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30301por Jin, Xue Cheng, Peng, Dong Qiao, Kim, Seong Jin, Kim, Na Yeon, Nejad, Jalil Ghassemi, Kim, Danil, Smith, Stephen B., Lee, Hong Gu“…In addition, mRNA expression in longissimus dorsi muscle revealed upregulation of paired box 7 (PAX7) (P < 0.05) after the vitamin A treatment period based on biopsy results. …”
Publicado 2022
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30302por Hua, Alice, Martin, Kevin, Shen, Yuzeng, Chen, Nicole, Mou, Catherine, Sterk, Maximilian, Reinhard, Berend, Reinhard, Friedrich F., Lee, Stephen, Alibhai, Sky, Jewell, Zoe C.“…We used a YOLOv5l6 object detection architecture trained to identify a bounding box for one of five objects of interest in a frame of video. …”
Publicado 2022
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30303por Zhou, Lin, Zhao, Yang, Pan, Li-Chao, Wang, Jing, Shi, Xian-Jie, Du, Guo-Sheng, He, Qiang“…This was achieved by activation of HIF-1α and glycolysis in HCC, leading to the upregulation of LDHA, GLUT-1, Akt/mammalian target of rapamycin (mTOR), vascular endothelial growth factor (VEGF), and Forkhead box P3 and downregulation of phosphatase and tensin homolog deleted on chromosome ten (PTEN) and p27. …”
Publicado 2022
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30304“…The findings from the RPPA were validated by western blotting for representative signaling factors identified, including forkhead box M1 (FOXM1; proliferation factor), pRb (cell cycle regulator), and Smac/DIABLO (pro-apoptosis) among treatment conditions. …”
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30305por Rezaeijo, Seyed Masoud, Jafarpoor Nesheli, Shabnam, Fatan Serj, Mehdi, Tahmasebi Birgani, Mohammad Javad“…Firstly, images were registered, and cropping was performed through a bounding box. In addition to T2W, DWI, and ADC separately, fused images were used. …”
Publicado 2022
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30306por Plouff, Cherie, Byler, Caitlin, Hyatt, Melissa, Jreissaty, Claudine, Joe, Timisha, Thomas, April, Mejicanos, Jennefer, Smith, Regina, Hellstern, Braden R, Hassid, Victor J“…Patient experience scores, measured by Press Ganey®, increased annually, with 2017, 2018, 2019, and 2020 fiscal year top box scores averaging 80.6%, 83.9%, 85.9%, and 86.4%, respectively. …”
Publicado 2022
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30307por Wang, Qi, Bu, Qingfa, Liu, Mu, Zhang, Rui, Gu, Jian, Li, Lei, Zhou, Jinren, Liang, Yuan, Su, Wantong, Liu, Zheng, Wang, Mingming, Lian, Zhexiong, Lu, Ling, Zhou, Haoming“…BACKGROUND & AIMS: XBP1 modulates the macrophage proinflammatory response, but its function in macrophage stimulator of interferon genes (STING) activation and liver fibrosis is unknown. X-box binding protein 1 (XBP1) has been shown to promote macrophage nucleotide-binding oligomerization domain, leucine-rich repeat and pyrin domain-containing 3 (NLRP3) activation in steatohepatitis. …”
Publicado 2022
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30308por Zhen, Huimin, Shen, Jiyuan, Wang, Jiqing, Luo, Yuzhu, Hu, Jiang, Liu, Xiu, Li, Shaobin, Hao, Zhiyun, Li, Mingna, Shi, Bingang, Gu, Yuanhua“…The small interfering RNA of circ_003628 (named si-circ_003628) inhibited the viability and proliferation of goat SMSCs, and also decreased the expression of four cell proliferation marker genes: paired box 7 (Pax7), cyclin-dependent kinase 2 (CDK2), CDK4 and CyclinD1 in goat SMSCs. …”
Publicado 2022
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30309por Teveroni, Emanuela, Di Nicuolo, Fiorella, Vergani, Edoardo, Bianchetti, Giada, Bruno, Carmine, Maulucci, Giuseppe, De Spirito, Marco, Cenci, Tonia, Pierconti, Francesco, Gulino, Gaetano, Bassi, Pierfrancesco, Pontecorvi, Alfredo, Milardi, Domenico, Mancini, Francesca“…Our data showed a PTTG1-mediated E-CAD transcriptional repression through Zinc finger E-box binding homeobox 1 (ZEB1), a master regulator of the EMT process. …”
Publicado 2022
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30310por Gould, James, Goldstein, Judah, Travers, Andrew H, Swain, Janel M, Carter, Alix, Rollo, Derek, Mekwan, Jay, Atkinson, Paul, Kovacs, George“…Consecutive non-traumatic OHCA and emergency department (ED) cardiac arrests occurring in a pre-determined catchment area (20-minute transport to ECMO center) defined by a geographic bounding box were identified. Criteria for ECPR were developed to identify candidates for activation of a “Code ECPR”: (1) age 16-70, (2) witnessed arrest, (3) no flow duration (time to CPR, including bystander) <10 minutes, (4) resuscitation >10 minutes without return of spontaneous circulation (ROSC), (5) emergency medical service (EMS) transport to hospital <20 minutes, (6) no patient factors precluding ongoing resuscitation (do not resuscitate status (DNR), palliative care involvement, or metastatic cancer), and (7) initial rhythm not asystole. …”
Publicado 2022
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30311por Kim, Billy I., Peairs, Emily, Lander, Sarah, Antonelli, Christopher, Lau, Brian C.“…A total of 1012 patient satisfaction surveys were available and analyzed using the top-box method. Univariable statistics (t test or Mann-Whitney U and chi-square tests) were used for group comparisons. …”
Publicado 2022
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30312por Garcia, Erin, Mitsunaga, Tisha, Haridass, Vikram, Martin, Brieanne, Sardana, Neha, Franqui, Lisa, Komaiko, Kiya, Lanier, Tracy, Epson, Erin“…We will continue to provide online training and resources, access to IPC experts including an ‘AskBox’ for CNAs to e-mail IPC questions or request one-on-one support, and monthly office hours. …”
Publicado 2022
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30313por Alsaidan, Omar Awad, Zafar, Ameeduzzafar, Yasir, Mohd, Alzarea, Sami I., Alqinyah, Mohammed, Khalid, Mohammad“…The BLO was prepared by the thin-film hydration method and optimized by the Box–Behnken design. Cholesterol (CHO), surfactant (Span 60), and bile salt (sodium deoxycholate/SDC) were used as formulation factors. …”
Publicado 2022
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30314por Wu, Xiao-Bing, Wu, You-Tao, Guo, Xin-Xing, Xiang, Chun, Chen, Pei-Sheng, Qin, Wang, Shi, Zhong-Song“…The five hub genes (hypoxia-inducible factor 1 subunit alpha, estrogen receptor 1, forkhead box O1, insulin-like growth factor 1, CREB binding protein) were involved in the inflammatory response. …”
Publicado 2022
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30315Publicado 2022“…The downstream target gene of miR-367-3p was analyzed by bioinformatics. Zinc finger E-box binding homeobox 2 (ZEB2) was detected by Real-time PCR and Western blot. …”
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30316por Sitsen, Elske, Khalili-Mahani, Najmeh, de Rover, Mischa, Dahan, Albert, Niesters, Marieke“…Calibrated heat-pain stimuli were administered to the right forearm (C8-Th1) using a box-car design (blocks of 10s on/25s off) during MRI scanning. …”
Publicado 2022
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30317por Gallego-Ortega, Alejandro, Norte-Muñoz, María, Di Pierdomenico, Johnny, Avilés-Trigueros, Marcelino, de la Villa, Pedro, Valiente-Soriano, Francisco Javier, Vidal-Sanz, Manuel“…Methods: The αRGC population and its subtypes were studied in flat-mounted retinas and radial sections immunodetected against non-phosphorylated high molecular weight neurofilament subunit (SMI-32) or osteopontin (OPN), two αRGCs pan-markers; Calbindin, expressed in ONs-αRGCs, and amacrines; T-box transcription factor T-brain 2 (Tbr2), a key transcriptional regulator for ipRGC development and maintenance, expressed in ipRGCs and GABA-displaced amacrine cells; OPN4, an anti-melanopsin antibody; or Brn3a and Brn3c, markers of RGCs. …”
Publicado 2022
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30318por Aryankalayil, Molykutty J., Bylicky, Michelle A., Martello, Shannon, Chopra, Sunita, Sproull, Mary, May, Jared M., Shankardass, Aman, MacMillan, Laurel, Vanpouille-Box, Claire, Dalo, Juan, Scott, Kevin M. K., Norman Coleman, C.Enlace del recurso
Publicado 2023
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30319por Xia, Ting, Xu, Wen-Jie, Hu, Yan-Nan, Luo, Zhen-Ye, He, Wen, Liu, Chang-Shun, Tan, Xiao-Mei“…Network pharmacological analysis indicated that SMW and SMW-BI may exert hypoglycemic by regulating insulin receptor substrate 1 (IRS1)/RAC-beta serine/threonine-protein kinase (AKT2)/forkhead box protein O1 (FOXO1)/glucose transporter type 2 (GLUT2) signaling. …”
Publicado 2023
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30320por Qian, Jing, Zhang, Yiding, Betensky, Rebecca A., Hyman, Bradley T., Serrano-Pozo, Alberto“…METHODS: We analyzed APOE associations with the cognitive trajectories (Clinical Dementia Rating scale Sum of Boxes [CDR-SOB] and Mini-Mental State Examination [MMSE]) of more than 1,000 individuals from a national clinicopathologic sample who had either no, mild (sparse neuritic plaques and the Braak neurofibrillary tangle [NFT] stage I/II), or intermediate (moderate neuritic plaques and the Braak NFT stage III/IV) ADNC levels at autopsy via 2 latent classes reverse-time longitudinal modeling. …”
Publicado 2023
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