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30441por Zbytniewska, Monika, Kanzler, Christoph M., Jordan, Lisa, Salzmann, Christian, Liepert, Joachim, Lambercy, Olivier, Gassert, Roger“…Clinical feasibility (duration), reliability (intra-class correlation coefficient ICC, smallest real difference SRD) and validity (Kruskal-Wallis test, Spearman correlations [Formula: see text] with Fugl-Meyer Upper Limb Motor Assessment, kinesthetic Up-Down Test, Box & Block Test) of robotic tasks were evaluated with 36 sub-acute stroke subjects and 31 age-matched neurologically intact controls. …”
Publicado 2021
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30442por Sajjadi, Nicholas B, Shepard, Samuel, Ottwell, Ryan, Murray, Kelly, Chronister, Justin, Hartwell, Micah, Vassar, Matt“…METHODS: We searched COVID-19 vaccine terms on Google and used the “People also ask” box to obtain FAQs generated by Google’s machine learning algorithms. …”
Publicado 2021
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30443por Guo, Xiao-Jun, Lu, Jia-Cheng, Zeng, Hai-Ying, Zhou, Rong, Sun, Qi-Man, Yang, Guo-Huan, Pei, Yan-Zi, Meng, Xian-Long, Shen, Ying-Hao, Zhang, Peng-Fei, Cai, Jia-Bin, Huang, Pei-Xin, Ke, Ai-Wu, Shi, Ying-Hong, Zhou, Jian, Fan, Jia, Chen, Yi, Yang, Liu-Xiao, Shi, Guo-Ming, Huang, Xiao-Yong“…In this study, immunohistochemistry (IHC) was used to detect and quantify CTLA-4, forkhead box protein P3 (FOXP3), and PD-L1 in samples from 290 patients with ICC. …”
Publicado 2021
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30444por Wang, Qingshui, Zhong, Wenting, Deng, Lin, Lin, Qili, Lin, Youyu, Liu, Hongxia, Xu, Luyun, Lu, Lingfang, Chen, Yajuan, Huang, Jianping, Jiang, Meichen, Xiao, Han, Zhang, Jie, Li, He, Lin, Yuxiang, Song, Chuangui, Lin, Yao“…Correlation analyses revealed that SAE1 expression was positively correlated with forkhead box M1 (FOXM1) TFs and negatively correlated with SAE1 methylation site (cg14042711) level. …”
Publicado 2021
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30445por Li, Qingqin S., Vasanthakumar, Aparna, Davis, Justin W., Idler, Kenneth B., Nho, Kwangsik, Waring, Jeffrey F., Saykin , Andrew J.“…RESULTS: The rate of cognitive decline from initial DNA sampling visit to subsequent visits was estimated by the slopes of the modified Preclinical Alzheimer Cognitive Composite (mPACC; mPACC(digit) and mPACC(trailsB)) and Clinical Dementia Rating Scale Sum of Boxes (CDR-SB) plots using robust linear regression in cognitively normal (CN) participants and patients with mild cognitive impairment (MCI), respectively. …”
Publicado 2021
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30446por Muller, Camille O., Muthalib, Makii, Mottet, Denis, Perrey, Stéphane, Dray, Gérard, Delorme, Marion, Duflos, Claire, Froger, Jérôme, Xu, Binbin, Faity, Germain, Pla, Simon, Jean, Pierre, Laffont, Isabelle, Bakhti, Karima K. A.“…Secondary outcomes will include measures of UL function (Box and Block Test), impairment (Fugl Meyer Upper Extremity), compensation (Proximal Arm Non-Use), ADL (Actimetry, Barthel Index). …”
Publicado 2021
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30447por Wilson, Peter H., Rogers, Jeffrey M., Vogel, Karin, Steenbergen, Bert, McGuckian, Thomas B., Duckworth, Jonathan“…Primary motor measures, collected by a blinded assessor, were the Box and Blocks Task (BBT) and 9-Hole Pegboard Test (9HPT), and for cognition the Montreal Cognitive Assessment (MoCA). …”
Publicado 2021
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30448por Souza, Gregory E, de Souza, Flávio Henrique Batista, Aguiar dos Reis, Marconi A, Dorim, Raoni A, Cristine Oliveira Gonçalves, Elisângela C, Floriano, Ana Luiza Silva, Tavares, Bruna de Souza, de Oliveira, André Magalhães, Ribeiro, Daniela Da Guarda, de Sá, Felipe Gonçalves, Lacerda, Júlia O, Caetano, Leandra Vieira, Augusto, Ludmila Rodrigues, Santos, Maria Luiza Costa, Viana, Otávio Reis, Soares, Alef Santos, de Medeiros, Felipe Ferreira, Figuereido, Amanda Luiza Alves, Calderón, Sergio Alfredo Hidalgo, Rojas Puell, María José, Quispe Chauca, Andrea del Carmen, Almeida, Maria Cristina, de Araújo, Arthur André Martins, Rodrigues, Artur Moreira, de Sá Rodrigues, Cátia Ribeiro, Morais, Jefferson Ricardo Rodrigues, Cardoso, Larissa Ludgero Soares, Colbert Câmara, Matheus Álvaro, Lopes, Pedro Alcântara Antunes, de Resende, Mateus Augusto Mendonça, de Oliveira, João Pedro Amaral, de Souza, Pedro Henrique Gonçalves, de Souza, Izadora Serdeira, Leal, Samara Soares, Aguiar, Mariana, de Faria, Maria Luiza Brandão, Ferreira, Paula G, Rocha, Leonora de Oliveira, Montes, Fernanda Luíza Pinheiro, Rocha, Luiz Felipe Oliveira“…On the bottom half of the screen, the dialogue box allows the player to collect the patient’s medical history. …”
Publicado 2021
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30449por Wang, Huan, Wu, Wei, Han, Chunxia, Zheng, Jiaqi, Cai, Xinyu, Chang, Shimin, Shi, Junlong, Xu, Nan, Ai, Zisheng“…Shapley additive explanations and local interpretable model-agnostic explanations were used to determine the interpretability of the black box model. RESULTS: A total of 11 variables were selected for the models. …”
Publicado 2021
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30450por Baumann, Julia, Tsao, Chih-Chieh, Patkar, Shalmali, Huang, Sheng-Fu, Francia, Simona, Magnussen, Synnøve Norvoll, Gassmann, Max, Vogel, Johannes, Köster-Hegmann, Christina, Ogunshola, Omolara O.“…Mice in their home cages were exposed to either normoxia (21% O(2)) or hypoxia (8% O(2)) for 96 h in an oxygen-controlled humidified glove box. All lines were similarly responsive to hypoxic challenge and post-Cre activation showed significantly reduced HIF-1 target gene levels in the individual cells as predicted. …”
Publicado 2022
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30451por Canossi, Angelica, Iesari, Samuele, Lai, Quirino, Ciavatta, Simone, Del Beato, Tiziana, Panarese, Alessandra, Binda, Barbara, Tessitore, Alessandra, Papola, Franco, Pisani, Francesco“…The purpose of our study was to examine, in peripheral blood before and after transplantation, the expression patterns of regulatory T cell (Treg)-related genes: the forkhead box P3 (FOXP3) and the two CTLA-4 isoforms (full-length and soluble) to predict acute rejection onset, de novo donor-specific antibodies (DSA) development and renal dysfunction 1 year after transplantation. …”
Publicado 2022
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30452por Leung, Amy Wing-Sze, Leung, Henry Chi-Ming, Wong, Chak-Lim, Zheng, Zhen-Xian, Lui, Wui-Wang, Luk, Ho-Ming, Lo, Ivan Fai-Man, Luo, Ruibang, Lam, Tak-Wah“…CONCLUSION: We presented ECNano, an out-of-the-box workflow comprising (1) a wet-lab protocol for ONT target enrichment sequencing and (2) a downstream variant detection workflow, Clair-ensemble. …”
Publicado 2022
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30453por Tang, Xiaozhu, Deng, Zhendong, Ding, Pinggang, Qiang, Wanting, Lu, Yue, Gao, Shengyao, Hu, Ye, Yang, Ye, Du, Juan, Gu, Chunyan“…Due to circHNRNPU_603aa including RNA-binding RGG-box region, it regulated SKP2 exon skipping, thereby competitively inhibited c-Myc ubiquitin so as to stabilize c-Myc in MM. …”
Publicado 2022
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30454por Sun, Wenqing, Li, Yan, Ma, Dongyu, Liu, Yi, Xu, Qi, Cheng, Demin, Li, Guanru, Ni, Chunhui“…The expression of ALKBH5, miR-320a-3p, and forkhead box protein M1 (FOXM1) was determined by quantitative real-time polymerase chain reaction (qRT-PCR) analysis. …”
Publicado 2022
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30455por Liu, Wen-Shan, Chien, Ju-Chun, Huang, Yu-Hsien, Chen, Po-Chun, Huang, Wei-Lun, Chiang, Shao-Wei, Lee, Ching-Chih, Kang, Bor-Hwang, Hu, Yu-Chang“…Patients with severe (≥G3) dysphagia had significant higher mean doses of base of tongue (56.2 vs 50.2 Gy, p = 0.008), laryngeal box (50.6 vs 46.4 Gy, p = 0.036), PCM (65.4 vs 62.1 Gy, p = 0.008), SMPCM (67.1 vs 64.2 Gy, p = 0.014), and SPCM (69.3 vs 65.8 Gy, p = 0.004). …”
Publicado 2022
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30456por Rabah, Ayah, Le Boterff, Quentin, Carment, Loïc, Bendjemaa, Narjes, Térémetz, Maxime, Dupin, Lucile, Cuenca, Macarena, Mas, Jean-Louis, Krebs, Marie-Odile, Maier, Marc A., Lindberg, Påvel G.“…Task validity was evaluated in 54 healthy subjects (mean age 49 years, range: 20–78 years) by correlating tablet measures with age, clinical dexterity assessments (time taken to pick-up objects in Box and Block Test, BBT and Moberg Pick Up Test, MPUT) and with measures obtained using a finger force-sensor device. …”
Publicado 2022
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30457por Li, Chuang, Wang, Wei, Sun, Yuting, Ni, Yifan, Qin, Fang, Li, Xiaolu, Wang, Tao, Guo, Mingxiong, Sun, Guihong“…The molecular mechanism of hY4F and the RNA-binding protein Y box binding protein 1 (YBX1) was demonstrated by qRT-PCR, western blot, RNA pulldown, and rescue experiments. …”
Publicado 2022
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30458por Li, Li, Cui, Shunli, Dang, Phat, Yang, Xinlei, Wei, Xuejun, Chen, Kai, Liu, Lifeng, Chen, Charles Y.“…Three candidate genes related to F-box family proteins (Araip.E64SW, Araip.YG1LK, and Araip.JJ6RA) and one candidate gene related to PPP family proteins (Araip.YU281) may be involved in plant growth and development in this genome region. …”
Publicado 2022
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30459por van Keulen, Hilde, Voogt, Carmen, Kleinjan, Marloes, Kramer, Jeannet, Andree, Rosa, van Empelen, Pepijn“…This is important, as black boxes, or poorly described interventions, have long been a criticism of the eHealth field, and effective intervention elements across mobile health alcohol interventions are still largely unknown. …”
Publicado 2022
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30460por Yao, Jingyue, Wang, Jubo, Xu, Ye, Guo, Qinglong, Sun, Yuening, Liu, Jian, Li, Sichan, Guo, Yongjian, Wei, Libin“…Abbreviations: BNIP3: BCL2 interacting protein 3; CCCP: carbonyl cyanide p-trichloromethoxy-phenylhydrazone; CDK9: cyclin dependent kinase 9; CHX: cycloheximide; CQ, chloroquine; DFP: deferiprone; DOX: doxorubicin; EBSS: Earle’s balanced salt solution; E64d: aloxistatin; FOXO3: forkhead box O3; HCC: hepatocellular carcinoma; HepG2/ADR: adriamycin-resistant HepG2 cells; MMP: mitochondrial membrane potential; mito-Keima: mitochondria-targeted and pH-sensitive fluorescent protein; MitoSOX: mitochondrial reactive oxygen species; OA: oroxylin A; PB: phosphate buffer; PDX: patient-derived tumor xenograft; PINK1: PTEN induced kinase 1; POLR2A: RNA polymerase II subunit A; p-POLR2A-S2: Ser2 phosphorylation of RNA polymerase II subunit A; PRKN: parkin RBR E3 ubiquitin protein ligase; SIRT1: sirtuin 1.…”
Publicado 2021
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