcriptional factor OCT4 and SOX2 expression in New Zealand rabbit bone marrow-derived mesenchymal stem cells
  8. 29368
    “…To facilitate reproducibility and avoid system dependencies, the pipeline is contained within a pre-configured VirtualBox environment. The analytical tasks and format conversions are accomplished via a set of automated scripts that enable the user to go from a set of raw data, such as fastq files, to publication-ready results and figures in one step. …”
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    Automated Isoform Diversity Detector (AIDD): a pipeline for investigating transcriptome diversity of RNA-seq data
  9. 29369
    “…(Gly84Val) in the SOX11 gene (SRY-related HMG-box gene 11). The variant had occurred de novo. …”
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    First observation of secondary childhood glaucoma in Coffin-Siris syndrome: a case report and literature review
  10. 29370
    “…MATERIALS AND METHODS: Quantitative real-time polymerase chain reaction (qRT-PCR) was conducted to detect the expression levels of PCED1B-AS1, microRNA-484 (miR-484), and zinc finger E-box binding homeobox 1 (ZEB1) in 40 pairs of human ccRCC tissues and corresponding adjacent kidney tissue samples. …”
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    Long Non-Coding RNA PCED1B-AS1 Promotes the Progression of Clear Cell Renal Cell Carcinoma Through miR-484/ZEB1 Axis
  11. 29371
    “…Statistical differences in HOMA-IR and insulin between overweight or lean cats were evaluated using Wilcoxon rank-sum test. Robust method with Box-Cox transformation was used for calculating HOMA-IR reference interval in healthy lean cats. …”
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    Homeostasis model assessment, serum insulin and their relation to body fat in cats
  12. 29372
    “…The magnitude and timing of enhancements depend on the land cover type and net fluxes surrounding each background tower, so a simple box model is not appropriate for interpretation of these data. …”
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    The influence of near-field fluxes on seasonal carbon dioxide enhancements: results from the Indianapolis Flux Experiment (INFLUX)
  13. 29373
    “…We propose one modified YOLOV4 model, called YOLOV4-MOD and two modified models of YOLOV3, which are called YOLOV3-MOD1 and YOLOV3-MOD2. Besides, new anchor box sizes are generated using K-means clustering algorithm to exploit the potential of these models in small object detection. …”
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    Malaria parasite detection in thick blood smear microscopic images using modified YOLOV3 and YOLOV4 models
  14. 29374
    “…BACKGROUND: We aimed to investigate the prevalence and prognostic role of Sex determining region Y-box 2 (SOX2) amplification and expression in surgically resected esophageal squamous cell carcinoma (ESCC). …”
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    SOX2 amplification and chromosome 3 gain significantly impact prognosis in esophageal squamous cell carcinoma
  15. 29375
    “…Nonetheless, the application of deep learning in healthcare remains limited since deep learning methods are often considered as non-interpretable black-box models. However, the machine learning community made recent elaborations on interpretability methods explaining data point-specific decisions of deep learning techniques. …”
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    Explaining decisions of graph convolutional neural networks: patient-specific molecular subnetworks responsible for metastasis prediction in breast cancer
  16. 29376
    “…Out of the total 4022 annotated genes, 3884 are protein coding, 87 are RNA encoding genes, and the remaining 51 genes were associated with regulatory features of the genome including riboswitches and T-box leader sequences. Approximately 24% of the protein coding genes were hypothetical. …”
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    Hybrid genome de novo assembly with methylome analysis of the anaerobic thermophilic subsurface bacterium Thermanaerosceptrum fracticalcis strain DRI-13(T)
  17. 29377
    “…One theory is that increased numbers of regulatory CD3(+)CD4(+)CD25(+)FOXP3(+) T cells (Tregs) and forkhead box protein-3 mRNA (FOXP3) expression in the blood after transfusion contribute to these outcomes. …”
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    Effect of intraoperative blood transfusion on Treg and FOXP3 in patients with digestive tract malignancies and different ABO blood types
  18. 29378
    “…BACKGROUND: High-mobility group box-1 protein (HMGB1) serves as the prototypic damage-associated molecular pattern molecule, and TLR4 is considered a receptor for HMGB1. …”
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    HMGB1/TLR4 Signaling Affects Regulatory T Cells in Acute Lung Injury
  19. 29379
    “…BACKGROUND: Forkhead box protein M1 (FOXM1) is an oncogene regulating tumor growth and metastasis. …”
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    Online Artículo Texto
    Expression and mechanism of exosome-mediated A FOXM1 related long noncoding RNA in gastric cancer
  20. 29380
    “…Finally, anxiety-like behaviors were assessed by elevated plus maze and black and white box tests. RESULTS: First, in situ hybridization showed DED to trigger upregulation of TRPV1, TRPA1, ASIC1, and ASIC3 mRNA in the ophthalmic branch of the TG. …”
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    Capsazepine decreases corneal pain syndrome in severe dry eye disease
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