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30261por Alsterda, Andrew, Asha, Kumari, Powrozek, Olivia, Repak, Miroslava, Goswami, Sudeshna, Dunn, Alexandra M., Memmel, Heidi C., Sharma-Walia, Neelam“…We detected remarkably high gene expression of CCAAT enhancer-binding protein homologous protein (CHOP), inositol-requiring enzyme 1 (IRE1α), protein disulfide-isomerase (PDI), PKR-like ER kinase (PERK), activating transcription factor 4 (ATF4), X-box binding protein 1 (XBP-1) and growth arrest and DNA damage-inducible protein (GADD34) in SUM149PT and SUM190PT cells when compared to HMEC. …”
Publicado 2021
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30262por Boyle, Eleanor, Folkestad, Lars, Frafjord, Erik, Koes, Bart W, Skou, Soren Thorgaard, Hartvigsen, Jan“…Individuals whose secured email box was not active at the time were discarded. Using the Central Person Registry number, a unique number assigned to all Danish residents, we linked the sample frame to different registries to learn more about non-responders. …”
Publicado 2021
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30263“…In addition, the increase in paper mulberry linearly and quadratically improved the expressions of myoblast determination protein (MyoD), myogenin (MyoG), paired box protein 7 (Pax7) and myostatin 1 (MSTN1) (p < 0.05). …”
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30264por Gómez-Cruz, Irene, Contreras, María del Mar, Carvalheiro, Florbela, Duarte, Luís C., Roseiro, Luisa B., Romero, Inmaculada, Castro, Eulogio“…Therefore, EOP was subjected to bath-type ultrasound-assisted extraction (UAE), and the effects of the acetone concentration (20–80%, v/v), solid load (2–15%, w/v), and extraction time (10–60 min) on the extraction of antioxidant compounds were evaluated according to a Box–Behnken experimental design. By means of the response surface methodology, the optimum conditions were obtained: 40% acetone, 8.6% solids, and 43 min. …”
Publicado 2021
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30265“…Most eggs were laid in the nest box and were clean. Clean eggs declined, and dirty eggs increased, significantly with age, particularly at the scratch mat (p < 0.001). …”
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30266por Liu, Xiumei, Chen, Di, Chen, Huan, Wang, Wen, Liu, Yu, Wang, Yawei, Duan, Chao, Ning, Zhen, Guo, Xin, Otkur, Wuxiyar, Liu, Jing, Qi, Huan, Liu, Xiaolong, Lin, Aifu, Xia, Tian, Liu, Hong‐xu, Piao, Hai‐long“…BACKGROUND: Y‐box binding protein 1 (YB1 or YBX1) plays a critical role in tumorigenesis and cancer progression. …”
Publicado 2021
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30267por Zhu, Qingwen, Zhang, Qicheng, Gu, Miao, Zhang, Kaiwen, Xia, Tian, Zhang, Siyu, Chen, Wenhui, Yin, Haimeng, Yao, Hui, Fan, Yue, Pan, Si, Xie, Haijing, Liu, Huiting, Cheng, Tianyi, Zhang, Panpan, Zhang, Ting, You, Bo, You, Yiwen“…Abbreviations: ACTB: actin beta; ATG: autophagy-related; ATG5: autophagy related 5; BLI: bioluminescence; BTG3: BTG anti-proliferation factor 3; CASP3: caspase 3; ChIP: chromatin immunoprecipitation; CQ: chloroquine; Ct: threshold cycle; DAPI: 4ʹ,6-diamidino-2-phenylindole; DiL: 1,1ʹ-dioctadecyl-3,3,3ʹ,3ʹ-tetramethylindocarbocyanine perchlorate; EBSS: Earle’s balanced salt solution; EGR1: early growth response 1; GAPDH: glyceraldehyde-3-phosphate dehydrogenase; GEO: Gene Expression Omnibus; GFP: green fluorescent protein; IF: immunofluorescence; IHC: immunohistochemistry; ISH: in situ hybridization; MAP1LC3B: microtubule associated protein 1 light chain 3 beta; MIR106A-5p: microRNA 106a-5p; miRNAs: microRNAs; MKI67: marker of proliferation ki-67; mRNA: messenger RNA; MTOR: mechanistic target of rapamycin kinase; NPC: nasopharyngeal carcinoma; qRT-PCR: quantitative real-time PCR; siRNA: small interfering RNA; SOX9: SRY-box transcription factor 9; SQSTM1: sequestosome 1; TCGA: The Cancer Genome Atlas; WB: western blot.…”
Publicado 2020
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30268por Evans, Caitlin E, Saensukjaroenphon, Marut, Gebhardt, Jordan T, Stark, Charles R, Paulk, Chad B“…Pellet durability index (PDI) was determined using the tumble box and Holmen NHP 100 methods. Samples of the unconditioned mash (M), conditioned mash (CM), and pellets (P) were collected and analyzed for phytase and xylanase concentration. …”
Publicado 2021
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30269por Desser, Dmitriy, Assunção, Francisca, Yan, Xiaoguang, Alves, Victor, Fernandes, Henrique M., Hummel, Thomas“…The algorithm consisted of the following four different steps: (1) multimodal data co-registration of whole-brain T1 images and T2 images, (2) template-based localization of OBs, (3) bounding box construction, and lastly, (4) segmentation of the OB using a 3D-U-Net. …”
Publicado 2021
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30270por Shah, Kanan, Sharma, Akarsh, Moulton, Chris, Swift, Simon, Mann, Clifford, Jones, Simon“…Forecasts were generated using the three most widely used automated forecasting techniques: exponential smoothing; Seasonal Autoregressive Integrated Moving Average; and Trigonometric, Box-Cox transform, autoregressive moving average errors, and Trend and Seasonal components. …”
Publicado 2021
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30271por Olech, Monika, Ropka-Molik, Katarzyna, Szmatoła, Tomasz, Piórkowska, Katarzyna, Kuźmak, Jacek“…In turn, the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway tool classified DEGs that enrich molecular processes such as B and T-cell receptor signaling pathways, natural killer cell-mediated cytotoxicity, Fc gamma R-mediated phagocytosis, toll-like receptor signaling pathways, TNF, mammalian target of rapamycin (mTOR) signaling and forkhead box O (Foxo) signaling pathways, etc. Our data indicate that changes in SRLV proviral load induced altered expression of genes related to different biological processes such as immune response, inflammation, cell locomotion, and cytokine production. …”
Publicado 2021
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30272por Leven, Anna-Sophia, Gieseler, Robert K., Schlattjan, Martin, Schreiter, Thomas, Niedergethmann, Marco, Baars, Theodor, Baba, Hideo A., Özçürümez, Mustafa K., Sowa, Jan-Peter, Canbay, Ali“…Abbreviations: ATG5: autophagy related 5; BAS: bariatric surgery; BMI: body mass index; ELISA: enzyme-linked immunosorbent assay; EtOH: ethanol; FFAs: free fatty acids; HCC: hepatocellular carcinoma; HMGB1: high-mobility group box 1 protein; IHC: immunohistochemistry; IL: interleukin; LC3: microtubule-associated proteins 1A/1B light chain 3B; M30: neoepitope K18Asp396-NE displayed on the caspase-cleaved keratin 18 fragment; M65: epitope present on both caspase-cleaved and intact keratin 18; NAFL: non-alcoholic fatty liver; NAFLD: non-alcoholic fatty liver disease; NAS: NAFLD activity score; NASH: non-alcoholic steatohepatitis; NLRP3: nucleotide-binding oligomerization domain, leucine-rich repeat and pyrin domain containing 3; qRT-PCR: quantitative real-time polymerase-chain reaction; r: Pearson’s correlation coefficient (r); r(s): Spearman’s rank correlation coefficient; RIPK3: receptor-interacting serine/threonine-protein kinase 3; T2DM: type 2 diabetes mellitus (T2DM); TUNEL: terminal deoxynucleotidyl transferase-mediated dUTP nick-end labelling; vWAT: visceral WAT; WAT: white adipose tissue…”
Publicado 2021
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30273por von Arx, Michael, Liechti, Melanie, Connolly, Lukas, Bangerter, Christian, Meier, Michael L., Schmid, Stefan“…Thirty healthy pain-free individuals were enrolled in this study and asked to repetitively lift a 15 kg-box by applying 1) a freestyle, 2) a squat and 3) a stoop lifting technique. …”
Publicado 2021
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30274“…In AI, explanations are seen as a tool to communicate the rationale behind black-box decisions to encourage trust and adoption. However, the effectiveness of the types of explanations used in AI-driven symptom checkers has not yet been studied. …”
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30275por Rogero, Ryan G., Corr, Daniel, Fisher, Andrew, O’Neil, Joseph T., Fuchs, Daniel J., Raikin, Steven M.“…Augmentation involved weaving the tendon through the Achilles above and below the rupture site creating a box type biologic augmentation. Patients were contacted at >=2 years postoperatively to complete the Foot & Ankle Ability Measure (FAAM)-Activities of Daily Living (ADL) and -Sports subscales, visual analog scale (VAS) for pain, as well as surveyed regarding their satisfaction with the surgical outcome using a 5- point Likert scale. …”
Publicado 2021
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30276por Shiels, Dwayne, Loughrey, Jason, Dwyer, Cathy M., Hanrahan, Kevin, Mee, John F., Keady, Timothy W. J.“…Lamb mortality tended to be lower (Kruskal–Wallis (KW) = 2.749; p = 0.09) on farms that used stomach tubing, heat box, iodine, hospital, and individual pens compared with farms that do not implement all those practices. …”
Publicado 2021
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30277por Ricci, Elena, Fava, Mariarosa, Rizza, Pietro, Pellegrino, Michele, Bonofiglio, Daniela, Casaburi, Ivan, Lanzino, Marilena, Giordano, Cinzia, Bruno, Rosalinda, Sirianni, Rosa, Barone, Ines, Sisci, Diego, Morelli, Catia“…Here, the role of the Forkhead box class O (FoxO)3a transcription factor in tumor progression has been evaluated in tamoxifen-resistant BC cells (TamR), expressing lower levels of FoxO3a compared to sensitive ones. …”
Publicado 2022
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30278“…Anonymous questionnaires were collected into a sealed box and analysed using Statistical Package for Social Sciences 20. …”
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30279por Tatham, Lee, Kipar, Anja, Sharp, Joanne, Kijak, Edyta, Herriott, Joanne, Neary, Megan, Box, Helen, Toledo, Eduardo Gallardo, Valentijn, Anthony, Cox, Helen, Pertinez, Henry, Curley, Paul, Arshad, Usman, Rajoli, Rajith KR, Rannard, Steve, Stewart, James, Owen, AndrewEnlace del recurso
Publicado 2023
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30280por Jiang, Hongxia, Jiang, Qianqian, He, Yuanzhou, Li, Xiaochen, Xu, Yongjian, Liu, Xiansheng“…Spliced X-box binding protein 1 (XBP1s) has been reported to participate in the pathogenesis of numerous types of cancer; however, whether XBP1s plays a role in lung cancer remains to be elucidated. …”
Publicado 2022
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