“…Patients were assigned by selecting a numbered treatment pack from a box containing eight packs that were identical apart from the pack number. …”
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“…In participants with probable DLB, higher baseline PiB SUVR and change in PiB SUVR were associated with more rapid clinical decline, as measured by the Clinical Dementia Rating, sum of boxes (baseline PiB SUVR: regression coefficient [SE], 1.90 [0.63]; P = .005; R(2) = 0.215; change in PiB SUVR, regression coefficient [SE], 16.17 [7.47]; P = .04; R(2) = 0.124) and the Auditory Verbal Learning Test, delayed recall (baseline PiB SUVR, regression coefficient [SE], −2.09 [0.95]; P = .04; R(2) = 0.182; change in PiB SUVR, regression coefficient [SE], −25.05 [10.04]; P = .02; R(2) = 0.221). …”
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“…Leptin has been implicated in the modulation of female reproduction in vertebrate animals. Forkhead box L2 (FOXL2) and R-spondin1 (RSPO1) have also been implicated in the regulation of ovarian functions and the development of follicles. …”
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“…Abbreviations : ACTB: actin beta; ATF6: activating transcription factor 6; BECN1: beclin 1; BFL: bafilomycin A(1); CASP12: caspase 12; CASP3: caspase 3; DAPI: 4ʹ,6-diamidino-2-phenylindole; DDIT3: DNA-damage inducible transcript 3; EIF2AK3/PERK: eukaryotic translation initiation factor 2 alpha kinase 3; ER: endoplasmic reticulum; ERS: endoplasmic reticulum stress; ERN1/IRE1: endoplasmic reticulum to nucleus signaling 1; FFSS: flow fluid shear stress; HSPA5/GRP78/BiP: heat shock protein 5; LAMP2: lysosome-associated membrane protein 2; MAP1LC3B/LC3B: microtubule associated protein 1 light chain 3 beta; MTOR: mechanistic target of rapamycin kinase; MTORC1: mechanistic target of rapamycin complex 1; OA: osteoarthritis; PRKAA1/2/AMPK1/2: protein kinase, AMP-activated, alpha 1/2 catalytic subunit; RPS6: ribosomal protein S6; Rapa: rapamycin; SQSTM1/p62: sequestosome 1; TEM: transmission electron microscopy; TG: thapsigargin; TMJ: temporomandibular joints; TSC1/2: tuberous sclerosis complex 1/2; UAC: unilateral anterior crossbite; UPR: unfolded protein response; XBP1: x-box binding protein 1.…”
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“…EC number  3.6.4.12 Systematic name  ATP phosphohydrolase (DNA helix unwinding) Recommended name  DNA helicase Synonyms  3’ to 5’ DNA helicase <28> [35]  3’-5’ DNA helicase <11> [55]  3’-5’ PfDH <11> [55]  5’ to 3’ DNA helicase <26,27> [19,42]  AvDH1 <47> [37]  BACH1 helicase <19> [34]  BLM <3> [28]  BLM protein <3> [28]  BRCA1-associated C-terminal helicase <19> [34]  BcMCM <8> [52]  CeWRN-1 <43> [9]  DDX25 <3,48> [36]  DNA helicase 120 <7> [15]  DNA helicase A <4> [8]  DNA helicase E <5> [44]  DNA helicase II <9> [7]  DNA helicase III <4> [27]  DNA helicase RECQL5β <44> [17]  DNA helicase VI <3> [45]  Dbp9p <46> (<46> a member of the DEAD box protein family [24]) [24]  DmRECQ5 <1> [50]  DnaB helicase <29> [23]  E1 helicase <17> [58]  GRTH/DDX25 <3,48> [36]  HCoV SF1 helicase <23> [3]  HCoV helicase <23> [3]  HDH IV <3> [45]  Hel E <5> [44]  Hmi1p <40> [60]  MCM helicase <6,5,38> [43,54]  MCM protein <6,35> [43]  MER3 helicase <22> [30]  MER3 protein <22> [30]  MPH1 <28> [35]  NS3 <12,50> (<12,50> ambiguous [38,65,66]) [38,65,66]  NS3 NTPase/helicase <14> (<14> ambiguous [67]) [67]  NS3 protein <12> (<12> ambiguous [63]) [63]  NTPase/helicase <12,16> (<12> ambiguous [61]) [61,64]  PDH120 <7> [15]  PIF1 <33> [51]  PIF1 helicase <33> [51,53]  PcrA <37> [20]  PcrA helicase <37,41,49> [20,21,39]  PcrASpn <41> [21]  PfDH A <11> [55]  Pfh1p <27> [42]  RECQ5 <1> [49,50]  RECQ5 helicase <1> (<1> small isoform [49]) [49]  RECQL5b <44> [17]  REcQ <31> [13]  RSF1010 RepA <30> [5]  RecG <45> [6]  RecQ helicase <32> [56]  RecQsim <32> [56]  Rep52 <24> [40]  Rrm3p <26> [19]  Sgs1 <36> [29]  Sgs1 DNA helicase <36> [29]  TWINKLE <21> [33]  Tth UvrD <20> [16]  UvrD <20,42> [16,22]  UvrD helicase <39> [18]  WRN <18> [31]  WRN RecQ helicase <18> [12]  WRN helicase <18> [12]  WRN protein <18> [12]  WRN-1 RecQ helicase <43> [9]  Werner Syndrome helicase <18> [31]  Werner syndrome RecQ helicase <18> [12]  dheI I <1> [46]  dnaB <29> [23]  hPif1 <33> [53]  helicase DnaB <2> [10]  helicase II <25> [25]  helicase PcrA <49> [39]  helicase UvrD <20> [16]  helicase domain of bacteriophage T7 gene 4 protein <10> [47]  non structural protein 3 <12> (<12> ambiguous [61,62]) [61,62]  nonstructural protein 3 <12,14,50,51> (<12,14,50> ambiguous [38,63,65,66,67]; <51> ambigous [4]) [4,38,63,65,66,67]  protein NS3 <12> (<12> ambiguous [62]) [62]  scHelI <4> [26]  urvD <25> [25]…”
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“…The cockerels were housed in mobile boxes on the pasture herbage from the 50th to 77th day of age (stocking density: 0.108 m(2)/bird). …”
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“…He was inadvertently taking two Glipizide tablets twice a day as the VNA had mistakenly used these pills to fill his pill box. This serious error in confirming the patient’s medications resulted in his severe hypoglycemia. …”
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“…We also found associations between four of the identified stemness genes, Gap Junction Protein Alpha 1 (GJA1), CD24, Epithelial Adhesion Molecule (EPCAM) and SRY-related HMG-box gene 9 (SOX9), and a worse TNBC patient outcome. …”
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“…In this perspective, the silence on the phone takes on a different tone; silence reveals itself to be a source of greater anxiety than in presence: the presence of bodies, of its movements perceptible as imperceptible, of a gesture that carries or accompanies the senses, breathing, the visual context of the office and of its “decor”, represent as many essential elements in the usual capacity of the frame; in the absence of these basic sensory elements, silence can be experienced as a void, or even a gap in the bond, opening Pandora's box of paranoid fantasies acting unconsciously. …”
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“…We summarized trustworthiness using the median and IQR, and we used box-and-whisker plots to visually compare trustworthiness by slant and domain type. …”
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“…Results for subsequent overexpression studies showed that this process occurs through the regulation of E2A, a TATA box protein. CONCLUSIONS: Id3 regulates TGFβ-driven differentiation of h-CSFs and formation of h-CMFs in vitro. …”
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“…Two novel genes on chromosome 8 including the ABI/VP1 transcription factor and retinoblastoma-related protein (RBR), and 3 novel genes on chromosome 11 including a Lox, F-box and Na(+)/H(+) antiporter, were also identified. …”
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“…BACKGROUND: Forkhead box C1 (FOXC1), as a member of the FOX family, is important for promote HCC invasion and metastasis. …”
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“…Furthermore, little is known about the process of linking model output and clinical decisions due to the black-box nature of neural network models. OBJECTIVE: We aimed to present an externally validated recurrent neural network (RNN)–based continuous prediction model for in-hospital AKI and show applicable model interpretations in relation to clinical decision support. …”
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“…Abbreviations: ADK: adenosine kinase; AMPK: AMP-activated protein kinase; ATF4: activating transcription factor 4; BECN1: beclin-1; DDIT3/CHOP: DNA damage inducible transcript 3; EIF2AK3/PERK: eukaryotic translation initiation factor 2 alpha kinase 3; EIF2S1/eIF2α: eukaryotic translation initiation factor 2 subunit alpha; ER: endoplasmic reticulum; ERN1/IRE1α: endoplasmic reticulum to nucleus signaling 1; FDA: Food and Drug Administration; GSH: glutathione; HD: Huntington disease; HSPA5/GRP78: heat shock protein family A (Hsp70) member 5; HTT: huntingtin; JAK: Janus kinase, MAP1LC3B/LC3: microtubule associated protein 1 light chain 3 beta; MAP2K/MEK: mitogen-activated protein kinase kinase; MAP3K8/Tpl2: mitogen-activated protein kinase kinase kinase 8; MAPK: mitogen-activated protein kinase; MPP(+): 1-methyl-4-phenylpyridinium; MTOR: mechanistic target of rapamycin kinase; MTORC: MTOR complex; NAC: N-acetylcysteine; NGF: nerve growth factor 2; NMDA: N-methyl-D-aspartate; PCA: principal component analysis; PD: Parkinson disease; PDA: pancreatic ductal adenocarcinoma; PIK3C3: phosphatidylinositol 3-kinase catalytic subunit type 3; PMA: phorbol 12-myristate 13-acetate; PRKC/PKC: protein kinase C; ROCK: Rho-associated coiled-coil protein kinase; RR: ribonucleotide reductase; SIGMAR1: sigma non-opioid intracellular receptor 1; SQSTM1/p62: sequestosome 1; STK11/LKB1: serine/threonine kinase 11; TFEB: Transcription factor EB; TGFB/TGF-β: Transforming growth factor beta; ULK1: unc-51 like autophagy activating kinase 1; XBP1: X-box binding protein 1.…”
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“…The age of onset of vestibular dysfunction was determined both with categorical (onset in decades using Box & Whisker plots) and numeric approach (onset in years using regression analysis). …”
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“…The expression of glucose-regulated protein (GRP)78, activating transcription factor (ATF)6, X-box binding protein (XBP)1, protein kinase–like ER kinase (PERK), phosphorylated (p)-PERK, Bax, Bcl2, C/EBP homologous protein (CHOP), caspase 12, caspase 8, and caspase 3 were detected by western blot, and terminal deoxynucleotidyl transferase dUTP Nick end labeling (TUNEL) was used to determine the cardiomyocyte apoptosis index. …”
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“…Cultured supernatants were harvested after exposure to OGD for analysis of DAMP secretions, including high-mobility group box 1 (HMGB1), heat shock protein 70 (HSP70), and CIRBP, and cytotoxicity was assessed by lactate dehydrogenase releases after exposure to OGD and reperfusion. …”
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“…In terms of the possible mechanisms of treatment of OP, IFP exerts anti-OP effects in animal models probably through osteoprotegerin/receptor activator of the nuclear factor-κB ligand/receptor activator of nuclear factor-κB (OPG/RANKL/RANK), peroxisome proliferator activated receptor γ (PPAR-γ)/Axin2/Wnt, antioxidative stress via forkhead box O3a (FoxO3a)/Axin2/Wnt, phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin (PI3K/Akt/mTOR), estrogen-like effect, and gamma-aminobutyric acid/gamma-aminobutyric acid receptor (GABA/GABA(B)RI) signaling pathway. …”
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“…Breakdown of the 30 patients during the 4 week follow up period [Image: see text] Abbreviations: HCT: Hematopoietic cell transplantation; CMV: Cytomegalovirus; TCIP: T cell immunity panel Figure 2. Box-plot of percentage of CD4+ CMV specific interferon producing cells over time. …”
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