“…The expression of autophagy- and senescence-associated proteins in MSCs and silent information regulator 1 (SIRT1) and forkhead box class O 3a (FoxO3a) were analysed by western blotting. …”
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“…When the sequences of eight genes whose expression was downregulated and four genes whose expression was upregulated were compared, SKIP14, an F-box protein whose sequence is 85% homologous to that of SLY1 in Arabidopsis, presented an amino acid change (from Ser to Asn) and was expressed at a lower level in the stems of the ftdm mutant compared with the WT. …”
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“…OBJECTIVE: This study aimed to explore the correlation between the SRY-related high-mobility-group box gene 4 (SOX4) 3′ untranslated region (UTR) single nucleotide polymorphism (SNP) and osteoporosis susceptibility. …”
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“…BACKGROUND: lncRNA-CDKN2B antisense RNA 1 (ANRIL) and SRY-box transcription factor 9 (SOX9) has abnormal expression in many tumors including glioma, but the underlying molecular mechanism is unclear. …”
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“…MiR-183-5p knockdown partially abrogated the protective effects of Hemin-MSC-EXO in attenuating mitochondrial fission and cellular senescence of cardiomyocytes induced by SD/H. High mobility group box-1 (HMGB1) abundance was lower in Hemin-MSC-EXO-treated than MSC-EXO-treated mouse hearts, and HMGB1 was identified as one of the potential target genes of miR-183-5p. …”
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“…The levels of ATP-binding cassette (ABC) superfamily G member 2 (ABCG2), c-Myc, B cell-specific Moloney murine leukemia virus integration site 1 (Bmi1), and SRY-box transcription factor 2 (Sox2) were repressed by the depletion of circNOLC1 in the cells. …”
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“…Western blot discovered circCRIM1 positively affected the expression of zinc finger E-box binding homeobox 2 (ZEB2). Rescue experiments found miR-383-5p mimics reversed ZEB2 expression and the cancer-promoting effects of circCRIM1. …”
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“…Recently, we genetically modified MSCs with high mobility group box 1 (HMGB1), and these cells demonstrated high mobility by efficient migrating and homing to target neointima. …”
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“…The expression levels of TLR4, high mobility group box 1 (HMGB1), and myeloid differentiation factor 88 (MYD88) were studied using western blotting. …”
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“…FHL2-knockdown led to enhanced activation of forkhead box protein O1 (FOXO1) and its downstream genes such as Mafa and Pdx1 (encoding pancreatic and duodenal homeobox 1), as well as increased glucose uptake. …”
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“…However, the selected features by the algorithm is black box. Identifying features associated with mortality is essential to recognize characteristics of patients with high risk for better patient management. …”
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“…Tumor immune microenvironmental markers, including PD‐1 ligand (PD‐L1), CD8, CD68, CD4 and forkhead box P3, were assessed using multiplex immunofluorescence (mIF) assays. …”
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“…Cortisol did not mediate the association between baseline NPI-Q and changes in clinical dementia rating sum of boxes over 36 months. CONCLUSION: Higher CSF cortisol may reflect or contribute to more severe neuropsychiatric symptoms at baseline, as well as more pronounced worsening over 3 years, independently of the presence of AD pathology. …”
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“…However, AI is limited by its black-box nature. Therefore, a factor hindering the broad clinical application of DL in AF is the lack of assurance that the DL model is using physiological relevant features when making its prediction. …”
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“…PCA and Que down-regulated protein abundance of total receptor interacting protein kinase 1 (t-RIP1), phosphorylated-RIP1 (p-RIP1), p-RIP1/t-RIP1, t-RIP3, p-RIP3, mixed lineage kinase domain-like protein (MLKL), p-MLKL, dynamin- related protein 1 (DRP1), phosphoglycerate mutase 5 (PGAM5) and high mobility group box 1 (HMGB1) (P < 0.05) after ETEC infection. Moreover, PCA and Que reduced protein abundance of nod-like receptor protein 3 (NLRP3), nod-like receptors family CARD domain-containing protein 4 (NLRC4), apoptosis-associated speck-like protein containing a CARD (ASC), gasdermin D (GSDMD) and caspase-1 (P < 0.05) after ETEC infection. …”
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“…</strong></p> <p>If you have any questions during the webinar please don't hesitate to type them in the Q and A box.&nbsp;They will be answered after the speaker has finished the talk. …”
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“…Three different Monte-Carlo (MC) event generation programmes are employed: the PowhegBox programme at NLO QCD accuracy with the VBS approximation, the Sherpa programme in a LO multi-jet merged setup with up to three jets in the matrix-element, and the MadGraph5_aMC@NLO programme at LO accuracy. …”
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“…<P>The simplest solution would be to send the analog signals outside the sensitive area immediately after a preamplification; unfortunately, the ratio between the number of channels (around 200 000) and the space available is so high that the simple solution of sending all the SDD anodes output outside teh detector zone after a low-noise amplification is not practically manageable.Abstract:<P>The adopted solution is based on three main units:<BR>(i) A front-end chip that performs low noise amplification, fast analog storage and A/D conversion<BR>(ii) A multi-event digital buffer for data derandomization<BR>(iii) A data compression/zero suppression and system control board<P>The first two units are distributed on the ladders near the detectors and have stringent power and space requirements, while the third unit is placed at both ends of the ladders and in boxes placed on both ends of the TPC detector.<P>The first unit is the most critical part of the system. …”
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“…In order to design and tune PID controllers, many techniques are in use; the approach followed in this thesis is that of black-box modeling: the system is modeled in the time domain, a transfer function is inferred and a controller is designed. …”
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