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30821por Hsieh, Yu-Tung, Chou, Yu-Chi, Kuo, Pin-Yu, Tsai, Hung-Wen, Yen, Yi-Ting, Shiau, Ai-Li, Wang, Chrong-Reen“…RESULTS: In DAH patients, there were down-regulated miR-146a levels with increased TRAF6 expression and PMA/LPS-induced NETosis in PBNs, and down-regulated miR-146a levels with increased TRAF6, high-mobility group box 1 (HMGB1), IL-8, NETs and apoptosis expression in lung tissues. …”
Publicado 2022
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30822Publicado 2002“….\\ The floors are connected to a sea bottom unit, containing the anchor, the junction box/fan-out for the electro-optical cable from shore and a number of environmental monitoring packages.\\ All electrical and optical connections between the floors and the sea bottom unit are made in the air at the sea surface at the time of deployment. …”
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30823por Sood, G“…A lead converter of thickness 3 radiation length is used to produce pre-showers. 28 box modules were placed directly behind the converter. …”
Publicado 2002
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30824por Pagliarin, Luis Gustavo, de Oliveira, Lucca Miketen, dos Anjos, Valentina Nunes Fontoura, de Souza, Cristiano de Bem Torquato, Peiter, Gabrielle Caroline, Façanha Wendel, Cinthia, Dillmann Groto, Anderson, Freire de Melo, Fabrício, Teixeira, Kádima Nayara“…Ions, peptides, water molecules, and other ones were removed from each ligand, and then, hydrogen atoms were added to the structures. The grid box was delimited and calculated using the same software ADT. …”
Publicado 2023
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30825“…There were 5 major events on 4 calendar days in 2007 regarding safety concerns related to rosiglitazone in certain patients: (1) the May 21, 2007, online release of the rosiglitazone meta-analysis performed by Nissen and Wolski and the FDA safety warning on the same day; (2) the July 30, 2007, conclusion of an FDA advisory committee meeting that rosiglitazone increased cardiac ischemic risk; (3) the August 14, 2007, update of thiazolidinedione (TZD) labels with a black-box warning for heart failure; and (4) the November 14, 2007, update to the warnings and precautions section of the rosiglitazone label for coadministration of nitrate or insulin. …”
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30826por Rahmi, Eldiza Puji, Jamal, Jamia Azdina, Kumolosasi, Endang, Jalil, Juriyati, Aladdin, Nor-Ashila“…[Image: see text] Abbreviations used: BSA: Bovine serum albumin, COX-2: Cyclooxygenase-2, CPM: Count per minute, DAMP: Danger-associated molecular pattern, DCM: Dichloromethane, DMSO: Dimethyl sulfoxide, ELISA: Enzyme-linked immunosorbent assay, FBS: Fetal bovine serum, H(2)O: Water, HEPES: 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid, HMC-1: Human mast cell-1, HMGB1: High-mobility group box 1, ICAM: Intercellular adhesion molecule, IFN: Interferon, IgG: Immunoglobulin G, IKK: IkB kinase, IL: Interleukin, iNOS: Inducible nitric oxide synthase, LPS: Lipopolysaccharide, MeOH: Methanol, MPA: Marantodes pumilum var. alata, MPL: Marantodes pumilum var. lanceolata, MPP: Marantodes pumilum var. pumila, MSU: Monosodium urate, MTT: Methylthiazole tetrazolium, NF-κB: Nuclear factor-kappa B, NLR: NOD-like receptor, NLRP3: NLR family pyrin domain containing protein 3, NO: Nitric oxide, NOD: Nucleotide-binding oligomerization domain, NSAID: Nonsteroidal anti-inflammatory drug, PAMP: Pathogen-associated molecular pattern, PBMC: Peripheral blood mononuclear cell, PBS: Phosphate buffered saline, PGE(2): Prostaglandin E(2,) PMACI: Phorbol-12-myristate 13-acetate and calcium ionosphere A23187, PRR: Pathogen recognition receptor, PTFE: Polytetrafluoroethylene, RIA: Radioimmunoassay, RIG: Retinoic acid-inducible gene I, RLR: RIG I-like receptor, RP-HPLC: Reversed-phase high-performance liquid chromatography, RPMI-1640: Roswell Park Memorial Institute-1640, TLR: Toll-like receptor, TNF: Tumor necrosis factor, VCAM: Vascular cell adhesion molecule.…”
Publicado 2017
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30827por Carbone, David, Sharpnack, Michael, He, Kai, Butterfield, Lisa H., Eggermont, Alexander M. M., Gonzalez-Cao, Maria, Karachaliou, Niki, Crespo, Guillermo, Aldeguer, Erika, Drozdowskyj, Ana, Giménez-Capitán, Ana, Teixidó, Cristina, Molina-Vila, Miguel Angel, Ramírez, Santiago Viteri, Algarra, Salvador Martin, Pérez-Ruiz, Elisabeth, Márquez-Rodas, Iván, Rodriguez-Abreu, Delvys, Blanco, Remei, Puértolas, Teresa, Royo, Maria Angeles, Rosell, Rafael, Ascierto, Maria Libera, Hamm, Svetlana, Wulff, Tanja, Kronthaler, Kerstin, Schrepfer, Sabine, Parnitzke, Ulrike, Bretz, Anne Catherine, Baumgartner, Roland, Ferrucci, Veronica, Pennino, Francesco Paolo, Dassi, Luisa, Asadzadeh, Fatemeh, Siciliano, Roberto, Carotenuto, Marianeve, Spano, Daniela, Chiarolla, Cristina Maria, Greco, Adelaide, Cantile, Monica, Di Bonito, Maurizio, Botti, Gerardo, Jonathan, Vandenbussche, Kris, Gevaert, Zollo, Massimo, Amaral, Teresa, Tampouri, Ioanna, Keim, Ulrike, Eigentler, Thomas, Garbe, Claus, Forschner, Andrea, Cesano, Alessandra, Warren, Sarah, Moogk, Duane, Li, Kaitao, Yuan, Zhou, Zhong, Shi, Yu, Zhiya, Liadi, Ivan, Rittase, William, Fang, Victoria, Dougherty, Janna, Perez-Garcia, Arianne, Osman, Iman, Varadarajan, Navin, Restifo, Nicholas P., Frey, Alan, Zhu, Cheng, Krogsgaard, Michelle, Vanpouille-Box, Claire, Formenti, Silvia C., Demaria, Sandra, Nigro, Cristiana Lo, Renziehausen, Alexander, Tzakos, Andreas G., Wang, Hexiao, Rao, Bhavya, Matin, Rubeta, Harwood, Catherine, Vivenza, Daniela, Tonissi, Federica, Occelli, Marcella, Weir, Lynda, Li, Su, Sim, Van Ren, O’Neill, Kevin, Evans, Alan, Thompson, Alastair, Szlosarek, Peter, Fleming, Colin, Proby, Charlotte, Syed, Nelofer, Merlano, Marco, Crook, Tim, Ferguson, Robert, Simpson, Danny, Martinez, Carlos, Vogelsang, Matjaz, Kazlow, Esther, Wilson, Melissa, Pavlick, Anna, Weber, Jeffrey, Sullivan, Ryan, Flaherty, Keith, Ribas, Antoni, Kirchhoff, Tomas, D’Avino, Antonio, Guida, Licia, Cosacco, Augusto, D’Aniello, Roberta, Maiolino, Piera, Tramontano, Teresa, Sarno, Maria R., Palazzo, Ida, Di Napoli, Angela, Acunzo, Gianclaudio, De Fina, Mariarosanna, Silvestri, Antonia, Specchia, Monica, Musacchio, Michela, Giglio, Gianfranco, Carrozza, Francesco, Di Lullo, Liberato, De Maddi, Gian Marco, Venturelli, Adele, Gambale, Elisabetta, Gatta, Alessia, Brocco, Davide, Carella, Consiglia, De Tursi, Michele, Gajewski, Thomas F., Cristiani, Costanza M., Tallerico, Rossana, Ventura, Valeria, Capone, Mariaelena, Madonna, Gabriele, Mallardo, Domenico, Selinger, Eliska, Garofalo, Cinzia, Staaf, Elina, Simeone, Ester, Grimaldi, Antonio M., del Zotto, Genny, Gulletta, Elio, Ciliberto, Gennaro, Moretta, Alessandro, Ascierto, Paolo A., Carbone, Ennio, Costantini, Susan, Sorice, Angela, Capone, Francesca, Ciliberto, Gennaro, Budillon, Alfredo, Cauchi, Carolina, Sciancalepore, Grazia, Nigro, Cristiana Lo, Rovera, Michela, Varamo, Chiara, Seia, Zelda, Palazzini, Stefania, Errico, Fabiana, Basso, Davide, Quaranta, Laura, Forte, Giuseppe, Lavagna, Fulvio, Violante, Silvia, Bosio, Paolo, Lattanzio, Laura, Merlano, Marco C, Gowen, Mike, Tchack, Jeremy, Zhou, Hua, Giles, Keith, Paschke, Scott, Moran, Una, Fenyo, David, Tsirigos, Aris, Pacold, Michael, Morello, Silvana, Sorrentino, Claudia, Giannarelli, Diana, Pinto, Aldo, Fratangelo, Federica, Falcone, Rosaria, Vanella, Vito, Schadendorf, Dirk, Lewis, Karl, Maio, Michele, Demidov, Lev, Mandalà, Mario, Bondarenko, Igor, Herbert, Christopher, Mackiewicz, Andrzej, Rutkowski, Piotr, Guminski, Alexander, Goodman, Grant, Simmons, Brian, Ye, Chenglin, Hooper, Gregory, Wongchenko, Matthew J., Yan, Yibing, Hermann, Frank, Ammendola, Astrid, Hamm, Svetlana, Bartz, René, Alessandra, Bulotta, Letizia, Colombo, Aurora, Mirabile, Chiara, Lazzari, Raffaele, Mercuri Santo, Danilo, Parolini, Nathalie, Rizzo, Stefano, Martella, Giulio, Modorati, Pina, Brianti, Enza, Cestone, Federica, Bellinzona, Elisabetta, Miserocchi, Luca, Gianni, Vanesa, Gregorc, Agarwala, Sanjiv, Mark Smithers, B., Haushild, Axel, Watcher, Eric, Fattore, Luigi, Ruggiero, Ciro Francesco, Liguoro, Domenico, Cerri, Andrea, Pisanu, Maria Elena, Mancini, RitaEnlace del recurso
Publicado 2018
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30828por Wang, Zezhao, Ma, Haoran, Xu, Lei, Zhu, Bo, Liu, Ying, Bordbar, Farhad, Chen, Yan, Zhang, Lupei, Gao, Xue, Gao, Huijiang, Zhang, Shengli, Xu, Lingyang, Li, Junya“…These genes were reported to be associated with fatty acids, such as Bos taurus nitric oxide synthase 1 adaptor protein (NOS1AP), Bos taurus hydroxysteroid 17-beta dehydrogenase 7 (HSD17B7), Bos taurus WD repeat domain 7 (WDR7), Bos taurus ELOVL fatty acid elongase 2 (ELOVL2), Bos taurus calpain 1 (CAPN1), Bos taurus parkin RBR E3 ubiquitin protein ligase (PRKN, also known as PARK2), Bos taurus mitogen-activated protein kinase kinase 6 (MAP2K6), meat quality, including Bos taurus ADAM metallopeptidase domain 12 (ADAM12), Bos taurus 5′-aminolevulinate synthase 1 (ALAS1), Bos taurus small integral membrane protein 13 (SMIM13) and Bos taurus potassium two pore domain channel subfamily K member 2 (KCNK2), growth, and developmental traits, such as Bos taurus insulin like growth factor 2 receptor (IGF2R), Bos taurus RAR related orphan receptor A (RORA), Bos taurus fibroblast growth factor 14 (FGF14), Bos taurus paired box 6 (PAX6) and Bos taurus LIM homeobox 6 (LHX6). …”
Publicado 2019
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30829por Sannino, Giuseppina, Marchetto, Aruna, Ranft, Andreas, Jabar, Susanne, Zacherl, Constanze, Alba-Rubio, Rebeca, Stein, Stefanie, Wehweck, Fabienne S., Kiran, Merve M., Hölting, Tilman L.B., Musa, Julian, Romero-Pérez, Laura, Cidre-Aranaz, Florencia, Knott, Maximilian M.L., Li, Jing, Jürgens, Heribert, Sastre, Ana, Alonso, Javier, Da Silveira, Willian, Hardiman, Gary, Gerke, Julia S., Orth, Martin F., Hartmann, Wolfgang, Kirchner, Thomas, Ohmura, Shunya, Dirksen, Uta, Grünewald, Thomas G.P.“…Since cancer stemness has been associated with tumour relapse and poor patient outcomes, we investigated in the current study the prognostic potential SOX2 (sex determining region Y box 2) – a major transcription factor involved in development and stemness – which was previously described to contribute to the undifferentiated phenotype of EwS. …”
Publicado 2019
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30830por Sloan, Stephen, Wipplinger, Christoph, Kirnaz, Sirtac, Navarro-Ramirez, Rodrigo, Schivinato, Antonella, Härtl, Roger, Bonassar, Lawrence“…IVDs were randomized into 5 treatment groups: 1) intact discs, 2) discs injured via a 3 cm x 1 cm box annulotomy and partial nucleotomy, 3) injury followed by a high density collagen (HDC) AF patch, 4) injury followed by injection of a modified hyaluronic acid (HA) into the NP, and 5) injury followed by both the HDC AF patch and HA NP injection. …”
Publicado 2019
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30831por Staffaroni, Adam M., Goh, Sheng-Yang M., Cobigo, Yann, Ong, Elise, Lee, Suzee E., Casaletto, Kaitlin B., Wolf, Amy, Forsberg, Leah K., Ghoshal, Nupur, Graff-Radford, Neill R., Grossman, Murray, Heuer, Hilary W., Hsiung, Ging-Yuek R., Kantarci, Kejal, Knopman, David S., Kremers, Walter K., Mackenzie, Ian R., Miller, Bruce L., Pedraza, Otto, Rascovsky, Katya, Tartaglia, M. Carmela, Wszolek, Zbigniew K., Kramer, Joel H., Kornak, John, Boeve, Bradley F., Boxer, Adam L., Rosen, Howard J.“…The study also analyzed rates of clinical decline in each of these groups, as measured by the CDR + NACC FTLD box score. RESULTS: The sample included 100 participants with f-FTLD with a known pathogenic variant (mean [SD] age, 50.48 [13.78] years; 53 [53%] female) and 60 family members of known pathogenic variant carriers who did not carry the pathogenic variant (mean [SD] age, 47.51 [12.43] years; 36 [60%] female). …”
Publicado 2020
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30832por Ljubenkov, Peter A., Edwards, Lauren, Iaccarino, Leonardo, La Joie, Renaud, Rojas, Julio C., Koestler, Mary, Harris, Baruch, Boeve, Bradley F., Borroni, Barbara, van Swieten, John C., Grossman, Murray, Pasquier, Florence, Frisoni, Giovanni B., Mummery, Catherine J., Vandenberghe, Rik, Le Ber, Isabelle, Hannequin, Didier, McGinnis, Scott M., Auriacombe, Sophie, Onofrj, Marco, Goodman, Ira J., Riordan, Henry J., Wisniewski, Gary, Hesterman, Jacob, Marek, Ken, Haynes, Beth Ann, Patzke, Holger, Koenig, Gerhard, Hilt, Dana, Moebius, Hans, Boxer, Adam L.“…In a cross-sectional analysis of 26 individuals, bifrontal cortical FDG hypometabolism was associated with worse Clinical Dementia Rating (CDR) plus National Alzheimer’s Coordinating Center frontotemporal lobar degeneration sum of boxes score (b = −3.6 × 10(−2) standardized uptake value ratio [SUVR] units/CDR units; 95% CI, −4.9 × 10(−2) to −2.2 × 10(−2); P < .001), high cerebrospinal fluid NfL (b = −9.2 × 10(−5) SUVR units/pg NfL/mL; 95% CI, −1.3 × 10(−4) to −5.6 × 10(−5); P < .001), and high CSF t-tau (−7.2 × 10(−4) SUVR units/pg t-tau/mL; 95% CI, −1.4 × 10(−3) to −9.5 × 10(−5); P = .03). …”
Publicado 2021
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30833por Shirazi-Tehrani, Elham, Chamasemani, Alireza, Firouzabadi, Negar, Mousaei, Marzieh“…Abbreviations : CVD: cardiovascular disease; BP: blood pressure; HTN: hypertension, lncRNAs: long noncoding RNAs; p38-MAPK: p38-mitogenactivated protein kinase; OPCs: oligomeric procyanidins; GTP: guanosine triphosphate; ROS: reactive oxygen species; cGMP: cyclic guanosine monophosphate; SGC: soluble guanylate cyclase; PI3K: phosphatidylinositol 3-kinase; cGMP: Cyclic GMP; eNOS: endothelial NO synthase; ERK ½: extracellular signal-regulated kinase ½; L-Arg: L-Arginine; MAPK: mitogen-activated protein kinases; NO: Nitric oxide; P: Phosphorus; PDK1: Phosphoinositide-dependent kinase 1; PI3-K: Phosphatidylinositol 3-kinase; PIP2: Phosphatidylinositol diphosphate; ncRNAs: non-protein-coding RNA; miRNAs: microRNAs; OPCs: oligomeric procyanidins; RES: resveratrol; GE: grape extract; T2DM: type 2 diabetes mellitus; IL: interleukin; TNF-α: tumour necrosis factor-alpha; NF-κB: nuclear factor NF-kappa-B; ALP: alkaline phosphatase; PARP1: poly [ADP-ribose] polymerase 1; HIF1a: Hypoxia-inducible-factor 1A; NFATc2: nuclear factor of activated T cells 2; PAD: peripheral artery disease; SHR: spontaneously hypertensive rat; RAAS: renin-angiotensin-aldosterone system; AT(1)R: angiotensin type-1 receptor; Nox: NADPH oxidase; HO-1: haem oxygenase-1; JAK/STAT: Janus kinase/signal transducers/activators of the transcription; PNS: panax notoginseng saponin; snoRNA: small nucleolar RNA; hnRNA: heterogeneous nuclear RNA; VSMCs: vascular smooth muscle cells; irf7: interferon regulatory factor 7; limo2: LIM only domain 2; GWAS: genome-wide association study; GAS5: Growth arrest-specific 5; Asb3, Ankyrin repeat and SPCS box containing 3; Chac2: cation transport regulator homolog 2; Pex11b: peroxisomal membrane 11B; Sp5: Sp5 transcription factor; EGCG: epigallocatechin gallate; ApoE: Apo lipoprotein E; ERK-MAP kinase: extracellular signal-regulated kinases-mitogen-activated protein kinase; PAH: pulmonary artery hypertension; PAP: pulmonary arterial pressure; HIF1a: hypoxia-inducible-factor 1A; NFATc2: nuclear factor of activated T cells 2; HMEC-1: Human microvascular endothelial cells; stat2: signal transducers and activators of transcription 2; JNK: c-Jun N-terminal kinase; iNOS: inducible NO synthase. …”
Publicado 2022
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30834por Peiter, Gabrielle Caroline, de Souza, Cristiano de Bem Torquato, de Oliveira, Lucca Miketen, Pagliarin, Luis Gustavo, dos Anjos, Valentina Nunes Fontoura, da Silva, Filipe Antônio França, de Melo, Fabrício Freire, Teixeira, Kádima Nayara“…AutoDock Tools (ADT) software was used to calculate and delimit the Grid box used in the molecular docking of each structure selected in the PDB. …”
Publicado 2022
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30835por Ebbing, Marco Antônio, Yacoubi, Nadia, Naranjo, Victor, Sitzmann, Werner, Gierus, Martin“…A total of 1008 one-day-old male Ross 308 broiler chickens were placed in a 6 × 2 (6 energy levels and 2 conditionings) factorial trial with six boxes as replications, with three in each broiler performance trial period. …”
Publicado 2022
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30836por Chiew, B A, Lyden, K A, Schick, A, Ohland, C, McCoy, K, Kaur, S, Yousuf, M, Taylor, L, Raman, M, Vallance, J K“…PLEASE ACKNOWLEDGE ALL FUNDING AGENCIES BY CHECKING THE APPLICABLE BOXES BELOW: Other PLEASE INDICATE YOUR SOURCE OF FUNDING; Alberta's Collaboration of Excellence for Nutrition in Digestive Diseases (ASCEND) DISCLOSURE OF INTEREST: B. …”
Publicado 2023
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30837“…PLEASE ACKNOWLEDGE ALL FUNDING AGENCIES BY CHECKING THE APPLICABLE BOXES BELOW: CIHR DISCLOSURE OF INTEREST: S. Coward: None Declared, S. …”
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30838“…PLEASE ACKNOWLEDGE ALL FUNDING AGENCIES BY CHECKING THE APPLICABLE BOXES BELOW: None DISCLOSURE OF INTEREST: None Declared…”
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30839por Hassaniazad, Mehdi, Inchehsablagh, Behnaz Rahnama, Kamali, Hossein, Tousi, Abdolali, Eftekhar, Ebrahim, Jaafari, Mahmoud Reza, Fathalipour, Mohammad, Nikoofal-Sahlabadi, Sara, Gouklani, Hamed, Alizade, Hesam, Nikpoor, Amin Reza“…RANDOMISATION: Randomized trials will be performed on 40 COVID-19 patients which will be randomized using encoded sealed boxes with computer generated random digits with 1:1 allocation ratio. …”
Publicado 2020
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30840por Shen, Yanyan, Xue, Jinqi, Yu, Jiahui, Jiang, Yi, Bu, Jiawen, Zhu, Tong, Gu, Xi, Zhu, Xudong“…The STRING database, DAVID database, and Sanger-box tools were utilized to perform GO functional, KEGG pathway enrichment, and GSEA analysis. …”
Publicado 2022
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