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30681por Laios, Alexandros, Kalampokis, Evangelos, Johnson, Racheal, Munot, Sarika, Thangavelu, Amudha, Hutson, Richard, Broadhead, Tim, Theophilou, Georgios, Leach, Chris, Nugent, David, De Jong, Diederick“…However, AI applications are encountered with several challenges derived from their “black-box” nature, which limits their adoption by clinicians. …”
Publicado 2022
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30682“…Motor function was assessed using the Assisting Hand Assessment (AHA) and the Box and Blocks test in affected (BBTA) and unaffected (BBTU) hands. …”
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30683por Liu, Mengying, Jia, Lei, Li, Hanping, Liu, Yongjian, Han, Jingwan, Wang, Xiaolin, Li, Tianyi, Li, Jingyun, Zhang, Bohan, Zhai, Xiuli, Yu, Changyuan, Li, Lin“…Subsequent mutation experiments revealed that the increased transcriptional activity was induced by the TATA box and the two p53 binding sites within the section. …”
Publicado 2022
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30684por Ostrowitzki, Susanne, Bittner, Tobias, Sink, Kaycee M., Mackey, Howard, Rabe, Christina, Honig, Lawrence S., Cassetta, Emanuele, Woodward, Michael, Boada, Mercè, van Dyck, Christopher H., Grimmer, Timo, Selkoe, Dennis J., Schneider, Andres, Blondeau, Kathleen, Hu, Nan, Quartino, Angelica, Clayton, David, Dolton, Michael, Dang, Yifan, Ostaszewski, Beth, Sanabria-Bohórquez, Sandra M., Rabbia, Michael, Toth, Balazs, Eichenlaub, Udo, Smith, Jillian, Honigberg, Lee A., Doody, Rachelle S.“…MAIN OUTCOMES AND MEASURES: The primary outcome was change from baseline to week 105 in Clinical Dementia Rating–Sum of Boxes (CDR-SB) score. RESULTS: There were 813 participants in CREAD (mean [SD] age, 70.7 [8.2] years; 483 female and 330 male) and 806 in CREAD2 (mean [SD] age, 70.9 [7.7] years; 456 female and 350 male). …”
Publicado 2022
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30685“…Metreleptin has a black box warning for risk of T-cell lymphoma, which has been reported in acquired generalized lipodystrophy patients, both treated and untreated with metreleptin. …”
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30686por Akalestou, Elina, Andrisse, Stanley, Johnson, Brett, Miras, Alexander Dimitri, O’Donnell, Karen, Samarasinghe, Suhaniya“…Briefly, insulin activates insulin receptor (IR) which leads to activation of phospho-AKT which increases phosphorylated forkhead box 01 (p-FOXO1, gluconeogenesis regulation) and transcriptionally regulates acetyl co-A carboxylase (ACC, de novo lipogenesis (DNL) regulation). …”
Publicado 2022
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30687por Di Ieva, Antonio, Lewis, David, Preda, Veronica Angela, Rodriguez, Michael, Volpato, Gavin“…INTRODUCTION: Silent corticotroph adenomas (SCA) are characterised by an absence of cortisol excess yet show positive immunostaining for T-Box transcription factor (TPIT) and frequently adrenocorticotropic hormone (ACTH). …”
Publicado 2022
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30688por Faulkner, Patricia, Ahmad, Irshad, Kothmann, Kadden, Laffitte, Emily, Chau, Laura, Grizzaffi, Matthew, Acebo, Sarah, Hernandez, Daniel, Skenandore, Cassandra, Browning, Luke, Newell-Fugate, Annie“…Adipocyte protein was western blotted for Total AKT and p-AKTSer473 and normalized to GAPDH. qPCR was performed to quantify insulin receptor (Insr), insulin receptor substrate 1 (Irs1), protein kinase B isoform 2 (Akt2), fork head box protein 1 (Foxo1) using the housekeeping gene Gapdh. 48-hour steroid treatments of E2 reduced pAKTSer473: AKT compared with that of controls in male vWAT. …”
Publicado 2022
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30689por Belen Apak, Fatma Burcu, Yuce, Gulbahar, Topcu, Deniz Ilhan, Gultekingil, Ayse, Felek, Yunus Emre, Sencelikel, Tugce“…The parameters analyzed were danger signal molecule (High molecular weight group box protein-1/HMGBP-1), platelet count, prothrombin time (PT), activated partial thromboplastin time (aPTT), D-dimer, fibrinogen, endothelial protein C receptor (EPCR), soluble E-selectin, soluble P-selectin, thrombomodulin, tissue plasminogen activator (TPA), plasminogen activator inhibitor-1 (PAI-1), soluble fibrin monomer complex (SFMC), platelet-derived microparticles (PDMP), β-thromboglobulin, antithrombin and protein C. …”
Publicado 2023
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30690por Brevini, Teresa, Maes, Mailis, Webb, Gwilym J., John, Binu V., Fuchs, Claudia D., Buescher, Gustav, Wang, Lu, Griffiths, Chelsea, Brown, Marnie L., Scott, William E., Pereyra-Gerber, Pehuén, Gelson, William T. H., Brown, Stephanie, Dillon, Scott, Muraro, Daniele, Sharp, Jo, Neary, Megan, Box, Helen, Tatham, Lee, Stewart, James, Curley, Paul, Pertinez, Henry, Forrest, Sally, Mlcochova, Petra, Varankar, Sagar S., Darvish-Damavandi, Mahnaz, Mulcahy, Victoria L., Kuc, Rhoda E., Williams, Thomas L., Heslop, James A., Rossetti, Davide, Tysoe, Olivia C., Galanakis, Vasileios, Vila-Gonzalez, Marta, Crozier, Thomas W. M., Bargehr, Johannes, Sinha, Sanjay, Upponi, Sara S., Fear, Corrina, Swift, Lisa, Saeb-Parsy, Kourosh, Davies, Susan E., Wester, Axel, Hagström, Hannes, Melum, Espen, Clements, Darran, Humphreys, Peter, Herriott, Jo, Kijak, Edyta, Cox, Helen, Bramwell, Chloe, Valentijn, Anthony, Illingworth, Christopher J. R., Dahman, Bassam, Bastaich, Dustin R., Ferreira, Raphaella D., Marjot, Thomas, Barnes, Eleanor, Moon, Andrew M., Barritt, Alfred S., Gupta, Ravindra K., Baker, Stephen, Davenport, Anthony P., Corbett, Gareth, Gorgoulis, Vassilis G., Buczacki, Simon J. A., Lee, Joo-Hyeon, Matheson, Nicholas J., Trauner, Michael, Fisher, Andrew J., Gibbs, Paul, Butler, Andrew J., Watson, Christopher J. E., Mells, George F., Dougan, Gordon, Owen, Andrew, Lohse, Ansgar W., Vallier, Ludovic, Sampaziotis, FotiosEnlace del recurso
Publicado 2022
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30691por Zhao, A Y, Gimpaya, N, Lisondra, J, Fujiyoshi, R, Fujiyoshi, Y, Khan, R, Tham, D, Scaffidi, M A, Bansal, R, Walsh, C, Grover, S C“…PLEASE ACKNOWLEDGE ALL FUNDING AGENCIES BY CHECKING THE APPLICABLE BOXES BELOW: None DISCLOSURE OF INTEREST: A. Zhao: None Declared, N. …”
Publicado 2023
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30692por St-Pierre, J, Rosentreter, R, Kiraly, A, Hart Szostakiwskyj, J, Novak, K, Panaccione, R, Kaplan, G, Devlin, S, Seow, C, Ingram, R, Ma, C, Wilson, S, Medellin, A, Lu, C“…PLEASE ACKNOWLEDGE ALL FUNDING AGENCIES BY CHECKING THE APPLICABLE BOXES BELOW: None DISCLOSURE OF INTEREST: None Declared…”
Publicado 2023
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30693“…PLEASE ACKNOWLEDGE ALL FUNDING AGENCIES BY CHECKING THE APPLICABLE BOXES BELOW: None DISCLOSURE OF INTEREST: D. Veldhuijzen van Zanten Shareholder of: N/A, Consultant of: N/A, Employee of: N/A, Paid Instructor of: N/A, Speakers bureau of: N/A, L. …”
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30694“…PLEASE ACKNOWLEDGE ALL FUNDING AGENCIES BY CHECKING THE APPLICABLE BOXES BELOW: None DISCLOSURE OF INTEREST: None Declared…”
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30695“…PLEASE ACKNOWLEDGE ALL FUNDING AGENCIES BY CHECKING THE APPLICABLE BOXES BELOW: None DISCLOSURE OF INTEREST: None Declared…”
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30696“…PLEASE ACKNOWLEDGE ALL FUNDING AGENCIES BY CHECKING THE APPLICABLE BOXES BELOW: None DISCLOSURE OF INTEREST: G. Postill: None Declared, E. …”
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30697por Kablawi, D, Tadjo, T F, Milic, J, Elgretli, W, Gioè, C, Lebouché, B, Cascio, A, Guraldo, G, Mazzola, G, Sebastiani, G“…PLEASE ACKNOWLEDGE ALL FUNDING AGENCIES BY CHECKING THE APPLICABLE BOXES BELOW: None DISCLOSURE OF INTEREST: None Declared…”
Publicado 2023
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30698por Rahmani, S, Caminero, A, Hann, A, Galipeau, H J, Anderson, R P, Chirdo, F, Didar, T F, Verdu, E F“…PLEASE ACKNOWLEDGE ALL FUNDING AGENCIES BY CHECKING THE APPLICABLE BOXES BELOW: CIHR, Other PLEASE INDICATE YOUR SOURCE OF FUNDING; Canadian Celiac Disease Association (CCA) DISCLOSURE OF INTEREST: None Declared…”
Publicado 2023
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30699por Fujiyoshi, M R A, Fujiyoshi, Y, Gimpaya, N, Bechara, R, Jeyalingam, T, Calo, N C, Forbes, N, Khan, R, Atalla, M, Toshimori, A, Shimamura, Y, Tanabe, M, Mosko, J, Inoue, H, Grover, S“…PLEASE ACKNOWLEDGE ALL FUNDING AGENCIES BY CHECKING THE APPLICABLE BOXES BELOW: CAG DISCLOSURE OF INTEREST: M. R. A. …”
Publicado 2023
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30700por Degro, C E, Jiménez-Vargas, N N, Schincariol, H M, Tsang, Q K, Guzman-Rodriguez, M, Lomax, A E, Reed, D E, Stein, C, Bunnett, N W, Vanner, S J“…PLEASE ACKNOWLEDGE ALL FUNDING AGENCIES BY CHECKING THE APPLICABLE BOXES BELOW: CCC DISCLOSURE OF INTEREST: None Declared…”
Publicado 2023
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